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Year Number of Results
2006 1
2007 2
2008 1
2010 2
2011 2
2012 4
2013 4
2014 6
2015 3
2016 1
2017 3
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2020 2
2021 4
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Page 1
Discovery of an LSD1 PROTAC degrader.
Hosseini A, Qiu X, Xiong Y, Chiang KHN, Catlett J, Kaltheuner I, Deng Z, Ghosh S, Shi Y, Jin J. Hosseini A, et al. Proc Natl Acad Sci U S A. 2025 May 20;122(20):e2425812122. doi: 10.1073/pnas.2425812122. Epub 2025 May 14. Proc Natl Acad Sci U S A. 2025. PMID: 40366693 Free PMC article.
Epigenetic therapy induces transcription of inverted SINEs and ADAR1 dependency.
Mehdipour P, Marhon SA, Ettayebi I, Chakravarthy A, Hosseini A, Wang Y, de Castro FA, Loo Yau H, Ishak C, Abelson S, O'Brien CA, De Carvalho DD. Mehdipour P, et al. Among authors: hosseini a. Nature. 2020 Dec;588(7836):169-173. doi: 10.1038/s41586-020-2844-1. Epub 2020 Oct 21. Nature. 2020. PMID: 33087935
Chronic Viral Mimicry Induction following p53 Loss Promotes Immune Evasion.
Ishak CA, Marhon SA, Tchrakian N, Hodgson A, Loo Yau H, Gonzaga IM, Peralta M, Lungu IM, Gomez S, Liang SB, Shen SY, Chen R, Chen J, Chatterjee B, Wanniarachchi KN, Lee J, Zehrbach N, Hosseini A, Mehdipour P, Sun S, Solovyov A, Ettayebi I, Francis KE, He A, Wu T, Feng S, da Silva Medina T, Campos de Almeida F, Bayani J, Li J, MacDonald S, Wang Y, Garcia SS, Arthofer E, Diab N, Srivastava A, Austin PT, Sabatini PJB, Greenbaum BD, O'Brien CA, Shepherd TG, Tsao MS, Chiappinelli KB, Oza AM, Clarke BA, Rottapel R, Lheureux S, De Carvalho DD. Ishak CA, et al. Among authors: hosseini a. Cancer Discov. 2025 Apr 2;15(4):793-817. doi: 10.1158/2159-8290.CD-24-0094. Cancer Discov. 2025. PMID: 39776167 Free PMC article.
Perturbing LSD1 and WNT rewires transcription to synergistically induce AML differentiation.
Hosseini A, Dhall A, Ikonen N, Sikora N, Nguyen S, Shen Y, Amaral MLJ, Jiao A, Wallner F, Sergeev P, Lim Y, Yang Y, Vick B, Kawabata KC, Melnick A, Vyas P, Ren B, Jeremias I, Psaila B, Heckman CA, Blanco MA, Shi Y. Hosseini A, et al. Nature. 2025 Jun;642(8067):508-518. doi: 10.1038/s41586-025-08915-1. Epub 2025 Apr 16. Nature. 2025. PMID: 40240608 Free PMC article.
Lipid droplets and peroxisomes are co-regulated to drive lifespan extension in response to mono-unsaturated fatty acids.
Papsdorf K, Miklas JW, Hosseini A, Cabruja M, Morrow CS, Savini M, Yu Y, Silva-García CG, Haseley NR, Murphy LM, Yao P, de Launoit E, Dixon SJ, Snyder MP, Wang MC, Mair WB, Brunet A. Papsdorf K, et al. Among authors: hosseini a. Nat Cell Biol. 2023 May;25(5):672-684. doi: 10.1038/s41556-023-01136-6. Epub 2023 May 1. Nat Cell Biol. 2023. PMID: 37127715 Free PMC article.
Repeats mimic pathogen-associated patterns across a vast evolutionary landscape.
Šulc P, Di Gioacchino A, Solovyov A, Sun S, Martis S, Marhon SA, Lindholm HT, Chen R, Hosseini A, Jiang H, Ly BH, Taylor MS, Mehdipour P, Abdel-Wahab O, Rusk N, Vabret N, LaCava J, De Carvalho DD, Monasson R, Cocco S, Greenbaum BD. Šulc P, et al. Among authors: hosseini a. Cell Genom. 2025 Dec 10;5(12):101011. doi: 10.1016/j.xgen.2025.101011. Epub 2025 Sep 24. Cell Genom. 2025. PMID: 40997813 Free PMC article.
Decoding amyloid beta clearance systems at inner blood-retina barrier using three-dimensional ex vivo retinal imaging in Alzheimer's disease.
Wijesinghe P, Hosseini A, Campbell M, Tejpal S, Haynes J, Xi J, Mackenzie IR, Hirsch-Reinshagen V, Hsiung GR, Spiller BW, Wadzinski BE, Pham W, Matsubara JA. Wijesinghe P, et al. Among authors: hosseini a. Alzheimers Dement. 2025 Sep;21(9):e70592. doi: 10.1002/alz.70592. Alzheimers Dement. 2025. PMID: 41047467 Free PMC article.
60 results