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Alstonia scholaris (L.) R. Br. and Alstonia macrophylla Wall. ex G. Don: A comparative review on traditional uses, phytochemistry and pharmacology.
Khyade MS, Kasote DM, Vaikos NP. Khyade MS, et al. J Ethnopharmacol. 2014 Apr 11;153(1):1-18. doi: 10.1016/j.jep.2014.01.025. Epub 2014 Jan 28. J Ethnopharmacol. 2014. PMID: 24486598 Review.
ETHNOPHARMACOLOGICAL RELEVANCE: Alstonia scholaris (L.) R. Br. and Alstonia macrophylla Wall. ex G. ...In India, Alstonia macrophylla is used as a substitute for Alstonia scholaris in various herbal pharmaceutical preparations. ...
ETHNOPHARMACOLOGICAL RELEVANCE: Alstonia scholaris (L.) R. Br. and Alstonia macrophylla Wall. ex G. ...In India, Als
Four new corynanthe-type alkaloids from the roots of Alstonia scholaris.
Zhang J, Li H, Li Y, Li ZW, Sang CC, Gao MH, Zhang DM, Zhang XQ, Ye WC. Zhang J, et al. Chin J Nat Med. 2019 Dec;17(12):918-923. doi: 10.1016/S1875-5364(19)30113-X. Chin J Nat Med. 2019. PMID: 31882046
Four new corynanthe-type alkaloids, meloslines C-F (1-4), together with four known ones (5-8) were isolated from the roots of Alstonia scholaris. Their structures including absolute configurations were elucidated by extensive spectroscopic analysis and electronic ci …
Four new corynanthe-type alkaloids, meloslines C-F (1-4), together with four known ones (5-8) were isolated from the roots of Alstonia
Complete plastome of the medicinally important plant, Alstonia scholaris (Apocynaceae).
Jin L, Yang J, Liu C, He M. Jin L, et al. Mitochondrial DNA B Resour. 2019 Sep 6;4(2):2896-2897. doi: 10.1080/23802359.2019.1660277. Mitochondrial DNA B Resour. 2019. PMID: 33365780 Free PMC article.
Alstonia scholaris is an evergreen tropical tree with significant medicinal values. ...It possesses 116 unique genes (82 protein-coding genes, 30 tRNAs, and 4 rRNAs). Phylogenetic analysis suggests that A. scholaris is sister to the clade including remaining
Alstonia scholaris is an evergreen tropical tree with significant medicinal values. ...It possesses 116 unique genes (82 prote
Alstonia scholaris Linn R Br in the treatment and prevention of cancer: past, present, and future.
Manjeshwar Shrinath Baliga. Manjeshwar Shrinath Baliga. Integr Cancer Ther. 2010 Sep;9(3):261-9. doi: 10.1177/1534735410376068. Epub 2010 Aug 11. Integr Cancer Ther. 2010. PMID: 20702494 Free article. Review.
Alstonia scholaris, commonly known as devil's tree, is an important medicinal plant in the various folk and traditional systems of medicine in Asia, Australia, and Africa. ...Additionally, the phytochemicals like echitamine, alstonine, pleiocarpamine, O-methylmacral
Alstonia scholaris, commonly known as devil's tree, is an important medicinal plant in the various folk and traditional system
Total alkaloids from Alstonia scholaris inhibit influenza a virus replication and lung immunopathology by regulating the innate immune response.
Zhou HX, Li RF, Wang YF, Shen LH, Cai LH, Weng YC, Zhang HR, Chen XX, Wu X, Chen RF, Jiang HM, Wang C, Yang M, Lu J, Luo XD, Jiang Z, Yang ZF. Zhou HX, et al. Phytomedicine. 2020 Oct;77:153272. doi: 10.1016/j.phymed.2020.153272. Epub 2020 Jun 29. Phytomedicine. 2020. PMID: 32702592
BACKGROUND: Alstonia scholaris is a folk medicine used to treat cough, asthma and chronic obstructive pulmonary disease in China. Total alkaloids (TA) from A. scholaris exhibit anti-inflammatory properties in acute respiratory disease, which suggests their po …
BACKGROUND: Alstonia scholaris is a folk medicine used to treat cough, asthma and chronic obstructive pulmonary disease in Chi …
New Anti-inflammatory Triterpene Esters and Glycosides from Alstonia scholaris.
Sultana N, Qazi MS, Kamal M. Sultana N, et al. Antiinflamm Antiallergy Agents Med Chem. 2020;19(4):370-386. doi: 10.2174/1871523018666190724122406. Antiinflamm Antiallergy Agents Med Chem. 2020. PMID: 31339078
BACKGROUND: Phytochemical studies on the ethanolic extract of aerial parts of Alstonia scholaris lead to the isolation of two new triterpenoid of the lanostanetype, lanosta 5ene,24-ethyl-3-O-beta-D-glucopyranoside (1), lanosta,5ene,24-ethyl-3-O-beta-D-glucopyranosid …
BACKGROUND: Phytochemical studies on the ethanolic extract of aerial parts of Alstonia scholaris lead to the isolation of two …
Ameliorative potential of Alstonia scholaris (Linn.) R. Br. against chronic constriction injury-induced neuropathic pain in rats.
Singh H, Arora R, Arora S, Singh B. Singh H, et al. BMC Complement Altern Med. 2017 Jan 19;17(1):63. doi: 10.1186/s12906-017-1577-7. BMC Complement Altern Med. 2017. PMID: 28103857 Free PMC article.
BACKGROUND: Alstonia scholaris commonly known as 'Saptaparni' is an Indian traditional medicinal plant used in Ayurveda. ...AIM: The present study was designed to investigate the potential of A. scholaris R. Br. in chronic constriction injury of sciatic nerve …
BACKGROUND: Alstonia scholaris commonly known as 'Saptaparni' is an Indian traditional medicinal plant used in Ayurveda. ...AI …
Pharmacokinetics and safety evaluation in healthy Chinese volunteers of alkaloids from leaf of Alstonia scholaris: A multiple doses phase I clinical trial.
Li R, Zi MJ, Gou ZP, Zhao YL, Zhang WT, Lu F, Cao WY, Zhao YP, Li QN, Zhao Y, Wang SG, Gao HY, Sun MY, Luo XD, Xiong ZL, Gao R. Li R, et al. Phytomedicine. 2019 Aug;61:152828. doi: 10.1016/j.phymed.2019.152828. Epub 2019 Jan 10. Phytomedicine. 2019. PMID: 31055046 Clinical Trial.
BACKGROUND: Alstonia scholaris (Apocynaceae) was reported to be a rich source of indole alkaloids, which exhibited remarkably bioactivities. The leaf of A. scholaris has been used in 'dai' ethno-medicine for treatment of respiratory diseases, and the defined …
BACKGROUND: Alstonia scholaris (Apocynaceae) was reported to be a rich source of indole alkaloids, which exhibited remarkably …
Alstonlarsines A-D, Four Rearranged Indole Alkaloids from Alstonia scholaris.
Zhu XX, Fan YY, Xu L, Liu QF, Wu JP, Li JY, Li J, Gao K, Yue JM. Zhu XX, et al. Org Lett. 2019 Mar 1;21(5):1471-1474. doi: 10.1021/acs.orglett.9b00230. Epub 2019 Feb 13. Org Lett. 2019. PMID: 30758208
Four indole alkaloids, alstonlarsines A-D (1-4), were isolated from Alstonia scholaris and structurally characterized. Compound 1 possesses a new carbon skeleton with a cage-shaped 9-azatricyclo[4.3.1.0(3,8)]decane motif, and compounds 2-4 feature a rare carbon skel …
Four indole alkaloids, alstonlarsines A-D (1-4), were isolated from Alstonia scholaris and structurally characterized. Compoun …
Ameliorating effect of Alstonia scholaris L. bark extract on histopathological changes following viper envenomation in animal models.
Ghosh R, Mana K, Sarkhel S. Ghosh R, et al. Toxicol Rep. 2018 Oct 4;5:988-993. doi: 10.1016/j.toxrep.2018.10.004. eCollection 2018. Toxicol Rep. 2018. PMID: 30319940 Free PMC article.
The present study investigates the ameliorating effect of the aqueous bark extract of Alstonia scholaris bark on viper venom induced histopathological and biochemical changes in liver and kidney of swiss albino mice models. ...CONCLUSION: The present paper thus high …
The present study investigates the ameliorating effect of the aqueous bark extract of Alstonia scholaris bark on viper venom i …
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