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Unveiling the role of network and systems biology in drug discovery.
Pujol A, Mosca R, Farrés J, Aloy P. Pujol A, et al. Among authors: aloy p. Trends Pharmacol Sci. 2010 Mar;31(3):115-23. doi: 10.1016/j.tips.2009.11.006. Epub 2010 Feb 1. Trends Pharmacol Sci. 2010. PMID: 20117850 Review.
Structural systems biology: modelling protein interactions.
Aloy P, Russell RB. Aloy P, et al. Nat Rev Mol Cell Biol. 2006 Mar;7(3):188-97. doi: 10.1038/nrm1859. Nat Rev Mol Cell Biol. 2006. PMID: 16496021 Review.
Towards a molecular characterisation of pathological pathways.
Pache RA, Zanzoni A, Naval J, Mas JM, Aloy P. Pache RA, et al. Among authors: aloy p. FEBS Lett. 2008 Apr 9;582(8):1259-65. doi: 10.1016/j.febslet.2008.02.014. Epub 2008 Feb 20. FEBS Lett. 2008. PMID: 18282477 Review.
Incorporating high-throughput proteomics experiments into structural biology pipelines: identification of the low-hanging fruits.
Pache RA, Aloy P. Pache RA, et al. Among authors: aloy p. Proteomics. 2008 May;8(10):1959-64. doi: 10.1002/pmic.200700966. Proteomics. 2008. PMID: 18491310
A network medicine approach to human disease.
Zanzoni A, Soler-López M, Aloy P. Zanzoni A, et al. Among authors: aloy p. FEBS Lett. 2009 Jun 5;583(11):1759-65. doi: 10.1016/j.febslet.2009.03.001. Epub 2009 Mar 6. FEBS Lett. 2009. PMID: 19269289 Review.
Exploiting gene deletion fitness effects in yeast to understand the modular architecture of protein complexes under different growth conditions.
Pache RA, Babu MM, Aloy P. Pache RA, et al. Among authors: aloy p. BMC Syst Biol. 2009 Jul 18;3:74. doi: 10.1186/1752-0509-3-74. BMC Syst Biol. 2009. PMID: 19615085 Free PMC article.
Dynamic interactions of proteins in complex networks: a more structured view.
Stein A, Pache RA, Bernadó P, Pons M, Aloy P. Stein A, et al. Among authors: aloy p. FEBS J. 2009 Oct;276(19):5390-405. doi: 10.1111/j.1742-4658.2009.07251.x. Epub 2009 Aug 27. FEBS J. 2009. PMID: 19712106 Review.
Pushing structural information into the yeast interactome by high-throughput protein docking experiments.
Mosca R, Pons C, Fernández-Recio J, Aloy P. Mosca R, et al. Among authors: aloy p. PLoS Comput Biol. 2009 Aug;5(8):e1000490. doi: 10.1371/journal.pcbi.1000490. Epub 2009 Aug 28. PLoS Comput Biol. 2009. PMID: 19714207 Free PMC article.
Predicting protein-protein interaction specificity through the integration of three-dimensional structural information and the evolutionary record of protein domains.
Panjkovich A, Aloy P. Panjkovich A, et al. Among authors: aloy p. Mol Biosyst. 2010 Apr;6(4):741-9. doi: 10.1039/b918395g. Epub 2010 Feb 23. Mol Biosyst. 2010. PMID: 20237652
Novel peptide-mediated interactions derived from high-resolution 3-dimensional structures.
Stein A, Aloy P. Stein A, et al. Among authors: aloy p. PLoS Comput Biol. 2010 May 20;6(5):e1000789. doi: 10.1371/journal.pcbi.1000789. PLoS Comput Biol. 2010. PMID: 20502673 Free PMC article.
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