Alters SE - Search Results

1

Systemic depletion of L-cyst(e)ine with cyst(e)inase increases reactive oxygen species and suppresses tumor growth.

Cramer SL, Saha A, Liu J, Tadi S, Tiziani S, Yan W, Triplett K, Lamb C, Alters SE, Rowlinson S, Zhang YJ, Keating MJ, Huang P, DiGiovanni J, Georgiou G, Stone E. Cramer SL, et al. Among authors: alters se. Nat Med. 2017 Jan;23(1):120-127. doi: 10.1038/nm.4232. Epub 2016 Nov 21. Nat Med. 2017. PMID: 27869804 Free PMC article.

2

Preclinical safety and antitumor activity of the arginine-degrading therapeutic enzyme pegzilarginase, a PEGylated, cobalt-substituted recombinant human arginase 1.

Agnello G, Alters SE, Rowlinson SW. Agnello G, et al. Among authors: alters se. Transl Res. 2020 Mar;217:11-22. doi: 10.1016/j.trsl.2019.12.005. Epub 2019 Dec 27. Transl Res. 2020. PMID: 31954097

3

Human recombinant arginase enzyme reduces plasma arginine in mouse models of arginase deficiency.

Burrage LC, Sun Q, Elsea SH, Jiang MM, Nagamani SC, Frankel AE, Stone E, Alters SE, Johnson DE, Rowlinson SW, Georgiou G; Members of Urea Cycle Disorders Consortium; Lee BH. Burrage LC, et al. Among authors: alters se. Hum Mol Genet. 2015 Nov 15;24(22):6417-27. doi: 10.1093/hmg/ddv352. Epub 2015 Sep 10. Hum Mol Genet. 2015. PMID: 26358771 Free PMC article.

4

GLP2-2G-XTEN: a pharmaceutical protein with improved serum half-life and efficacy in a rat Crohn's. PLoS One. 2012; 7(11): e50630.

Alters SE, McLaughlin B, Spink B, Lachinyan T, Wang CW, Podust V, Schellenberger V, Stemmer WP. Alters SE, et al. PLoS One. 2013 Jun 10;8(6):10.1371/annotation/5c7138bd-5602-466d-8daf-e75e0b7d7fdb. doi: 10.1371/annotation/5c7138bd-5602-466d-8daf-e75e0b7d7fdb. Print 2013. PLoS One. 2013. PMID: 23762221 Free PMC article.

5

GLP2-2G-XTEN: a pharmaceutical protein with improved serum half-life and efficacy in a rat Crohn's disease model.

Alters SE, McLaughlin B, Spink B, Lachinyan T, Wang CW, Podust V, Schellenberger V, Stemmer WP. Alters SE, et al. PLoS One. 2012;7(11):e50630. doi: 10.1371/journal.pone.0050630. Epub 2012 Nov 26. PLoS One. 2012. PMID: 23189208 Free PMC article.

6

A novel long-acting human growth hormone fusion protein (VRS-317): enhanced in vivo potency and half-life.

Cleland JL, Geething NC, Moore JA, Rogers BC, Spink BJ, Wang CW, Alters SE, Stemmer WP, Schellenberger V. Cleland JL, et al. Among authors: alters se. J Pharm Sci. 2012 Aug;101(8):2744-54. doi: 10.1002/jps.23229. Epub 2012 Jun 7. J Pharm Sci. 2012. PMID: 22678811 Free PMC article.

7

Selective tumor targeting by the hypoxia-activated prodrug AQ4N blocks tumor growth and metastasis in preclinical models of pancreatic cancer.

Lalani AS, Alters SE, Wong A, Albertella MR, Cleland JL, Henner WD. Lalani AS, et al. Among authors: alters se. Clin Cancer Res. 2007 Apr 1;13(7):2216-25. doi: 10.1158/1078-0432.CCR-06-2427. Clin Cancer Res. 2007. PMID: 17404106

8

Enhancement of the efficacy of an antagonist of an extracellular receptor by attachment to the surface of a biocompatible carrier.

Wartchow CA, Alters SE, Garzone PD, Li L, Choi S, DeChene NE, Doede T, Huang L, Pease JS, Shen Z, Knox SJ, Cleland JL. Wartchow CA, et al. Among authors: alters se. Pharm Res. 2004 Oct;21(10):1880-5. doi: 10.1023/b:pham.0000045243.98010.b6. Pharm Res. 2004. PMID: 15553236

9

Immune systems biology: immunoprofiling of cells and molecules.

Kantor AB, Alters SE, Cheal K, Dietz LJ. Kantor AB, et al. Among authors: alters se. Biotechniques. 2004 Mar;36(3):520-4. doi: 10.2144/04363PF01. Biotechniques. 2004. PMID: 15038168 Free article.

10

Dendritic cells loaded with MART-1 peptide or infected with adenoviral construct are functionally equivalent in the induction of tumor-specific cytotoxic T lymphocyte responses in patients with melanoma.

Philip R, Alters SE, Brunette E, Ashton J, Gadea J, Yau J, Lebkowski J, Philip M. Philip R, et al. Among authors: alters se. J Immunother. 2000 Jan;23(1):168-76. doi: 10.1097/00002371-200001000-00020. J Immunother. 2000. PMID: 10687150

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