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Targeted intraceptor nanoparticle therapy reduces angiogenesis and fibrosis in primate and murine macular degeneration.
Luo L, Zhang X, Hirano Y, Tyagi P, Barabás P, Uehara H, Miya TR, Singh N, Archer B, Qazi Y, Jackman K, Das SK, Olsen T, Chennamaneni SR, Stagg BC, Ahmed F, Emerson L, Zygmunt K, Whitaker R, Mamalis C, Huang W, Gao G, Srinivas SP, Krizaj D, Baffi J, Ambati J, Kompella UB, Ambati BK. Luo L, et al. Among authors: ambati bk, ambati j. ACS Nano. 2013 Apr 23;7(4):3264-75. doi: 10.1021/nn305958y. Epub 2013 Mar 20. ACS Nano. 2013. PMID: 23464925 Free PMC article.
Photoreceptor avascular privilege is shielded by soluble VEGF receptor-1.
Luo L, Uehara H, Zhang X, Das SK, Olsen T, Holt D, Simonis JM, Jackman K, Singh N, Miya TR, Huang W, Ahmed F, Bastos-Carvalho A, Le YZ, Mamalis C, Chiodo VA, Hauswirth WW, Baffi J, Lacal PM, Orecchia A, Ferrara N, Gao G, Young-Hee K, Fu Y, Owen L, Albuquerque R, Baehr W, Thomas K, Li DY, Chalam KV, Shibuya M, Grisanti S, Wilson DJ, Ambati J, Ambati BK. Luo L, et al. Among authors: ambati bk, ambati j. Elife. 2013 Jun 18;2:e00324. doi: 10.7554/eLife.00324. Elife. 2013. PMID: 23795287 Free PMC article.
Targeted Intraceptor Nanoparticle for Neovascular Macular Degeneration: Preclinical Dose Optimization and Toxicology Assessment.
Zhang X, Bohner A, Bhuvanagiri S, Uehara H, Upadhyay AK, Emerson LL, Bondalapati S, Muddana SK, Fang D, Li M, Sandhu Z, Hussain A, Carroll LS, Tiem M, Archer B, Kompella U, Patil R, Ambati BK. Zhang X, et al. Among authors: ambati bk. Mol Ther. 2017 Jul 5;25(7):1606-1615. doi: 10.1016/j.ymthe.2017.01.014. Epub 2017 Feb 22. Mol Ther. 2017. PMID: 28236576 Free PMC article.
Anti-SPARC oligopeptide inhibits laser-induced CNV in mice.
Uehara H, Luo L, Simonis J, Singh N, Taylor EW, Ambati BK. Uehara H, et al. Among authors: ambati bk. Vision Res. 2010 Mar 31;50(7):674-9. doi: 10.1016/j.visres.2009.12.003. Epub 2009 Dec 22. Vision Res. 2010. PMID: 20005890 Free PMC article.
147 results