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CD1a selectively captures endogenous cellular lipids that broadly block T cell response.
Cotton RN, Wegrecki M, Cheng TY, Chen YL, Veerapen N, Le Nours J, Orgill DP, Pomahac B, Talbot SG, Willis R, Altman JD, de Jong A, Van Rhijn I, Clark RA, Besra GS, Ogg G, Rossjohn J, Moody DB. Cotton RN, et al. Among authors: altman jd. J Exp Med. 2021 Jul 5;218(7):e20202699. doi: 10.1084/jem.20202699. Epub 2021 May 7. J Exp Med. 2021. PMID: 33961028
Human skin is colonized by T cells that recognize CD1a independently of lipid.
Cotton RN, Cheng TY, Wegrecki M, Le Nours J, Orgill DP, Pomahac B, Talbot SG, Willis RA, Altman JD, de Jong A, Ogg G, Van Rhijn I, Rossjohn J, Clark RA, Moody DB. Cotton RN, et al. Among authors: altman jd. J Clin Invest. 2021 Jan 4;131(1):e140706. doi: 10.1172/JCI140706. J Clin Invest. 2021. PMID: 33393500 Free PMC article.
Schistosoma mansoni Infection Is Associated With a Higher Probability of Tuberculosis Disease in HIV-Infected Adults in Kenya.
McLaughlin TA, Nizam A, Hayara FO, Ouma GS, Campbell A, Khayumbi J, Ongalo J, Ouma SG, Shah NS, Altman JD, Kaushal D, Rengarajan J, Ernst JD, Blumberg HM, Waller LA, Gandhi NR, Day CL, Benkeser D. McLaughlin TA, et al. Among authors: altman jd. J Acquir Immune Defic Syndr. 2021 Feb 1;86(2):157-163. doi: 10.1097/QAI.0000000000002536. J Acquir Immune Defic Syndr. 2021. PMID: 33074856
Casting a wider net: Immunosurveillance by nonclassical MHC molecules.
D'Souza MP, Adams E, Altman JD, Birnbaum ME, Boggiano C, Casorati G, Chien YH, Conley A, Eckle SBG, Früh K, Gondré-Lewis T, Hassan N, Huang H, Jayashankar L, Kasmar AG, Kunwar N, Lavelle J, Lewinsohn DM, Moody B, Picker L, Ramachandra L, Shastri N, Parham P, McMichael AJ, Yewdell JW. D'Souza MP, et al. Among authors: altman jd. PLoS Pathog. 2019 Feb 21;15(2):e1007567. doi: 10.1371/journal.ppat.1007567. eCollection 2019 Feb. PLoS Pathog. 2019. PMID: 30789961 Free PMC article. Review.
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