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Deletion mapping defines different regions in 1p34.2-pter that may harbor genetic information related to human colorectal cancer.
Praml C, Finke LH, Herfarth C, Schlag P, Schwab M, Amler L. Praml C, et al. Among authors: amler l. Oncogene. 1995 Oct 5;11(7):1357-62. Oncogene. 1995. PMID: 7478557
Integrated genomic analysis of colorectal cancer progression reveals activation of EGFR through demethylation of the EREG promoter.
Qu X, Sandmann T, Frierson H Jr, Fu L, Fuentes E, Walter K, Okrah K, Rumpel C, Moskaluk C, Lu S, Wang Y, Bourgon R, Penuel E, Pirzkall A, Amler L, Lackner MR, Tabernero J, Hampton GM, Kabbarah O. Qu X, et al. Among authors: amler l. Oncogene. 2016 Dec 15;35(50):6403-6415. doi: 10.1038/onc.2016.170. Epub 2016 Jun 6. Oncogene. 2016. PMID: 27270421 Free PMC article.
Genomic instability in 1p and human malignancies.
Schwab M, Praml C, Amler LC. Schwab M, et al. Among authors: amler lc. Genes Chromosomes Cancer. 1996 Aug;16(4):211-29. doi: 10.1002/(SICI)1098-2264(199608)16:4<211::AID-GCC1>3.0.CO;2-0. Genes Chromosomes Cancer. 1996. PMID: 8875235 Review.
The DDX1 gene maps within 400 kbp 5' to MYCN and is frequently coamplified in human neuroblastoma.
Amler LC, Schürmann J, Schwab M. Amler LC, et al. Genes Chromosomes Cancer. 1996 Feb;15(2):134-7. doi: 10.1002/(SICI)1098-2264(199602)15:2<134::AID-GCC9>3.0.CO;2-4. Genes Chromosomes Cancer. 1996. PMID: 8834178
MYCN is retained in single copy at chromosome 2 band p23-24 during amplification in human neuroblastoma cells.
Corvi R, Amler LC, Savelyeva L, Gehring M, Schwab M. Corvi R, et al. Among authors: amler lc. Proc Natl Acad Sci U S A. 1994 Jun 7;91(12):5523-7. doi: 10.1073/pnas.91.12.5523. Proc Natl Acad Sci U S A. 1994. PMID: 8202521 Free PMC article.
A reciprocal translocation (1;15) (36.2;q24) in a neuroblastoma cell line is accompanied by DNA duplication and may signal the site of a putative tumor suppressor-gene.
Amler LC, Corvi R, Praml C, Savelyeva L, Le Paslier D, Schwab M. Amler LC, et al. Oncogene. 1995 Mar 16;10(6):1095-101. Oncogene. 1995. PMID: 7700634
Human homologue of a candidate for the Mom1 locus, the secretory type II phospholipase A2 (PLA2S-II), maps to 1p35-36.1/D1S199.
Praml C, Savelyeva L, Le Paslier D, Siracusa LD, Buchberg AM, Schwab M, Amler LC. Praml C, et al. Among authors: amler lc. Cancer Res. 1995 Dec 1;55(23):5504-6. Cancer Res. 1995. PMID: 7585622
The 1p deletion is not a reliable marker for the prognosis of patients with neuroblastoma.
Gehring M, Berthold F, Edler L, Schwab M, Amler LC. Gehring M, et al. Among authors: amler lc. Cancer Res. 1995 Nov 15;55(22):5366-9. Cancer Res. 1995. PMID: 7585602
Reciprocal translocation at 1p36.2/D1S160 in a neuroblastoma cell line: isolation of a YAC clone at the break.
Amler LC, Corvi R, Praml C, Savelyeva L, Le Paslier D, Schwab M. Amler LC, et al. Eur J Cancer. 1995;31A(4):527-30. doi: 10.1016/0959-8049(95)00064-p. Eur J Cancer. 1995. PMID: 7576959
Amplified N-myc in human neuroblastoma cells is often arranged as clustered tandem repeats of differently recombined DNA.
Amler LC, Schwab M. Amler LC, et al. Mol Cell Biol. 1989 Nov;9(11):4903-13. doi: 10.1128/mcb.9.11.4903. Mol Cell Biol. 1989. PMID: 2601700 Free PMC article.
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