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Environmental robustness of the global yeast genetic interaction network.
Costanzo M, Hou J, Messier V, Nelson J, Rahman M, VanderSluis B, Wang W, Pons C, Ross C, Ušaj M, San Luis BJ, Shuteriqi E, Koch EN, Aloy P, Myers CL, Boone C, Andrews B. Costanzo M, et al. Among authors: aloy p. Science. 2021 May 7;372(6542):eabf8424. doi: 10.1126/science.abf8424. Science. 2021. PMID: 33958448 Free PMC article.
Exploring genetic suppression interactions on a global scale.
van Leeuwen J, Pons C, Mellor JC, Yamaguchi TN, Friesen H, Koschwanez J, Ušaj MM, Pechlaner M, Takar M, Ušaj M, VanderSluis B, Andrusiak K, Bansal P, Baryshnikova A, Boone CE, Cao J, Cote A, Gebbia M, Horecka G, Horecka I, Kuzmin E, Legro N, Liang W, van Lieshout N, McNee M, San Luis BJ, Shaeri F, Shuteriqi E, Sun S, Yang L, Youn JY, Yuen M, Costanzo M, Gingras AC, Aloy P, Oostenbrink C, Murray A, Graham TR, Myers CL, Andrews BJ, Roth FP, Boone C. van Leeuwen J, et al. Among authors: aloy p. Science. 2016 Nov 4;354(6312):aag0839. doi: 10.1126/science.aag0839. Science. 2016. PMID: 27811238 Free PMC article.
Systematic analysis of bypass suppression of essential genes.
van Leeuwen J, Pons C, Tan G, Wang JZ, Hou J, Weile J, Gebbia M, Liang W, Shuteriqi E, Li Z, Lopes M, Ušaj M, Dos Santos Lopes A, van Lieshout N, Myers CL, Roth FP, Aloy P, Andrews BJ, Boone C. van Leeuwen J, et al. Among authors: aloy p. Mol Syst Biol. 2020 Sep;16(9):e9828. doi: 10.15252/msb.20209828. Mol Syst Biol. 2020. PMID: 32939983 Free PMC article.
Natural variants suppress mutations in hundreds of essential genes.
Parts L, Batté A, Lopes M, Yuen MW, Laver M, San Luis BJ, Yue JX, Pons C, Eray E, Aloy P, Liti G, van Leeuwen J. Parts L, et al. Among authors: aloy p. Mol Syst Biol. 2021 May;17(5):e10138. doi: 10.15252/msb.202010138. Mol Syst Biol. 2021. PMID: 34042294 Free PMC article.
Analysing the yeast complexome-the Complex Portal rising to the challenge.
Meldal BHM, Pons C, Perfetto L, Del-Toro N, Wong E, Aloy P, Hermjakob H, Orchard S, Porras P. Meldal BHM, et al. Among authors: aloy p. Nucleic Acids Res. 2021 Apr 6;49(6):3156-3167. doi: 10.1093/nar/gkab077. Nucleic Acids Res. 2021. PMID: 33677561 Free PMC article.
Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing.
Yang X, Coulombe-Huntington J, Kang S, Sheynkman GM, Hao T, Richardson A, Sun S, Yang F, Shen YA, Murray RR, Spirohn K, Begg BE, Duran-Frigola M, MacWilliams A, Pevzner SJ, Zhong Q, Wanamaker SA, Tam S, Ghamsari L, Sahni N, Yi S, Rodriguez MD, Balcha D, Tan G, Costanzo M, Andrews B, Boone C, Zhou XJ, Salehi-Ashtiani K, Charloteaux B, Chen AA, Calderwood MA, Aloy P, Roth FP, Hill DE, Iakoucheva LM, Xia Y, Vidal M. Yang X, et al. Among authors: aloy p. Cell. 2016 Feb 11;164(4):805-17. doi: 10.1016/j.cell.2016.01.029. Cell. 2016. PMID: 26871637 Free PMC article.
A PanorOmic view of personal cancer genomes.
Mateo L, Guitart-Pla O, Pons C, Duran-Frigola M, Mosca R, Aloy P. Mateo L, et al. Among authors: aloy p. Nucleic Acids Res. 2017 Jul 3;45(W1):W195-W200. doi: 10.1093/nar/gkx311. Nucleic Acids Res. 2017. PMID: 28453651 Free PMC article.
Structure-based assembly of protein complexes in yeast.
Aloy P, Böttcher B, Ceulemans H, Leutwein C, Mellwig C, Fischer S, Gavin AC, Bork P, Superti-Furga G, Serrano L, Russell RB. Aloy P, et al. Science. 2004 Mar 26;303(5666):2026-9. doi: 10.1126/science.1092645. Science. 2004. PMID: 15044803
139 results