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Page 1
Anti-Glomerular Basement Membrane Nephritis Post-Renal Transplant in Alport Syndrome Patients.
Hong L, Mabillard H, Sayer JA. Hong L, et al. Kidney360. 2026 Jul 2. doi: 10.34067/KID.0000001310. Online ahead of print. Kidney360. 2026. PMID: 42390934 Free article.
Post-transplant anti-GBM nephritis is reported to affect 5% of AS patients. There is also an isolated immunological anti-GBM disease counterpart, where despite the production of anti-GBM antibodies, the AS patient doe …
Post-transplant anti-GBM nephritis is reported to affect 5% of AS patients. There is also an isolated imm …
Retransplantation in Alport post-transplant anti-GBM disease.
Browne G, Brown PA, Tomson CR, Fleming S, Allen A, Herriot R, Pusey CD, Rees AJ, Turner AN. Browne G, et al. Kidney Int. 2004 Feb;65(2):675-81. doi: 10.1111/j.1523-1755.2004.00428.x. Kidney Int. 2004. PMID: 14717941 Free article. Review.
BACKGROUND: Post transplant anti-glomerular basement membrane (GBM) disease affects up to 5% of patients with Alport's syndrome. ...Anti-GBM antibodies in these cases were investigated by standard anti-GBM enzyme-linked immu …
BACKGROUND: Post transplant anti-glomerular basement membrane (GBM) disease affects up to 5% of patients with Alport's …
Quaternary epitopes of alpha345(IV) collagen initiate Alport post-transplant anti-GBM nephritis.
Olaru F, Luo W, Wang XP, Ge L, Hertz JM, Kashtan CE, Sado Y, Segal Y, Hudson BG, Borza DB. Olaru F, et al. J Am Soc Nephrol. 2013 May;24(6):889-95. doi: 10.1681/ASN.2012100978. Epub 2013 Apr 25. J Am Soc Nephrol. 2013. PMID: 23620401 Free PMC article.
Alport post-transplant nephritis (APTN) is an aggressive form of anti-glomerular basement membrane disease that targets the allograft in transplanted patients with X-linked Alport syndrome. ...We found that patients with APTN, but not tho …
Alport post-transplant nephritis (APTN) is an aggressive form of anti-glomerular basement membrane disease that …
The development of anti-glomerular basement membrane nephritis in two children with Alport's syndrome after renal transplantation: characterization of the antibody target.
vd Heuvel LP, Schröder CH, Savage CO, Menzel D, Assmann KJ, Monnens LA, Veerkamp JH. vd Heuvel LP, et al. Pediatr Nephrol. 1989 Oct;3(4):406-13. doi: 10.1007/BF00850217. Pediatr Nephrol. 1989. PMID: 2642109
Two children with Alport's syndrome are described, who developed anti-glomerular basement membrane (GMB) antibody-mediated nephritis after renal transplantation. ...Since abnormalities in the composition of the GBM are present in Alport's syndrome …
Two children with Alport's syndrome are described, who developed anti-glomerular basement membrane (GMB) antibody-mediated …
A COL4A3 gene mutation and post-transplant anti-alpha 3(IV) collagen alloantibodies in Alport syndrome.
Kalluri R, van den Heuvel LP, Smeets HJ, Schroder CH, Lemmink HH, Boutaud A, Neilson EG, Hudson BG. Kalluri R, et al. Kidney Int. 1995 Apr;47(4):1199-204. doi: 10.1038/ki.1995.170. Kidney Int. 1995. PMID: 7783419 Free article.
The autosomal recessive form of Alport syndrome is characterized by mutations and deletions in the COL4A3 and COL4A4 genes. ...The present study characterized the post-transplant alloantibodies from an autosomal recessive Alport patient with …
The autosomal recessive form of Alport syndrome is characterized by mutations and deletions in the COL4A3 and COL4A4 genes. .. …
COL4A5 gene deletion and production of post-transplant anti-alpha 3(IV) collagen alloantibodies in Alport syndrome.
Kalluri R, Weber M, Netzer KO, Sun MJ, Neilson EG, Hudson BG. Kalluri R, et al. Kidney Int. 1994 Mar;45(3):721-6. doi: 10.1038/ki.1994.96. Kidney Int. 1994. PMID: 8196274 Free article.
Mutations in the COL4A5 gene encoding the alpha 5(IV) chain of type IV collagen have been implicated as the primary defect in X-linked Alport syndrome. Several kinds of mutations have been reported so far, spanning point mutations to complete gene deletions. ...In t …
Mutations in the COL4A5 gene encoding the alpha 5(IV) chain of type IV collagen have been implicated as the primary defect in X-linked Al …
The pathogenesis of Alport syndrome involves type IV collagen molecules containing the alpha 3(IV) chain: evidence from anti-GBM nephritis after renal transplantation.
Hudson BG, Kalluri R, Gunwar S, Weber M, Ballester F, Hudson JK, Noelken ME, Sarras M, Richardson WR, Saus J, et al. Hudson BG, et al. Kidney Int. 1992 Jul;42(1):179-87. doi: 10.1038/ki.1992.276. Kidney Int. 1992. PMID: 1635348 Free article.
In the present study, the molecular nature of the defect in Alport glomerular basement membrane (GBM) was explored using anti-GBM alloantibodies (tissue-bound and circulating) produced in three Alport patients subsequent to renal transplantation. ...In …
In the present study, the molecular nature of the defect in Alport glomerular basement membrane (GBM) was explored using anti- …
Identification of post-transplant anti-alpha 5 (IV) collagen alloantibodies in X-linked Alport syndrome.
Dehan P, Van den Heuvel LP, Smeets HJ, Tryggvason K, Foidart JM. Dehan P, et al. Nephrol Dial Transplant. 1996 Oct;11(10):1983-8. doi: 10.1093/oxfordjournals.ndt.a027085. Nephrol Dial Transplant. 1996. PMID: 8918711
X-linked Alport syndrome (AS) is a heritable disorder which is associated with mutations in the type IV collagen alpha 5 (IV) chain gene (COL4A5) located on chromosome X. Following renal transplantation, an average of 6% of male AS patients develop anti-GB …
X-linked Alport syndrome (AS) is a heritable disorder which is associated with mutations in the type IV collagen alpha 5 (IV) …
Renal transplantation in patients with Alport syndrome.
Kashtan CE. Kashtan CE. Pediatr Transplant. 2006 Sep;10(6):651-7. doi: 10.1111/j.1399-3046.2006.00528.x. Pediatr Transplant. 2006. PMID: 16911486 Review.
For pediatric kidney transplant physicians, two aspects of Alport syndrome set the disease apart from other causes of terminal renal failure. First, an understanding of the genetics of Alport syndrome is needed to make appropriate decisions regarding p …
For pediatric kidney transplant physicians, two aspects of Alport syndrome set the disease apart from other causes of terminal …
Induction of anti-GBM nephritis in rats by recombinant alpha 3(IV)NC1 and alpha 4(IV)NC1 of type IV collagen.
Sado Y, Boutaud A, Kagawa M, Naito I, Ninomiya Y, Hudson BG. Sado Y, et al. Kidney Int. 1998 Mar;53(3):664-71. doi: 10.1046/j.1523-1755.1998.00795.x. Kidney Int. 1998. PMID: 9507212 Free article.
The renal lesions induced by alpha 3(IV)NC1 and alpha 4(IV)NC1 domains were characteristic of those in patients with anti-GBM nephritis and Goodpasture syndrome. The experimental nephritis is mediated by anti-basement membrane antibodies that ar …
The renal lesions induced by alpha 3(IV)NC1 and alpha 4(IV)NC1 domains were characteristic of those in patients with anti-GBM …
17 results