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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1994 1
2006 2
2007 3
2010 3
2011 4
2012 2
2013 2
2014 6
2015 4
2016 4
2017 4
2018 5
2019 3
2020 7
2021 2
2022 7
2023 2
2024 0

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53 results

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Page 1
Mitochondria-associated membranes in aging and senescence: structure, function, and dynamics.
Janikiewicz J, Szymański J, Malinska D, Patalas-Krawczyk P, Michalska B, Duszyński J, Giorgi C, Bonora M, Dobrzyn A, Wieckowski MR. Janikiewicz J, et al. Cell Death Dis. 2018 Feb 28;9(3):332. doi: 10.1038/s41419-017-0105-5. Cell Death Dis. 2018. PMID: 29491385 Free PMC article. Review.
Recently, MAM have also been studied in the context of different pathologies, including Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis, type 2 diabetes mellitus and GM1-gangliosidosis. ...
Recently, MAM have also been studied in the context of different pathologies, including Alzheimer's disease, Parkinson's disease, amyotro
Rate of familial amyotrophic lateral sclerosis: a systematic review and meta-analysis.
Byrne S, Walsh C, Lynch C, Bede P, Elamin M, Kenna K, McLaughlin R, Hardiman O. Byrne S, et al. J Neurol Neurosurg Psychiatry. 2011 Jun;82(6):623-7. doi: 10.1136/jnnp.2010.224501. Epub 2010 Nov 3. J Neurol Neurosurg Psychiatry. 2011. PMID: 21047878 Review.
BACKGROUND: The population rate of familial amyotrophic lateral sclerosis (FALS) is frequently reported as 10%. ...METHOD: A Medline literature review identified all original articles reporting a rate of FALS. Studies were grouped according to the type
BACKGROUND: The population rate of familial amyotrophic lateral sclerosis (FALS) is frequently reported as 10%. ...METH …
Wolfram syndrome: MAMs' connection?
Delprat B, Maurice T, Delettre C. Delprat B, et al. Cell Death Dis. 2018 Mar 6;9(3):364. doi: 10.1038/s41419-018-0406-3. Cell Death Dis. 2018. PMID: 29511163 Free PMC article. Review.
Two types of WS are characterized so far and Wolfram syndrome type 2 is due to mutation in CISD2, a protein mostly expressed in MAMs. The aim of the present review is to collect evidences showing that WS is indeed a mitochondriopathy, with established MAM dysfunction, and …
Two types of WS are characterized so far and Wolfram syndrome type 2 is due to mutation in CISD2, a protein mostly expressed in MAMs. …
ADAMTS-4 in central nervous system pathologies.
Lemarchant S, Wojciechowski S, Vivien D, Koistinaho J. Lemarchant S, et al. J Neurosci Res. 2017 Sep;95(9):1703-1711. doi: 10.1002/jnr.24021. Epub 2017 Jan 13. J Neurosci Res. 2017. PMID: 28084617 Review.
ADAMTS-4 (a disintegrin and metalloproteinase with thrombospondin motifs type 4) is a metalloproteinase specialized in the degradation of chondroitin sulfate proteoglycans, contributing to cartilage breakdown during arthritis. ...Then, we discuss the contributions of ADAMT …
ADAMTS-4 (a disintegrin and metalloproteinase with thrombospondin motifs type 4) is a metalloproteinase specialized in the degradatio …
Selective Autophagy Receptors in Neuronal Health and Disease.
Conway O, Akpinar HA, Rogov VV, Kirkin V. Conway O, et al. J Mol Biol. 2020 Apr 3;432(8):2483-2509. doi: 10.1016/j.jmb.2019.10.013. Epub 2019 Oct 22. J Mol Biol. 2020. PMID: 31654670 Review.
Because of their unique morphological and functional specialization, cells of this type are sensitive to the stress caused by accumulation of misfolded proteins or damaged organelles. ...Like in human neurodegenerative diseases (NDDs)-Alzheimer's disease, Parkinson's disea …
Because of their unique morphological and functional specialization, cells of this type are sensitive to the stress caused by accumul …
Understanding and managing metabolic dysfunction in Amyotrophic Lateral Sclerosis.
Blasco H, Lanznaster D, Veyrat-Durebex C, Hergesheimer R, Vourch P, Maillot F, Andres CR, Pradat PF, Corcia P. Blasco H, et al. Expert Rev Neurother. 2020 Sep;20(9):907-919. doi: 10.1080/14737175.2020.1788389. Epub 2020 Jul 13. Expert Rev Neurother. 2020. PMID: 32583696 Review.
INTRODUCTION: Amyotrophic Lateral Sclerosis (ALS) is a fatal motor neuron disease that leads to death after a median survival of 36 months. ...EXPERT OPINION: The authors suggest that this is due to the insufficient knowledge of the relationship between the m …
INTRODUCTION: Amyotrophic Lateral Sclerosis (ALS) is a fatal motor neuron disease that leads to death after a median su …
A retrospective review of the progress in amyotrophic lateral sclerosis drug discovery over the last decade and a look at the latest strategies.
DeLoach A, Cozart M, Kiaei A, Kiaei M. DeLoach A, et al. Expert Opin Drug Discov. 2015 Oct;10(10):1099-118. doi: 10.1517/17460441.2015.1067197. Epub 2015 Aug 26. Expert Opin Drug Discov. 2015. PMID: 26307158 Review.
INTRODUCTION: Drug discovery for amyotrophic lateral sclerosis (ALS) has experienced a surge in clinical studies and remarkable preclinical milestones utilizing a variety of mutant superoxide dismutase 1 model systems. ...EXPERT OPINION: Valuable lessons from …
INTRODUCTION: Drug discovery for amyotrophic lateral sclerosis (ALS) has experienced a surge in clinical studies and re …
Singling out motor neurons in the age of single-cell transcriptomics.
Blum JA, Gitler AD. Blum JA, et al. Trends Genet. 2022 Sep;38(9):904-919. doi: 10.1016/j.tig.2022.03.016. Epub 2022 Apr 26. Trends Genet. 2022. PMID: 35487823 Free PMC article. Review.
Motor neurons are a remarkably powerful cell type in the central nervous system. They innervate and control the contraction of virtually every muscle in the body and their dysfunction underlies numerous neuromuscular diseases. ...
Motor neurons are a remarkably powerful cell type in the central nervous system. They innervate and control the contraction of virtua …
Does wild-type Cu/Zn-superoxide dismutase have pathogenic roles in amyotrophic lateral sclerosis?
Furukawa Y, Tokuda E. Furukawa Y, et al. Transl Neurodegener. 2020 Aug 19;9(1):33. doi: 10.1186/s40035-020-00209-y. Transl Neurodegener. 2020. PMID: 32811540 Free PMC article. Review.
Amyotrophic lateral sclerosis (ALS) is characterized by adult-onset progressive degeneration of upper and lower motor neurons. ...In order to search for evidence on misfolding and aggregation of wild-type SOD1 in vivo, we reviewed pathological studies
Amyotrophic lateral sclerosis (ALS) is characterized by adult-onset progressive degeneration of upper and lower motor n
Association between Galectin Levels and Neurodegenerative Diseases: Systematic Review and Meta-Analysis.
Ramos-Martínez E, Ramos-Martínez I, Sánchez-Betancourt I, Ramos-Martínez JC, Peña-Corona SI, Valencia J, Saucedo R, Almeida-Aguirre EKP, Cerbón M. Ramos-Martínez E, et al. Biomolecules. 2022 Jul 31;12(8):1062. doi: 10.3390/biom12081062. Biomolecules. 2022. PMID: 36008956 Free PMC article. Review.
Patients with Alzheimer's disease (AD), amyotrophic lateral sclerosis (ALD), and Parkinson's disease (PD) expressed higher levels of galectin-3. Patients with multiple sclerosis (MS) have higher levels of galectin-9. In conclusion, our meta-anal …
Patients with Alzheimer's disease (AD), amyotrophic lateral sclerosis (ALD), and Parkinson's disease (PD) expressed hig …
53 results