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Alstonia scholaris (L.) R. Br. ameliorated diabetic nephropathy through PPAR-delta pathway.
Qin SS, Tian CB, Qian YL, Wu XR, Wen X, Zhao YL, Luo XD. Qin SS, et al. J Ethnopharmacol. 2025 May 28;348:119839. doi: 10.1016/j.jep.2025.119839. Epub 2025 Apr 26. J Ethnopharmacol. 2025. PMID: 40294665
ETHNOPHARMACOLOGICAL RELEVANCE: Alstonia scholaris was utilized as a medicinal herb for the management of diabetes traditionally, with diabetic nephropathy (DN) was one of its major complications. However, the effect of A. scholaris on DN have yet to be explo …
ETHNOPHARMACOLOGICAL RELEVANCE: Alstonia scholaris was utilized as a medicinal herb for the management of diabetes traditional …
Alstonia scholaris (L.) R. Br. and Alstonia macrophylla Wall. ex G. Don: A comparative review on traditional uses, phytochemistry and pharmacology.
Khyade MS, Kasote DM, Vaikos NP. Khyade MS, et al. J Ethnopharmacol. 2014 Apr 11;153(1):1-18. doi: 10.1016/j.jep.2014.01.025. Epub 2014 Jan 28. J Ethnopharmacol. 2014. PMID: 24486598 Review.
ETHNOPHARMACOLOGICAL RELEVANCE: Alstonia scholaris (L.) R. Br. and Alstonia macrophylla Wall. ex G. Don are two vital medicinal plant species (family: Apocynaceae). ...In India, Alstonia macrophylla is used as a substitute for Alstonia schola …
ETHNOPHARMACOLOGICAL RELEVANCE: Alstonia scholaris (L.) R. Br. and Alstonia macrophylla Wall. ex G. Don are two vital m …
New Lupanes from Alstonia scholaris Reducing Uric Acid Level.
Hu BY, Zhao YL, Xu Y, Wang XN, Luo XD. Hu BY, et al. Planta Med. 2023 Oct 19. doi: 10.1055/a-2186-3260. Online ahead of print. Planta Med. 2023. PMID: 37857337
Twelve lupanes including three new compounds named alstoscholarilups A-C (1: -3: ) were isolated from the leaves of Alstonia scholaris. Their structures were elucidated by spectroscopic analysis and ECD calculation. ...
Twelve lupanes including three new compounds named alstoscholarilups A-C (1: -3: ) were isolated from the leaves of Alstonia schol …
Anti-hyperuricemic bioactivity of Alstonia scholaris and its bioactive triterpenoids in vivo and in vitro.
Hu BY, Zhao YL, Ma DY, Xiang ML, Zhao LX, Luo XD. Hu BY, et al. J Ethnopharmacol. 2022 May 23;290:115049. doi: 10.1016/j.jep.2022.115049. Epub 2022 Feb 9. J Ethnopharmacol. 2022. PMID: 35150817
ETHNOPHARMACOLOGY RELEVANCE: One folk use of Alstonia scholaris (L.) R. Br. in "Dai" ethno-medicine system is to treat gouty arthritis, which might be caused by hyperuricemia, but anti-hyperuricemic investigation of A. scholaris were rarely reported. ...CONCL …
ETHNOPHARMACOLOGY RELEVANCE: One folk use of Alstonia scholaris (L.) R. Br. in "Dai" ethno-medicine system is to treat gouty a …
Undescribed indole lactones from Alstonia scholaris protecting hepatic cell damage.
Hu BY, Zhao YL, He YJ, Qin Y, Luo XD. Hu BY, et al. Phytochemistry. 2024 Jan;217:113926. doi: 10.1016/j.phytochem.2023.113926. Epub 2023 Nov 17. Phytochemistry. 2024. PMID: 37981062
Six previously undescribed rigidly monoterpenoid indole alkaloids, alstolactines F-K (1-6), were isolated from Alstonia scholaris. Among them, a pair of cage-like epimers, 1 and 2, featuring a rare 6/5/6/6/7 ring system, represent the first example of C(5) C(20)-oli …
Six previously undescribed rigidly monoterpenoid indole alkaloids, alstolactines F-K (1-6), were isolated from Alstonia scholaris …
Alstonia scholaris Linn R Br in the treatment and prevention of cancer: past, present, and future.
Manjeshwar Shrinath Baliga. Manjeshwar Shrinath Baliga. Integr Cancer Ther. 2010 Sep;9(3):261-9. doi: 10.1177/1534735410376068. Epub 2010 Aug 11. Integr Cancer Ther. 2010. PMID: 20702494 Free article. Review.
Alstonia scholaris, commonly known as devil's tree, is an important medicinal plant in the various folk and traditional systems of medicine in Asia, Australia, and Africa. ...In addition to the cytotoxic effects, A scholaris is also observed to possess radiom …
Alstonia scholaris, commonly known as devil's tree, is an important medicinal plant in the various folk and traditional system …
Monoterpenoid indole alkaloids from Alstonia scholaris and their Toxoplasma gondii inhibitory activity.
Wu PQ, Liu ZD, Ren YH, Zhou JS, Liu QF, Wu Y, Zhang JL, Zhou B, Yue JM. Wu PQ, et al. Phytochemistry. 2024 Apr;220:113993. doi: 10.1016/j.phytochem.2024.113993. Epub 2024 Jan 22. Phytochemistry. 2024. PMID: 38266954
Nine previously unreported various types of monoterpenoid indole alkaloids, together with seven known analogues were isolated from the stem barks of Alstonia scholaris through a silica gel free methodology. The structures of 1-9 were elucidated by spectroscopic data …
Nine previously unreported various types of monoterpenoid indole alkaloids, together with seven known analogues were isolated from the stem …
Preface.
Knölker HJ. Knölker HJ. Alkaloids Chem Biol. 2019;81:ix-x. doi: 10.1016/S1099-4831(19)30008-2. Alkaloids Chem Biol. 2019. PMID: 30685051 No abstract available.
Chromosome-level Alstonia scholaris genome unveils evolutionary insights into biosynthesis of monoterpenoid indole alkaloids.
Chen H, Sahu SK, Wang S, Liu J, Yang J, Cheng L, Chiu TY, Liu H. Chen H, et al. iScience. 2024 Mar 27;27(5):109599. doi: 10.1016/j.isci.2024.109599. eCollection 2024 May 17. iScience. 2024. PMID: 38646178 Free PMC article.
Alstonia scholaris of the Apocynaceae family is a medicinal plant with a rich source of bioactive monoterpenoid indole alkaloids (MIAs), which possess anti-cancer activity like vinca alkaloids. To gain genomic insights into MIA biosynthesis, we assembled a high-qual …
Alstonia scholaris of the Apocynaceae family is a medicinal plant with a rich source of bioactive monoterpenoid indole alkaloi …
Pharmacological investigation of indole alkaloids from Alstonia scholaris against chronic glomerulonephritis.
Guo R, Shang JH, Ye RH, Zhao YL, Luo XD. Guo R, et al. Phytomedicine. 2023 Sep;118:154958. doi: 10.1016/j.phymed.2023.154958. Epub 2023 Jul 8. Phytomedicine. 2023. PMID: 37453192
BACKGROUND: As one of the most commonly used folk medicines in "Dai" ethno-medicine system, Alstonia scholaris (l.) R. Br. has also been used for treat "water related diseases", such as chronic kidney disease. ...PURPOSE: To investigate the effect and potential mech …
BACKGROUND: As one of the most commonly used folk medicines in "Dai" ethno-medicine system, Alstonia scholaris (l.) R. Br. has …
420 results