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Cellular imaging using matrix-enhanced and metal-assisted SIMS.
Altelaar AF, Piersma SR. Altelaar AF, et al. Methods Mol Biol. 2010;656:197-208. doi: 10.1007/978-1-60761-746-4_11. Methods Mol Biol. 2010. PMID: 20680592
Imaging mass spectrometry at cellular length scales.
Altelaar AF, Luxembourg SL, McDonnell LA, Piersma SR, Heeren RM. Altelaar AF, et al. Nat Protoc. 2007;2(5):1185-96. doi: 10.1038/nprot.2007.117. Nat Protoc. 2007. PMID: 17546014
Automated, feature-based image alignment for high-resolution imaging mass spectrometry of large biological samples.
Broersen A, van Liere R, Altelaar AF, Heeren RM, McDonnell LA. Broersen A, et al. J Am Soc Mass Spectrom. 2008 Jun;19(6):823-32. doi: 10.1016/j.jasms.2008.02.015. Epub 2008 Mar 18. J Am Soc Mass Spectrom. 2008. PMID: 18403214
Strong cation exchange-based fractionation of Lys-N-generated peptides facilitates the targeted analysis of post-translational modifications.
Taouatas N, Altelaar AF, Drugan MM, Helbig AO, Mohammed S, Heck AJ. Taouatas N, et al. Mol Cell Proteomics. 2009 Jan;8(1):190-200. doi: 10.1074/mcp.M800285-MCP200. Epub 2008 Sep 29. Mol Cell Proteomics. 2009. PMID: 18824475
Straightforward and de novo peptide sequencing by MALDI-MS/MS using a Lys-N metalloendopeptidase.
Boersema PJ, Taouatas N, Altelaar AF, Gouw JW, Ross PL, Pappin DJ, Heck AJ, Mohammed S. Boersema PJ, et al. Mol Cell Proteomics. 2009 Apr;8(4):650-60. doi: 10.1074/mcp.M800249-MCP200. Epub 2008 Nov 29. Mol Cell Proteomics. 2009. PMID: 19043101 Free PMC article.
Improved identification of endogenous peptides from murine nervous tissue by multiplexed peptide extraction methods and multiplexed mass spectrometric analysis.
Altelaar AF, Mohammed S, Brans MA, Adan RA, Heck AJ. Altelaar AF, et al. J Proteome Res. 2009 Feb;8(2):870-6. doi: 10.1021/pr800449n. J Proteome Res. 2009. PMID: 19152261
Tissue analysis with high-resolution imaging mass spectrometry.
Altelaar AF, Heeren RM. Altelaar AF, et al. Methods Mol Biol. 2009;492:295-308. doi: 10.1007/978-1-59745-493-3_18. Methods Mol Biol. 2009. PMID: 19241041
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