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The following terms were not found in PubMed: peptide+GSK-3beta, pathway+SH-SY5Y, cells+tanshinone, IIA+tau
Page 1
The relationship of soluble tau species with Alzheimer's disease amyloid plaque removal and tau pathology.
McDade EM, Barthélemy NR, Wang G, Li Y, Cao Y, Gordon B, Benzinger TLS, Clifford D, Goate AM, Renton AE, Hassenstab J, Llibre-Guerra JJ, Perrin RJ, Xiong C, Cruchaga C, Mummery CJ, Berman SB, Lah J, Roberson ED, Van Dyck C, Gauthier S, Masters CL, Masellis M, Bittner T, Yaari R, Chhatwal J, Chrem P, Brooks W, Suzuki K, Levin JJ, Jucker M, Ringman J, Wallon D, Ikeuchi T, Lee JH, Roh JH, Schofield P, Fox NC, Ryan NS, Vöglein J, Karch C, Ibáñez L, Day GS, Sánchez-Valle R, Daniels A, Morris JC, Supnet-Bell C, Levey AI, Bateman RJ; DIAN‐TU Study Team and DIAN Obs Team. McDade EM, et al. Alzheimers Dement. 2025 Sep;21(9):e70689. doi: 10.1002/alz.70689. Alzheimers Dement. 2025. PMID: 40985290 Free PMC article. Clinical Trial.
BACKGROUND: Tau-derived cerebrospinal fluid (CSF) biomarkers correlate with amyloid-beta (Abeta) plaques or tau tangles in Alzheimer's disease (AD). This study assessed the effects of long-term anti-Abeta antibodies on amyloid plaques, tau tangles, and …
BACKGROUND: Tau-derived cerebrospinal fluid (CSF) biomarkers correlate with amyloid-beta (Abeta) plaques or tau tangles in Alzheim …
Cognitive Decline in Preclinical Alzheimer's Disease: Amyloid-Beta versus Tauopathy.
Huber CM, Yee C, May T, Dhanala A, Mitchell CS. Huber CM, et al. J Alzheimers Dis. 2018;61(1):265-281. doi: 10.3233/JAD-170490. J Alzheimers Dis. 2018. PMID: 29154274 Free PMC article. Review.
We perform a large-scale meta-analysis of 51 peer-reviewed 3xTg-AD mouse publications to compare Alzheimer's disease (AD) quantitative clinical outcome measures, including amyloid-beta (Abeta), total tau, and phosphorylated tau (pTau), with cog …
We perform a large-scale meta-analysis of 51 peer-reviewed 3xTg-AD mouse publications to compare Alzheimer's disease ( …
Use of curcumin in diagnosis, prevention, and treatment of Alzheimer's disease.
Chen M, Du ZY, Zheng X, Li DL, Zhou RP, Zhang K. Chen M, et al. Neural Regen Res. 2018 Apr;13(4):742-752. doi: 10.4103/1673-5374.230303. Neural Regen Res. 2018. PMID: 29722330 Free PMC article. Review.
This review summarizes and describes the use of curcumin in diagnosis, prevention, and treatment of Alzheimer's disease. For diagnosis of Alzheimer's disease, amyloid-beta and highly phosphorylated tau protein are the …
This review summarizes and describes the use of curcumin in diagnosis, prevention, and treatment of Alzheimer's disease …
Plasma biomarker progression across the Alzheimer's disease amyloid beta and tau positron emission tomography trajectories.
Cánovas R, Fowler CJ, Feizpour A, Dóre V, Bourgeat P, Saad ZS, Triana-Baltzer G, Kolb HC, Vandijck M, Kollmorgen G, Quijano-Rubio C, Fripp J, Laws S, Bannon AW, Blennow K, Zetterberg H, Rainey-Smith S, Mathotaarachchi S, Rowe CC, Masters CL, Doecke JD; AIBL Research Group. Cánovas R, et al. Alzheimers Dement. 2026 Feb;22(2):e71145. doi: 10.1002/alz.71145. Alzheimers Dement. 2026. PMID: 41664541 Free PMC article.
INTRODUCTION: With increased uptake in disease-modifying treatments for amyloid beta (Abeta) removal, it is important to measure performance of highly sensitive plasma biomarkers to detect the presence of Abeta and tau in cognitively impaired populations. ...RESULTS …
INTRODUCTION: With increased uptake in disease-modifying treatments for amyloid beta (Abeta) removal, it is important to measu …
Regulation of neuroinflammation in Alzheimer's disease via nanoparticle-loaded phytocompounds with anti-inflammatory and autophagy-inducing properties.
Nayak V, Patra S, Rout S, Jena AB, Sharma R, Pattanaik KP, Singh J, Pandey SS, Singh RP, Majhi S, Singh KR, Kerry RG. Nayak V, et al. Phytomedicine. 2024 Jan;122:155150. doi: 10.1016/j.phymed.2023.155150. Epub 2023 Oct 15. Phytomedicine. 2024. PMID: 37944239
BACKGROUND: Alzheimer's disease (AD) is characterized by neuroinflammation linked to amyloid beta (Abeta) aggregation and phosphorylated tau (tau) protein in neurofibrillary tangles (NFTs). ...METHODS: Inclusion criteria involve selecting recent …
BACKGROUND: Alzheimer's disease (AD) is characterized by neuroinflammation linked to amyloid beta (Abeta) aggreg …
CSF proteomic profiling with amyloid and tau pathology identifies distinctive sex-specific alteration of multiple proteins involved in Alzheimer's disease.
Do AN, Song S, Ali M, Timsina J, Wang L, Western D, Liu M, Sanford J, Rosende-Roca M, Boada M, Puerta R, Wilson EN, Ruiz A, Pastor P; Alzheimer's Disease Neuroimaging Initiative (ADNI); Wyss-Coray T, Cruchaga C, Sung YJ. Do AN, et al. Alzheimers Dement. 2026 Jan;22(1):e71063. doi: 10.1002/alz.71063. Alzheimers Dement. 2026. PMID: 41505229 Free PMC article.
INTRODUCTION: In Alzheimer's disease (AD), females have higher prevalence and faster progression, but sex-specific molecular findings in AD are limited. METHODS: We comprehensively examined 6162 proteins in cerebrospinal fluid (CSF) from 2496 participants to …
INTRODUCTION: In Alzheimer's disease (AD), females have higher prevalence and faster progression, but sex-specific mole …
GSK-3alpha regulates production of Alzheimer's disease amyloid-beta peptides.
Phiel CJ, Wilson CA, Lee VM, Klein PS. Phiel CJ, et al. Nature. 2003 May 22;423(6938):435-9. doi: 10.1038/nature01640. Nature. 2003. PMID: 12761548
Alzheimer's disease is associated with increased production and aggregation of amyloid-beta (Abeta) peptides. ...The target of lithium in this setting is GSK-3alpha, which is required for maximal processing of APP. Since GSK-3 also phosphorylates …
Alzheimer's disease is associated with increased production and aggregation of amyloid-beta (Abeta) peptides. .. …
Butyrate Regulates the Blood-Brain Barrier Transport and Intraendothelial Accumulation of Alzheimer's Disease Amyloid-Beta Peptides.
Veerareddy V, Wang Z, Kashyap PC, Kandimalla KK. Veerareddy V, et al. Mol Pharm. 2026 Jul 6;23(7):3529-3540. doi: 10.1021/acs.molpharmaceut.5c01594. Epub 2026 May 21. Mol Pharm. 2026. PMID: 42166642
Alzheimer's disease (AD) is characterized by the pathological deposition of amyloid beta (Abeta) peptides as amyloid plaques and by cerebrovascular dysfunction, both of which drive AD progression. ...The roles of insulin signaling nodes, including AKT, …
Alzheimer's disease (AD) is characterized by the pathological deposition of amyloid beta (Abeta) peptides as amy …
Apolipoprotein E4 as a Novel Treatment Target for Alzheimer's Disease.
Jervies JL, King SP, Suphioglu C. Jervies JL, et al. Cell Physiol Biochem. 2021 Dec 15;55(6):773-783. doi: 10.33594/000000475. Cell Physiol Biochem. 2021. PMID: 34907696 Free article.
The importance of Alzheime's Disease (AD) research has never been greater from a worldwide perspective with the disease becoming increasingly prevalent with life expectancy on the rise. ...This is due to ApoE4's ability to not only increase amyloid …
The importance of Alzheime's Disease (AD) research has never been greater from a worldwide perspective with the dise …
Differential regulation of insulin signalling by monomeric and oligomeric amyloid beta-peptide.
Molina-Fernández R, Picón-Pagès P, Barranco-Almohalla A, Crepin G, Herrera-Fernández V, García-Elías A, Fanlo-Ucar H, Fernàndez-Busquets X, García-Ojalvo J, Oliva B, Muñoz FJ. Molina-Fernández R, et al. Brain Commun. 2022 Sep 24;4(5):fcac243. doi: 10.1093/braincomms/fcac243. eCollection 2022. Brain Commun. 2022. PMID: 36267327 Free PMC article.
Alzheimer's disease and Type 2 diabetes are pathological processes associated to ageing. ...Regarding Alzheimer's disease, amyloid beta-peptide aggregation into beta-sheets is the main hallmark of Alzheimer' …
Alzheimer's disease and Type 2 diabetes are pathological processes associated to ageing. ...Regarding Alzheimer' …
33 results