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Intra-tumour heterogeneity: a looking glass for cancer?
Marusyk A, Almendro V, Polyak K. Marusyk A, et al. Among authors: almendro v. Nat Rev Cancer. 2012 Apr 19;12(5):323-34. doi: 10.1038/nrc3261. Nat Rev Cancer. 2012. PMID: 22513401 Review.
In situ single-cell analysis identifies heterogeneity for PIK3CA mutation and HER2 amplification in HER2-positive breast cancer.
Janiszewska M, Liu L, Almendro V, Kuang Y, Paweletz C, Sakr RA, Weigelt B, Hanker AB, Chandarlapaty S, King TA, Reis-Filho JS, Arteaga CL, Park SY, Michor F, Polyak K. Janiszewska M, et al. Among authors: almendro v. Nat Genet. 2015 Oct;47(10):1212-9. doi: 10.1038/ng.3391. Epub 2015 Aug 24. Nat Genet. 2015. PMID: 26301495 Free PMC article.
Evolutionary pathways in BRCA1-associated breast tumors.
Martins FC, De S, Almendro V, Gönen M, Park SY, Blum JL, Herlihy W, Ethington G, Schnitt SJ, Tung N, Garber JE, Fetten K, Michor F, Polyak K. Martins FC, et al. Among authors: almendro v. Cancer Discov. 2012 Jun;2(6):503-11. doi: 10.1158/2159-8290.CD-11-0325. Epub 2012 Apr 10. Cancer Discov. 2012. PMID: 22628410 Free PMC article.
Cellular heterogeneity and molecular evolution in cancer.
Almendro V, Marusyk A, Polyak K. Almendro V, et al. Annu Rev Pathol. 2013 Jan 24;8:277-302. doi: 10.1146/annurev-pathol-020712-163923. Epub 2012 Oct 22. Annu Rev Pathol. 2013. PMID: 23092187 Review.
Intratumor heterogeneity defines treatment-resistant HER2+ breast tumors.
Rye IH, Trinh A, Saetersdal AB, Nebdal D, Lingjaerde OC, Almendro V, Polyak K, Børresen-Dale AL, Helland Å, Markowetz F, Russnes HG. Rye IH, et al. Among authors: almendro v. Mol Oncol. 2018 Nov;12(11):1838-1855. doi: 10.1002/1878-0261.12375. Epub 2018 Sep 21. Mol Oncol. 2018. PMID: 30133130 Free PMC article.
The Proliferative Activity of Mammary Epithelial Cells in Normal Tissue Predicts Breast Cancer Risk in Premenopausal Women.
Huh SJ, Oh H, Peterson MA, Almendro V, Hu R, Bowden M, Lis RL, Cotter MB, Loda M, Barry WT, Polyak K, Tamimi RM. Huh SJ, et al. Among authors: almendro v. Cancer Res. 2016 Apr 1;76(7):1926-34. doi: 10.1158/0008-5472.CAN-15-1927. Epub 2016 Mar 3. Cancer Res. 2016. PMID: 26941287 Free PMC article.
Differential expression of neurogenes among breast cancer subtypes identifies high risk patients.
Fernández-Nogueira P, Bragado P, Almendro V, Ametller E, Rios J, Choudhury S, Mancino M, Gascón P. Fernández-Nogueira P, et al. Among authors: almendro v. Oncotarget. 2016 Feb 2;7(5):5313-26. doi: 10.18632/oncotarget.6543. Oncotarget. 2016. PMID: 26673618 Free PMC article.
Non-cell-autonomous driving of tumour growth supports sub-clonal heterogeneity.
Marusyk A, Tabassum DP, Altrock PM, Almendro V, Michor F, Polyak K. Marusyk A, et al. Among authors: almendro v. Nature. 2014 Oct 2;514(7520):54-8. doi: 10.1038/nature13556. Epub 2014 Jul 30. Nature. 2014. PMID: 25079331 Free PMC article.
JARID1B is a luminal lineage-driving oncogene in breast cancer.
Yamamoto S, Wu Z, Russnes HG, Takagi S, Peluffo G, Vaske C, Zhao X, Moen Vollan HK, Maruyama R, Ekram MB, Sun H, Kim JH, Carver K, Zucca M, Feng J, Almendro V, Bessarabova M, Rueda OM, Nikolsky Y, Caldas C, Liu XS, Polyak K. Yamamoto S, et al. Among authors: almendro v. Cancer Cell. 2014 Jun 16;25(6):762-77. doi: 10.1016/j.ccr.2014.04.024. Cancer Cell. 2014. PMID: 24937458 Free PMC article.
Inference of tumor evolution during chemotherapy by computational modeling and in situ analysis of genetic and phenotypic cellular diversity.
Almendro V, Cheng YK, Randles A, Itzkovitz S, Marusyk A, Ametller E, Gonzalez-Farre X, Muñoz M, Russnes HG, Helland A, Rye IH, Borresen-Dale AL, Maruyama R, van Oudenaarden A, Dowsett M, Jones RL, Reis-Filho J, Gascon P, Gönen M, Michor F, Polyak K. Almendro V, et al. Cell Rep. 2014 Feb 13;6(3):514-27. doi: 10.1016/j.celrep.2013.12.041. Epub 2014 Jan 23. Cell Rep. 2014. PMID: 24462293 Free PMC article.
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