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Irf5 deficiency in macrophages promotes beneficial adipose tissue expansion and insulin sensitivity during obesity.
Dalmas E, Toubal A, Alzaid F, Blazek K, Eames HL, Lebozec K, Pini M, Hainault I, Montastier E, Denis RG, Ancel P, Lacombe A, Ling Y, Allatif O, Cruciani-Guglielmacci C, André S, Viguerie N, Poitou C, Stich V, Torcivia A, Foufelle F, Luquet S, Aron-Wisnewsky J, Langin D, Clément K, Udalova IA, Venteclef N. Dalmas E, et al. Among authors: alzaid f. Nat Med. 2015 Jun;21(6):610-8. doi: 10.1038/nm.3829. Epub 2015 May 4. Nat Med. 2015. PMID: 25939064
Loss of the co-repressor GPS2 sensitizes macrophage activation upon metabolic stress induced by obesity and type 2 diabetes.
Fan R, Toubal A, Goñi S, Drareni K, Huang Z, Alzaid F, Ballaire R, Ancel P, Liang N, Damdimopoulos A, Hainault I, Soprani A, Aron-Wisnewsky J, Foufelle F, Lawrence T, Gautier JF, Venteclef N, Treuter E. Fan R, et al. Among authors: alzaid f. Nat Med. 2016 Jul;22(7):780-91. doi: 10.1038/nm.4114. Epub 2016 Jun 6. Nat Med. 2016. PMID: 27270589
The RBM14/CoAA-interacting, long intergenic non-coding RNA Paral1 regulates adipogenesis and coactivates the nuclear receptor PPARγ.
Firmin FF, Oger F, Gheeraert C, Dubois-Chevalier J, Vercoutter-Edouart AS, Alzaid F, Mazuy C, Dehondt H, Alexandre J, Derudas B, Dhalluin Q, Ploton M, Berthier A, Woitrain E, Lefebvre T, Venteclef N, Pattou F, Staels B, Eeckhoute J, Lefebvre P. Firmin FF, et al. Among authors: alzaid f. Sci Rep. 2017 Oct 26;7(1):14087. doi: 10.1038/s41598-017-14570-y. Sci Rep. 2017. PMID: 29075020 Free PMC article. Clinical Trial.
Functional and phenotypical analysis of IL-6-secreting CD4+ T cells in human adipose tissue.
de Jong AJ, Pollastro S, Kwekkeboom JC, Andersen SN, Dorjée AL, Bakker AM, Alzaid F, Soprani A, Nelissen RGHH, Mullers JB, Venteclef N, de Vries N, Kloppenburg M, Toes REM, Ioan-Facsinay A. de Jong AJ, et al. Among authors: alzaid f. Eur J Immunol. 2018 Mar;48(3):471-481. doi: 10.1002/eji.201747037. Epub 2018 Jan 29. Eur J Immunol. 2018. PMID: 29283192 Free PMC article.
Genetic deficiency of indoleamine 2,3-dioxygenase promotes gut microbiota-mediated metabolic health.
Laurans L, Venteclef N, Haddad Y, Chajadine M, Alzaid F, Metghalchi S, Sovran B, Denis RGP, Dairou J, Cardellini M, Moreno-Navarrete JM, Straub M, Jegou S, McQuitty C, Viel T, Esposito B, Tavitian B, Callebert J, Luquet SH, Federici M, Fernandez-Real JM, Burcelin R, Launay JM, Tedgui A, Mallat Z, Sokol H, Taleb S. Laurans L, et al. Among authors: alzaid f. Nat Med. 2018 Aug;24(8):1113-1120. doi: 10.1038/s41591-018-0060-4. Epub 2018 Jun 25. Nat Med. 2018. PMID: 29942089
45 results