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A SETD2-CDK1-lamin axis maintains nuclear morphology and genome stability.
Khan A, Zhang C, Nguyen PG, Metts JM, Collins LC, Jain K, Mills CA, Vlach L, Li K, Brademeyer AL, Bowman BM, Major MB, Aubé J, Herring LE, Rathmell WK, Mason FM, Davis IJ, Zhang Q, Strahl BD. Khan A, et al. Among authors: brademeyer al. Nat Cell Biol. 2025 Aug;27(8):1327-1341. doi: 10.1038/s41556-025-01723-9. Epub 2025 Aug 11. Nat Cell Biol. 2025. PMID: 40789955 Free PMC article.
SETD2 maintains nuclear lamina stability to safeguard the genome.
Khan A, Metts JM, Collins LC, Mills CA, Li K, Brademeyer AL, Bowman BM, Major MB, Aubé J, Herring LE, Davis IJ, Strahl BD. Khan A, et al. Among authors: brademeyer al. bioRxiv [Preprint]. 2023 Sep 28:2023.09.28.560032. doi: 10.1101/2023.09.28.560032. bioRxiv. 2023. Update in: Nat Cell Biol. 2025 Aug;27(8):1327-1341. doi: 10.1038/s41556-025-01723-9. PMID: 37808753 Free PMC article. Updated. Preprint.