Altered cytoplasmic maturation in rescued in vitro matured oocytes.
Hum Reprod. 2019.
PMID: 31119269
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Altered cytoplasmic maturation in rescued in vitro matured oocytes.
Hum Reprod. 2019 Jun 4;34(6):1095-1105. doi: 10.1093/humrep/dez052.
Hum Reprod. 2019.
PMID: 31119269
WHAT IS KNOWN ALREADY: In vitro maturation of denuded immature non-GV oocytes benefits cycles with poor in vivo MII oocyte collection, but maturation levels of non-GV oocytes are only scored by polar body extrusion. Since oocyte …
WHAT IS KNOWN ALREADY: In vitro maturation of denuded immature non-GV oocytes benefits cycles with poor in vivo …
PLD1 promotes spindle assembly and migration through regulating autophagy in mouse oocyte meiosis.
Autophagy. 2024 Jul;20(7):1616-1638. doi: 10.1080/15548627.2024.2333164. Epub 2024 Mar 27.
Autophagy. 2024.
PMID: 38513669
PLD1 has been implicated in cytoskeletal reorganization and vesicle trafficking in somatic cells; however, its function remains unclear in oocyte meiosis. Herein, we found PLD1 stably expresses in mouse oocytes meiosis, with direct interaction with spindle, RAB11A(+ …
PLD1 has been implicated in cytoskeletal reorganization and vesicle trafficking in somatic cells; however, its function remains unclear in …
Diethylstilbestrol exposure disrupts mouse oocyte meiotic maturation in vitro through affecting spindle assembly and chromosome alignment.
Chemosphere. 2020 Jun;249:126182. doi: 10.1016/j.chemosphere.2020.126182. Epub 2020 Feb 11.
Chemosphere. 2020.
PMID: 32078850
Nevertheless, the mechanism and toxicity of DES on oocyte meiotic maturation are largely unknown. Herein, we found that DES (40 muM) intervened in mouse oocyte maturation and first polar body extrusion (PBE) was decreased in vitro. ...How …
Nevertheless, the mechanism and toxicity of DES on oocyte meiotic maturation are largely unknown. Herein, we found that DES (4 …
Vitrification of Human Oocytes Before or After Rescue-IVM Does not Impair Maturation Kinetics but Induces Meiotic Spindle Alterations.
Reprod Sci. 2024 Sep;31(9):2625-2636. doi: 10.1007/s43032-024-01596-7. Epub 2024 May 21.
Reprod Sci. 2024.
PMID: 38773027
Free PMC article.
Cryopreservation of in vitro matured oocytes is still considered as an experimental alternative to mature oocyte vitrification after ovarian stimulation. ...Oocytes were divided into three groups: freshly in vitro …
Cryopreservation of in vitro matured oocytes is still considered as an experimental alternative to mature …
A Nuclear and Cytoplasmic Characterization of Bovine Oocytes Reveals That Cysteamine Partially Rescues the Embryo Development in a Model of Low Ovarian Reserve.
Animals (Basel). 2021 Jun 29;11(7):1936. doi: 10.3390/ani11071936.
Animals (Basel). 2021.
PMID: 34209664
Free PMC article.
Bovine ovaries were classified according to the antral follicle count (AFC), and the retrieved oocytes were processed immediately or matured in vitro. We observed alterations in several cellular processes, suggesting a multifactorial etiology of …
Bovine ovaries were classified according to the antral follicle count (AFC), and the retrieved oocytes were processed immediately or …
Follistatin Rescues Blastocyst Development of Poor Quality Porcine Cumulus-Oocyte Complexes by Delaying Meiotic Resumption With Decreased cGMP.
Reprod Sci. 2018 May;25(5):759-772. doi: 10.1177/1933719117725829. Epub 2017 Aug 28.
Reprod Sci. 2018.
PMID: 28845753
Mammalian oocytes resume maturation when removed from follicles and cultured in vitro. During folliculogenesis, oocytes are bathed in follicular fluid (FF), which provides an important and specialized microenvironment for oocyte competenc …
Mammalian oocytes resume maturation when removed from follicles and cultured in vitro. During folliculogenesis, …
Impaired oocyte quality induced by dehydroepiandrosterone is partially rescued by metformin treatment.
PLoS One. 2015 Mar 26;10(3):e0122370. doi: 10.1371/journal.pone.0122370. eCollection 2015.
PLoS One. 2015.
PMID: 25811995
Free PMC article.
After the model validation was completed, metaphase II (MII) oocytes were retrieved and subsequent analyses of oocyte quality were performed. DHEA-treated mice yielded fewer MII oocytes, which displayed decreased mtDNA copy number, ATP content, inner mitochon …
After the model validation was completed, metaphase II (MII) oocytes were retrieved and subsequent analyses of oocyte quality …
The C. elegans maternal-effect gene clk-2 is essential for embryonic development, encodes a protein homologous to yeast Tel2p and affects telomere length.
Development. 2001 Oct;128(20):4045-55. doi: 10.1242/dev.128.20.4045.
Development. 2001.
PMID: 11641227
Yet, virtually all phenotypes are fully maternally rescued. Embryonic development strictly requires the activity of maternal clk-2 during a narrow time window between oocyte maturation and the two- to four-cell embryonic stage. ...Tel2p has been reported to b …
Yet, virtually all phenotypes are fully maternally rescued. Embryonic development strictly requires the activity of maternal clk-2 du …
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