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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1995 1
1996 2
1999 1
2001 1
2002 1
2004 1
2006 1
2008 2
2009 3
2010 1
2011 2
2013 1
2014 1
2016 2
2017 2
2018 1
2019 2
2020 4
2021 3
2022 7
2023 2
2024 0

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39 results

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Page 1
ISG15 and ISGylation in Human Diseases.
Mirzalieva O, Juncker M, Schwartzenburg J, Desai S. Mirzalieva O, et al. Cells. 2022 Feb 4;11(3):538. doi: 10.3390/cells11030538. Cells. 2022. PMID: 35159348 Free PMC article. Review.
Type I Interferons (IFNs) induce the expression of >500 genes, which are collectively called ISGs (IFN-stimulated genes). ...However, its IFN-dependent expression is aberrantly elevated or compromised in various human diseases, including multiple types of cancer, neurod
Type I Interferons (IFNs) induce the expression of >500 genes, which are collectively called ISGs (IFN-stimulated genes). ...Howev
Organelle-specific autophagy in inflammatory diseases: a potential therapeutic target underlying the quality control of multiple organelles.
Yao RQ, Ren C, Xia ZF, Yao YM. Yao RQ, et al. Autophagy. 2021 Feb;17(2):385-401. doi: 10.1080/15548627.2020.1725377. Epub 2020 Feb 12. Autophagy. 2021. PMID: 32048886 Free PMC article. Review.
Organelle-specific autophagy is one of the major subtypes of autophagy, selectively targeting different organelles for quality control. This type of autophagy includes mitophagy, pexophagy, reticulophagy (endoplasmic reticulum), ribophagy, lysophagy, and nucleophagy. ...In …
Organelle-specific autophagy is one of the major subtypes of autophagy, selectively targeting different organelles for quality control. This …
Treatment for sialorrhea (excessive saliva) in people with motor neuron disease/amyotrophic lateral sclerosis.
James E, Ellis C, Brassington R, Sathasivam S, Young CA. James E, et al. Cochrane Database Syst Rev. 2022 May 20;5(5):CD006981. doi: 10.1002/14651858.CD006981.pub3. Cochrane Database Syst Rev. 2022. PMID: 35593746 Free PMC article. Review.
BACKGROUND: Motor neuron disease (MND), also known as amyotrophic lateral sclerosis (ALS), is a progressive neurodegenerative condition that may cause dysphagia, as well as limb weakness, dysarthria, emotional lability, and respiratory failure. ...The trial p …
BACKGROUND: Motor neuron disease (MND), also known as amyotrophic lateral sclerosis (ALS), is a progressive neurodegene …
Adaptive Remodeling of the Neuromuscular Junction with Aging.
Deschenes MR, Flannery R, Hawbaker A, Patek L, Mifsud M. Deschenes MR, et al. Cells. 2022 Mar 29;11(7):1150. doi: 10.3390/cells11071150. Cells. 2022. PMID: 35406714 Free PMC article. Review.
This process, referred to as "sarcopenia", is considered a disease by itself, and it has been linked to a number of other serious maladies such as type II diabetes, osteoporosis, arthritis, cardiovascular disease, and even dementia. ...The NMJ also shows plasticity in resp …
This process, referred to as "sarcopenia", is considered a disease by itself, and it has been linked to a number of other serious maladies s …
Nuclear Ubiquitin-Proteasome Pathways in Proteostasis Maintenance.
Franić D, Zubčić K, Boban M. Franić D, et al. Biomolecules. 2021 Jan 4;11(1):54. doi: 10.3390/biom11010054. Biomolecules. 2021. PMID: 33406777 Free PMC article. Review.
Protein homeostasis, or proteostasis, is crucial for the functioning of a cell, as proteins that are mislocalized, present in excessive amounts, or aberrant due to misfolding or other type of damage can be harmful. Proteostasis includes attaining the correct protein struct …
Protein homeostasis, or proteostasis, is crucial for the functioning of a cell, as proteins that are mislocalized, present in excessive amou …
Ganglioside GM1 and the Central Nervous System.
Guo Z. Guo Z. Int J Mol Sci. 2023 May 31;24(11):9558. doi: 10.3390/ijms24119558. Int J Mol Sci. 2023. PMID: 37298512 Free PMC article. Review.
Its expression level, distribution pattern, and lipid composition are dependent upon cell and tissue type, developmental stage, and disease state, which suggests a potentially broad spectrum of functions of GM1 in various neurological and neuropathological processes. ...Ad …
Its expression level, distribution pattern, and lipid composition are dependent upon cell and tissue type, developmental stage, and d …
Polypharmacological Approaches for CNS Diseases: Focus on Endocannabinoid Degradation Inhibition.
Papa A, Pasquini S, Contri C, Gemma S, Campiani G, Butini S, Varani K, Vincenzi F. Papa A, et al. Cells. 2022 Jan 29;11(3):471. doi: 10.3390/cells11030471. Cells. 2022. PMID: 35159280 Free PMC article. Review.
The endocannabinoid system (ECS) is emerging as a particularly attractive therapeutic target in CNS disorders and neurodegenerative diseases including Parkinson's disease (PD), Alzheimer's disease (AD), Huntington's disease (HD), multiple sclerosis (MS), amyotrophic
The endocannabinoid system (ECS) is emerging as a particularly attractive therapeutic target in CNS disorders and neurodegenerative diseases …
How can we interpret the relationship between liquid-liquid phase separation and amyotrophic lateral sclerosis?
Kanekura K, Kuroda M. Kanekura K, et al. Lab Invest. 2022 Sep;102(9):912-918. doi: 10.1038/s41374-022-00791-x. Epub 2022 Apr 22. Lab Invest. 2022. PMID: 35459796 Free article. Review.
These inclusions are found in various neurodegenerative diseases such as Alzheimer's disease, amyotrophic lateral sclerosis (ALS), Huntington's disease, Parkinson's disease, and frontotemporal dementia (FTD). ...Still, the aggregates observed in neurodegenera …
These inclusions are found in various neurodegenerative diseases such as Alzheimer's disease, amyotrophic lateral sclerosis
Interleukin-1 Blockade: An Update on Emerging Indications.
Mistry A, Savic S, van der Hilst JCH. Mistry A, et al. BioDrugs. 2017 Jun;31(3):207-221. doi: 10.1007/s40259-017-0224-7. BioDrugs. 2017. PMID: 28497222 Review.
In other diseases, IL-1 has shown to be present in disease process but is not the central driving force of inflammation. In these conditions, including type 1 and 2 diabetes mellitus, acute coronary syndrome, amyotrophic lateral sclerosis, and several …
In other diseases, IL-1 has shown to be present in disease process but is not the central driving force of inflammation. In these conditions …
Regulation of Gut Microbiota and Metabolic Endotoxemia with Dietary Factors.
Fuke N, Nagata N, Suganuma H, Ota T. Fuke N, et al. Nutrients. 2019 Sep 23;11(10):2277. doi: 10.3390/nu11102277. Nutrients. 2019. PMID: 31547555 Free PMC article. Review.
It has been suggested to lead to chronic inflammation-related diseases such as obesity, type 2 diabetes mellitus, non-alcoholic fatty liver disease (NAFLD), pancreatitis, amyotrophic lateral sclerosis, and Alzheimer's disease. ...
It has been suggested to lead to chronic inflammation-related diseases such as obesity, type 2 diabetes mellitus, non-alcoholic fatty …
39 results