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SARS-CoV-2 infection protects against rechallenge in rhesus macaques.
Chandrashekar A, Liu J, Martinot AJ, McMahan K, Mercado NB, Peter L, Tostanoski LH, Yu J, Maliga Z, Nekorchuk M, Busman-Sahay K, Terry M, Wrijil LM, Ducat S, Martinez DR, Atyeo C, Fischinger S, Burke JS, Slein MD, Pessaint L, Van Ry A, Greenhouse J, Taylor T, Blade K, Cook A, Finneyfrock B, Brown R, Teow E, Velasco J, Zahn R, Wegmann F, Abbink P, Bondzie EA, Dagotto G, Gebre MS, He X, Jacob-Dolan C, Kordana N, Li Z, Lifton MA, Mahrokhian SH, Maxfield LF, Nityanandam R, Nkolola JP, Schmidt AG, Miller AD, Baric RS, Alter G, Sorger PK, Estes JD, Andersen H, Lewis MG, Barouch DH. Chandrashekar A, et al. Among authors: Alter G. Science. 2020 May 20:eabc4776. doi: 10.1126/science.abc4776. Online ahead of print. Science. 2020. PMID: 32434946 Free PMC article.
DNA vaccine protection against SARS-CoV-2 in rhesus macaques.
Yu J, Tostanoski LH, Peter L, Mercado NB, McMahan K, Mahrokhian SH, Nkolola JP, Liu J, Li Z, Chandrashekar A, Martinez DR, Loos C, Atyeo C, Fischinger S, Burke JS, Slein MD, Chen Y, Zuiani A, N Lelis FJ, Travers M, Habibi S, Pessaint L, Van Ry A, Blade K, Brown R, Cook A, Finneyfrock B, Dodson A, Teow E, Velasco J, Zahn R, Wegmann F, Bondzie EA, Dagotto G, Gebre MS, He X, Jacob-Dolan C, Kirilova M, Kordana N, Lin Z, Maxfield LF, Nampanya F, Nityanandam R, Ventura JD, Wan H, Cai Y, Chen B, Schmidt AG, Wesemann DR, Baric RS, Alter G, Andersen H, Lewis MG, Barouch DH. Yu J, et al. Among authors: Alter G. Science. 2020 May 20:eabc6284. doi: 10.1126/science.abc6284. Online ahead of print. Science. 2020. PMID: 32434945 Free PMC article.
Co-immunization of DNA and Protein in the Same Anatomical Sites Induces Superior Protective Immune Responses against SHIV Challenge.
Felber BK, Lu Z, Hu X, Valentin A, Rosati M, Remmel CAL, Weiner JA, Carpenter MC, Faircloth K, Stanfield-Oakley S, Williams WB, Shen X, Tomaras GD, LaBranche CC, Montefiori D, Trinh HV, Rao M, Alam MS, Vandergrift NA, Saunders KO, Wang Y, Rountree W, Das J, Alter G, Reed SG, Aye PP, Schiro F, Pahar B, Dufour JP, Veazey RS, Marx PA, Venzon DJ, Shaw GM, Ferrari G, Ackerman ME, Haynes BF, Pavlakis GN. Felber BK, et al. Among authors: Alter G. Cell Rep. 2020 May 12;31(6):107624. doi: 10.1016/j.celrep.2020.107624. Cell Rep. 2020. PMID: 32402293 Free article.
Correction: ALVAC-HIV B/C candidate HIV vaccine efficacy dependent on neutralization profile of challenge virus and adjuvant dose and type.
Schifanella L, Barnett SW, Bissa M, Galli V, Doster MN, Vaccari M, Tomaras GD, Shen X, Phogat S, Pal R, Montefiori DC, LaBranche CC, Rao M, Trinh HV, Washington-Parks R, Liyanage NPM, Gorini G, Brown DR, Liang F, Loré K, Venzon DJ, Magnanelli W, Metrinko M, Kramer J, Breed M, Alter G, Ruprecht RM, Franchini G. Schifanella L, et al. Among authors: Alter G. PLoS Pathog. 2020 Apr 28;16(4):e1008531. doi: 10.1371/journal.ppat.1008531. eCollection 2020 Apr. PLoS Pathog. 2020. PMID: 32343743 Free PMC article.
Non-neutralizing Antibodies from a Marburg Infection Survivor Mediate Protection by Fc-Effector Functions and by Enhancing Efficacy of Other Antibodies.
Ilinykh PA, Huang K, Santos RI, Gilchuk P, Gunn BM, Karim MM, Liang J, Fouch ME, Davidson E, Parekh DV, Kimble JB, Pietzsch CA, Meyer M, Kuzmina NA, Zeitlin L, Saphire EO, Alter G, Crowe JE Jr, Bukreyev A. Ilinykh PA, et al. Among authors: Alter G. Cell Host Microbe. 2020 Apr 8:S1931-3128(20)30189-X. doi: 10.1016/j.chom.2020.03.025. Online ahead of print. Cell Host Microbe. 2020. PMID: 32320678
Distinct Human NK Cell Phenotypes and Functional Responses to Mycobacterium tuberculosis in Adults From TB Endemic and Non-endemic Regions.
Harris LD, Khayumbi J, Ongalo J, Sasser LE, Tonui J, Campbell A, Odhiambo FH, Ouma SG, Alter G, Gandhi NR, Day CL. Harris LD, et al. Among authors: Alter G. Front Cell Infect Microbiol. 2020 Mar 24;10:120. doi: 10.3389/fcimb.2020.00120. eCollection 2020. Front Cell Infect Microbiol. 2020. PMID: 32266170 Free PMC article.
Hinge length contributes to the phagocytic activity of HIV-specific IgG1 and IgG3 antibodies.
Chu TH, Crowley AR, Backes I, Chang C, Tay M, Broge T, Tuyishime M, Ferrari G, Seaman MS, Richardson SI, Tomaras GD, Alter G, Leib D, Ackerman ME. Chu TH, et al. Among authors: Alter G. PLoS Pathog. 2020 Feb 24;16(2):e1008083. doi: 10.1371/journal.ppat.1008083. eCollection 2020 Feb. PLoS Pathog. 2020. PMID: 32092122 Free PMC article.
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