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McCune-Albright syndrome - a case report with café-au-lait lesion transmission electron microscopy.
Garcia Neto V, de Almeida HL Jr, Lorea CF, Jorge VM, de Almeida AL. Garcia Neto V, et al. An Bras Dermatol. 2021 Nov 25:S0365-0596(21)00269-5. doi: 10.1016/j.abd.2021.09.002. Online ahead of print. An Bras Dermatol. 2021. PMID: 34839987 Free article.
Light microscopy showed increased melanin pigment with HE staining. Immunohistochemistry with melanocytic markers (HMB-45 and Melan-A) revealed a normal number of melanocytes. Transmission electron microscopy demonstrated normal epidermal structures, such as desmosomes, cy …
Light microscopy showed increased melanin pigment with HE staining. Immunohistochemistry with melanocytic markers (HMB-45 and Melan-A …
Preventive Effect of M. cochinchinensis on Melanogenesis via Tyrosinase Activity Inhibition and p-PKC Signaling in Melan-A Cell.
Kim J, Hong SC, Lee EH, Lee JW, Yang SH, Kim JC. Kim J, et al. Nutrients. 2021 Oct 29;13(11):3894. doi: 10.3390/nu13113894. Nutrients. 2021. PMID: 34836147 Free PMC article.
This study aimed to determine whether M. cochinchinensis extracts inhibit melanin synthesis in melan-A cells by inhibiting tyrosinase activity and p-PKC signaling. M. cochinchinensis was divided into pulp and aril and extracted under various conditions, and it was confirme …
This study aimed to determine whether M. cochinchinensis extracts inhibit melanin synthesis in melan-A cells by inhibiting tyrosinase …
Pseudoalteromone A, a Ubiquinone Derivative from Marine Pseudoalteromonas spp., Suppresses Melanogenesis.
Lim SJ, Min DJ, Kim S, Lee J, Lee ES, Kim H, Cho SY, Beak HS, Lee CS, Nam SJ, Ko J. Lim SJ, et al. Mar Drugs. 2021 Oct 28;19(11):612. doi: 10.3390/md19110612. Mar Drugs. 2021. PMID: 34822483 Free PMC article.
An ubiquinone derivative, pseudoalteromone A (1), has been isolated from two marine-derived Pseudoalteromonas spp., APmarine002 and ROA-050, and its anti-melanogenesis activity was investigated. The anti-melanogenic capacity of pseudoalteromone A was demonstrated by assess …
An ubiquinone derivative, pseudoalteromone A (1), has been isolated from two marine-derived Pseudoalteromonas spp., APmarine002 and R …
Intracranial mesenchymal tumors with FET-CREB fusion are composed of at least two epigenetic subgroups distinct from meningioma and extracranial sarcomas.
Sloan EA, Gupta R, Koelsche C, Chiang J, Villanueva-Meyer JE, Alexandrescu S, Eschbacher JM, Wang W, Mafra M, Ud Din N, Carr-Boyd E, Watson M, Punsoni M, Oviedo A, Gilani A, Kleinschmidt-DeMasters BK, Coss DJ, Lopes MB, Reddy A, Mueller S, Cho SJ, Horvai AE, Lee JC, Pekmezci M, Tihan T, Bollen AW, Rodriguez FJ, Ellison DW, Perry A, von Deimling A, Chang SM, Berger MS, Solomon DA. Sloan EA, et al. Brain Pathol. 2021 Nov 25:e13037. doi: 10.1111/bpa.13037. Online ahead of print. Brain Pathol. 2021. PMID: 34821426
The first subgroup (Group A, 16 tumors) clustered nearest to but independent of solitary fibrous tumor and AFH of extracranial soft tissue, whereas the second epigenetic subgroup (Group B, 4 tumors) clustered nearest to but independent of CCS and also lacked expression of melanoc …
The first subgroup (Group A, 16 tumors) clustered nearest to but independent of solitary fibrous tumor and AFH of extracranial soft tissue, …
Primary pleomorphic liposarcoma of the liver: a case report and literature review.
Terunuma Y, Takahashi K, Doi M, Shimomura O, Miyazaki Y, Furuya K, Moue S, Owada Y, Ogawa K, Ohara Y, Akashi Y, Hashimoto S, Enomoto T, Oda T. Terunuma Y, et al. Surg Case Rep. 2021 Nov 19;7(1):244. doi: 10.1186/s40792-021-01322-4. Surg Case Rep. 2021. PMID: 34797454 Free PMC article.
Immunohistochemically, the tumor cells were diffusely positive for vimentin and focally positive for CD34 and alpha-SMA; lipoblasts were focally positive for S-100. Tumor cells were nonreactive for SF-1, inhibin alpha, desmin, HHF35, HMB45, Melan A, MITF, c-kit, DOG …
Immunohistochemically, the tumor cells were diffusely positive for vimentin and focally positive for CD34 and alpha-SMA; lipoblasts were foc …
Oral histiocytic sarcoma in a cat with mandibular invasion and regional lymph node metastasis.
Ruppert SL, Ferguson SH, Struthers JD, Jones TL. Ruppert SL, et al. JFMS Open Rep. 2021 Nov 9;7(2):20551169211058044. doi: 10.1177/20551169211058044. eCollection 2021 Jul-Dec. JFMS Open Rep. 2021. PMID: 34777847 Free PMC article.
Immunohistochemistry performed during the postmortem examination found that neoplastic cells were positive for Iba-1, CD18 and CD204, and negative for MUM-1, S100, Melan-A and E-cadherin, favoring a diagnosis of oral histiocytic sarcoma. ...
Immunohistochemistry performed during the postmortem examination found that neoplastic cells were positive for Iba-1, CD18 and CD204, …
Renal cell tumor with sex-cord/gonadoblastoma-like features: analysis of 6 cases.
Wang G, Amin MB, Grossmann P, Ptáková N, Hayes M, Hartmann A, Agaimy A, Lopez JI, Michal M, Hes O. Wang G, et al. Virchows Arch. 2021 Nov 13. doi: 10.1007/s00428-021-03235-x. Online ahead of print. Virchows Arch. 2021. PMID: 34775513
Cathepsin K and AMACR were variably positive. Tumors were negative for HMB45, Melan A, TFE3, SF1, inhibin, calretinin, ER, PR, CD117, OCT3/4, SALL4, ALK, and WT1. ...
Cathepsin K and AMACR were variably positive. Tumors were negative for HMB45, Melan A, TFE3, SF1, inhibin, calretinin, ER, PR, CD117, …
Eosinophilic solid cystic renal cell carcinoma: A series of 3 cases elucidating the spectrum of morphological and clinical features of an emerging new entity.
Sakhadeo U, Yadav SC, Bakshi GK, Prakash G, Katdare A, Menon S, Desai SB. Sakhadeo U, et al. Indian J Urol. 2021 Oct-Dec;37(4):350-354. doi: 10.4103/iju.iju_217_21. Epub 2021 Oct 1. Indian J Urol. 2021. PMID: 34759528 Free PMC article.
On immunohistochemistry, all the three cases showed a unique CK20+/alpha-methyl-acyl-CoA-racemase + immunophenotype. Melan-A was focally positive in Case 2. Cytokeratin 7 was focally but strongly positive in Case 3. ...
On immunohistochemistry, all the three cases showed a unique CK20+/alpha-methyl-acyl-CoA-racemase + immunophenotype. Melan-A was foca …
Primary Clear Cell Sarcoma of the Lung: a Case Report.
Hamouri S, Matalka I, Yaghan R, Al-Hussaini M, Jaber OI, AlQudah M, Al-Ahmad BH, Marji R, Matalka M, Hecker E. Hamouri S, et al. Med Arch. 2021 Aug;75(4):313-316. doi: 10.5455/medarh.2021.75.313-316. Med Arch. 2021. PMID: 34759454 Free PMC article.
The postoperative histological examination, immunohistochemical findings including positive staining for S-100, HMB-45, and Melan-A, and positive FISH study for EWSR1 gene rearrangements supported the diagnosis of CCSST originating primarily in the major fissure of left th …
The postoperative histological examination, immunohistochemical findings including positive staining for S-100, HMB-45, and Melan-A, …
Adrenocortical Cancer: A 20-Year Experience of a Single Referral Center in Prognosis and Outcomes.
Parianos C, Kyriakopoulos G, Kostakis ID, Nasiri-Ansari N, Aggeli C, Dimitriadi A, Angelousi A, Papavassiliou AG, Kaltsas GA, Zografos G, Kassi E. Parianos C, et al. Horm Metab Res. 2021 Nov;53(11):709-716. doi: 10.1055/a-1666-9026. Epub 2021 Nov 5. Horm Metab Res. 2021. PMID: 34740271
The male to female ratio was 1:1.37. The median age at diagnosis was 55.5 years (IQR 19-77). The median size of ACCs was 9 cm (IQR 3.5-22 cm) and the median weight 127 g (IQR 18-1400 g). The median follow up period was 18 months (IQR 1-96). Ki67 varied from&l …
The male to female ratio was 1:1.37. The median age at diagnosis was 55.5 years (IQR 19-77). The median size of ACCs was 9 cm …
2,870 results