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Fatty acids in cystic fibrosis.
Freedman SD, Shea JC, Blanco PG, Alvarez JG. Freedman SD, et al. Curr Opin Pulm Med. 2000 Nov;6(6):530-2. doi: 10.1097/00063198-200011000-00012. Curr Opin Pulm Med. 2000. PMID: 11100964 Review.
Evidence of increased flux to n-6 docosapentaenoic acid in phospholipids of pancreas from cftr-/- knockout mice.
Ollero M, Laposata M, Zaman MM, Blanco PG, Andersson C, Zeind J, Urman Y, Kent G, Alvarez JG, Freedman SD. Ollero M, et al. Metabolism. 2006 Sep;55(9):1192-200. doi: 10.1016/j.metabol.2006.05.002. Metabolism. 2006. PMID: 16919538
Oral docosahexaenoic acid given to pregnant mice increases the amount of surfactant in lung and amniotic fluid in preterm fetuses.
Blanco PG, Freedman SD, Lopez MC, Ollero M, Comen E, Laposata M, Alvarez JG. Blanco PG, et al. Am J Obstet Gynecol. 2004 May;190(5):1369-74. doi: 10.1016/j.ajog.2003.11.001. Am J Obstet Gynecol. 2004. PMID: 15167843
Association of cystic fibrosis with abnormalities in fatty acid metabolism.
Freedman SD, Blanco PG, Zaman MM, Shea JC, Ollero M, Hopper IK, Weed DA, Gelrud A, Regan MM, Laposata M, Alvarez JG, O'Sullivan BP. Freedman SD, et al. N Engl J Med. 2004 Feb 5;350(6):560-9. doi: 10.1056/NEJMoa021218. N Engl J Med. 2004. PMID: 14762183
Docosahexaenoic acid selectively augments muscarinic stimulation of epithelial Cl- secretion.
Del Castillo IC, Alvarez JG, Freedman SD, Ollero M, Claros L, Song JC, Yoo J, Matthews JB. Del Castillo IC, et al. J Surg Res. 2003 Apr;110(2):338-43. doi: 10.1016/s0022-4804(02)00092-6. J Surg Res. 2003. PMID: 12788663
Analysis of lipid abnormalities in CF mice.
Freedman SD, Blanco PG, Shea JC, Alvarez JG. Freedman SD, et al. Methods Mol Med. 2002;70:517-24. doi: 10.1385/1-59259-187-6:517. Methods Mol Med. 2002. PMID: 11917547 No abstract available.
Characterization of LPS-induced lung inflammation in cftr-/- mice and the effect of docosahexaenoic acid.
Freedman SD, Weinstein D, Blanco PG, Martinez-Clark P, Urman S, Zaman M, Morrow JD, Alvarez JG. Freedman SD, et al. J Appl Physiol (1985). 2002 May;92(5):2169-76. doi: 10.1152/japplphysiol.00927.2001. J Appl Physiol (1985). 2002. PMID: 11960971
A membrane lipid imbalance plays a role in the phenotypic expression of cystic fibrosis in cftr(-/-) mice.
Freedman SD, Katz MH, Parker EM, Laposata M, Urman MY, Alvarez JG. Freedman SD, et al. Proc Natl Acad Sci U S A. 1999 Nov 23;96(24):13995-4000. doi: 10.1073/pnas.96.24.13995. Proc Natl Acad Sci U S A. 1999. PMID: 10570187 Free PMC article.
Mechanisms to explain pancreatic dysfunction in cystic fibrosis.
Freedman SD, Blanco P, Shea JC, Alvarez JG. Freedman SD, et al. Med Clin North Am. 2000 May;84(3):657-64, x. doi: 10.1016/s0025-7125(05)70248-0. Med Clin North Am. 2000. PMID: 10872422 Review.
Nutritional effects on host response to lung infections with mucoid Pseudomonas aeruginosa in mice.
van Heeckeren AM, Schluchter M, Xue L, Alvarez J, Freedman S, St George J, Davis PB. van Heeckeren AM, et al. Infect Immun. 2004 Mar;72(3):1479-86. doi: 10.1128/iai.72.3.1479-1486.2004. Infect Immun. 2004. PMID: 14977953 Free PMC article.
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