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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1990 1
1992 1
1993 1
1994 2
1995 1
1996 3
1997 1
1999 2
2000 2
2001 1
2003 3
2004 1
2005 1
2006 2
2007 3
2008 2
2009 1
2010 2
2011 8
2012 5
2013 5
2014 4
2015 2
2016 3
2017 4
2018 5
2019 6
2020 3
2021 4
2022 6
2023 3

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80 results

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Page 1
Update on genetics of amyotrophic lateral sclerosis.
Brenner D, Freischmidt A. Brenner D, et al. Curr Opin Neurol. 2022 Oct 1;35(5):672-677. doi: 10.1097/WCO.0000000000001093. Epub 2022 Aug 8. Curr Opin Neurol. 2022. PMID: 35942673 Review.
RECENT FINDINGS: Most recent disease gene discoveries constitute the candidate and risk genes SPTLC1 , KANK1 , CAV1 , HTT , and WDR7 , as well as seven novel risk loci. Cell type and functional enrichment analyses enlighten the genetic basis of selective motor neuron vulne …
RECENT FINDINGS: Most recent disease gene discoveries constitute the candidate and risk genes SPTLC1 , KANK1 , CAV1 , HTT , and WDR7 , as we …
Organelle-specific autophagy in inflammatory diseases: a potential therapeutic target underlying the quality control of multiple organelles.
Yao RQ, Ren C, Xia ZF, Yao YM. Yao RQ, et al. Autophagy. 2021 Feb;17(2):385-401. doi: 10.1080/15548627.2020.1725377. Epub 2020 Feb 12. Autophagy. 2021. PMID: 32048886 Free PMC article. Review.
Organelle-specific autophagy is one of the major subtypes of autophagy, selectively targeting different organelles for quality control. This type of autophagy includes mitophagy, pexophagy, reticulophagy (endoplasmic reticulum), ribophagy, lysophagy, and nucleophagy. ...In …
Organelle-specific autophagy is one of the major subtypes of autophagy, selectively targeting different organelles for quality control. This …
Astrocytic and microglial cells as the modulators of neuroinflammation in Alzheimer's disease.
Singh D. Singh D. J Neuroinflammation. 2022 Aug 17;19(1):206. doi: 10.1186/s12974-022-02565-0. J Neuroinflammation. 2022. PMID: 35978311 Free PMC article. Review.
However, chronic or uncontrolled inflammatory responses may lead to various neurodegenerative diseases, including Alzheimer's disease (AD), Parkinson's disease (PD), amyotrophic lateral sclerosis, and multiple sclerosis. These diseases have variable cl …
However, chronic or uncontrolled inflammatory responses may lead to various neurodegenerative diseases, including Alzheimer's disease (AD), …
Fatigue in healthy and diseased individuals.
Finsterer J, Mahjoub SZ. Finsterer J, et al. Am J Hosp Palliat Care. 2014 Aug;31(5):562-75. doi: 10.1177/1049909113494748. Epub 2013 Jul 26. Am J Hosp Palliat Care. 2014. PMID: 23892338 Review.
RESULTS: Fatigue is influenced by age, gender, physical condition, type of food, latency to last meal, mental status, psychological conditions, personality type, life experience, and the health status of an individual. ...Among neurological disorders, the prevalence …
RESULTS: Fatigue is influenced by age, gender, physical condition, type of food, latency to last meal, mental status, psychological c …
Treatment for sialorrhea (excessive saliva) in people with motor neuron disease/amyotrophic lateral sclerosis.
James E, Ellis C, Brassington R, Sathasivam S, Young CA. James E, et al. Cochrane Database Syst Rev. 2022 May 20;5(5):CD006981. doi: 10.1002/14651858.CD006981.pub3. Cochrane Database Syst Rev. 2022. PMID: 35593746 Free PMC article. Review.
BACKGROUND: Motor neuron disease (MND), also known as amyotrophic lateral sclerosis (ALS), is a progressive neurodegenerative condition that may cause dysphagia, as well as limb weakness, dysarthria, emotional lability, and respiratory failure. Since normal s …
BACKGROUND: Motor neuron disease (MND), also known as amyotrophic lateral sclerosis (ALS), is a progressive neurodegene …
Impaired autophagy and APP processing in Alzheimer's disease: The potential role of Beclin 1 interactome.
Salminen A, Kaarniranta K, Kauppinen A, Ojala J, Haapasalo A, Soininen H, Hiltunen M. Salminen A, et al. Prog Neurobiol. 2013 Jul-Aug;106-107:33-54. doi: 10.1016/j.pneurobio.2013.06.002. Epub 2013 Jul 1. Prog Neurobiol. 2013. PMID: 23827971 Review.
The accumulation of amyloid-beta-containing neuritic plaques and intracellular tau protein tangles are key histopathological hallmarks of Alzheimer's disease (AD). This type of pathology clearly indicates that the mechanisms of neuronal housekeeping and protein quality con …
The accumulation of amyloid-beta-containing neuritic plaques and intracellular tau protein tangles are key histopathological hallmarks of Al …
Rate of familial amyotrophic lateral sclerosis: a systematic review and meta-analysis.
Byrne S, Walsh C, Lynch C, Bede P, Elamin M, Kenna K, McLaughlin R, Hardiman O. Byrne S, et al. J Neurol Neurosurg Psychiatry. 2011 Jun;82(6):623-7. doi: 10.1136/jnnp.2010.224501. Epub 2010 Nov 3. J Neurol Neurosurg Psychiatry. 2011. PMID: 21047878 Review.
BACKGROUND: The population rate of familial amyotrophic lateral sclerosis (FALS) is frequently reported as 10%. ...Thirty-three papers were included in analysis and the rate of FALS for all studies was 4.6% (95% CI 3.9% to 5.5%). Restricting the …
BACKGROUND: The population rate of familial amyotrophic lateral sclerosis (FALS) is frequently reported as 10%. ...Thir …
Possible etiology and treatment of amyotrophic lateral sclerosis.
Holecek V, Rokyta R. Holecek V, et al. Neuro Endocrinol Lett. 2018 Feb;38(8):528-531. Neuro Endocrinol Lett. 2018. PMID: 29504729 Review.
Amyotrophic Lateral Sclerosis (ALS) is one of the most dangerous and least understood diseases with a pathophysiology that is still largely unknown. ...As concerns the pathogenesis of ALS, we discussed several phenomenon such as increased levels of specific s …
Amyotrophic Lateral Sclerosis (ALS) is one of the most dangerous and least understood diseases with a pathophysiology t …
Optineurin and amyotrophic lateral sclerosis.
Maruyama H, Kawakami H. Maruyama H, et al. Geriatr Gerontol Int. 2013 Jul;13(3):528-32. doi: 10.1111/ggi.12022. Epub 2012 Dec 26. Geriatr Gerontol Int. 2013. PMID: 23279185 Review.
Amyotrophic lateral sclerosis is a devastating disease, and thus it is important to identify the causative gene and resolve the mechanism of the disease. ...These findings strongly suggest that optineurin is involved in the pathogenesis of amyotrophic …
Amyotrophic lateral sclerosis is a devastating disease, and thus it is important to identify the causative gene and res …
The role of spirituality in people with amyotrophic lateral sclerosis and their caregivers: Scoping review.
Gonçalves F, Teixeira MI, Magalhães B. Gonçalves F, et al. Palliat Support Care. 2023 Oct;21(5):914-924. doi: 10.1017/S1478951522001511. Palliat Support Care. 2023. PMID: 36464916 Review.
BACKGROUND: There are few studies evaluating the role of spirituality and the role of spiritually integrated interventions in people with amyotrophic lateral sclerosis (PALS) and their caregivers. OBJECTIVES: A scoping review was conducted to examine the natu …
BACKGROUND: There are few studies evaluating the role of spirituality and the role of spiritually integrated interventions in people with …
80 results