Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1978 1
1989 1
1993 1
1995 2
1997 3
1999 1
2000 4
2001 1
2002 1
2003 4
2004 3
2005 2
2006 2
2008 5
2009 1
2010 2
2011 6
2012 6
2013 6
2014 7
2015 4
2016 7
2017 7
2018 4
2019 5
2020 7
2021 8
2022 4
2023 5
2024 2

Text availability

Article attribute

Article type

Publication date

Search Results

103 results

Results by year

Filters applied: . Clear all
Page 1
Microglia-mediated neuroinflammation in neurodegenerative diseases.
Subhramanyam CS, Wang C, Hu Q, Dheen ST. Subhramanyam CS, et al. Semin Cell Dev Biol. 2019 Oct;94:112-120. doi: 10.1016/j.semcdb.2019.05.004. Epub 2019 May 11. Semin Cell Dev Biol. 2019. PMID: 31077796 Review.
However, when there is a neuronal injury or other insult, depending on the type and magnitude of stimuli, microglia will be activated to secrete either proinflammatory factors that enhance cytotoxicity or anti-inflammatory neuroprotective factors that assist in wound heali …
However, when there is a neuronal injury or other insult, depending on the type and magnitude of stimuli, microglia will be activated …
Molecular mechanisms of ferroptosis and their involvement in brain diseases.
Costa I, Barbosa DJ, Benfeito S, Silva V, Chavarria D, Borges F, Remião F, Silva R. Costa I, et al. Pharmacol Ther. 2023 Apr;244:108373. doi: 10.1016/j.pharmthera.2023.108373. Epub 2023 Mar 8. Pharmacol Ther. 2023. PMID: 36894028 Free article. Review.
RSL3, statins, Ml162 and Ml210 induce ferroptosis by inhibiting glutathione peroxidase 4 (GPX4), which is responsible for preventing the formation of lipid peroxides, and FIN56 and withaferin trigger GPX4 degradation. ...Increased evidence has established the involvement o …
RSL3, statins, Ml162 and Ml210 induce ferroptosis by inhibiting glutathione peroxidase 4 (GPX4), which is responsible for preventing …
Symptomatic treatments for amyotrophic lateral sclerosis/motor neuron disease.
Ng L, Khan F, Young CA, Galea M. Ng L, et al. Cochrane Database Syst Rev. 2017 Jan 10;1(1):CD011776. doi: 10.1002/14651858.CD011776.pub2. Cochrane Database Syst Rev. 2017. PMID: 28072907 Free PMC article. Review.
BACKGROUND: Motor neuron disease (MND), which is also known as amyotrophic lateral sclerosis (ALS), causes a wide range of symptoms but the evidence base for the effectiveness of the symptomatic treatment therapies is limited. ...Treatment for sialorrhoeaA si …
BACKGROUND: Motor neuron disease (MND), which is also known as amyotrophic lateral sclerosis (ALS), causes a wide range …
Treatment for sialorrhea (excessive saliva) in people with motor neuron disease/amyotrophic lateral sclerosis.
James E, Ellis C, Brassington R, Sathasivam S, Young CA. James E, et al. Cochrane Database Syst Rev. 2022 May 20;5(5):CD006981. doi: 10.1002/14651858.CD006981.pub3. Cochrane Database Syst Rev. 2022. PMID: 35593746 Free PMC article. Review.
BACKGROUND: Motor neuron disease (MND), also known as amyotrophic lateral sclerosis (ALS), is a progressive neurodegenerative condition that may cause dysphagia, as well as limb weakness, dysarthria, emotional lability, and respiratory failure. ...The trial p …
BACKGROUND: Motor neuron disease (MND), also known as amyotrophic lateral sclerosis (ALS), is a progressive neurodegene …
Impaired autophagy and APP processing in Alzheimer's disease: The potential role of Beclin 1 interactome.
Salminen A, Kaarniranta K, Kauppinen A, Ojala J, Haapasalo A, Soininen H, Hiltunen M. Salminen A, et al. Prog Neurobiol. 2013 Jul-Aug;106-107:33-54. doi: 10.1016/j.pneurobio.2013.06.002. Epub 2013 Jul 1. Prog Neurobiol. 2013. PMID: 23827971 Review.
The accumulation of amyloid-beta-containing neuritic plaques and intracellular tau protein tangles are key histopathological hallmarks of Alzheimer's disease (AD). This type of pathology clearly indicates that the mechanisms of neuronal housekeeping and protein quality con …
The accumulation of amyloid-beta-containing neuritic plaques and intracellular tau protein tangles are key histopathological hallmarks of Al …
N-acetylcysteine (NAC) in neurological disorders: mechanisms of action and therapeutic opportunities.
Bavarsad Shahripour R, Harrigan MR, Alexandrov AV. Bavarsad Shahripour R, et al. Brain Behav. 2014 Mar;4(2):108-22. doi: 10.1002/brb3.208. Epub 2014 Jan 13. Brain Behav. 2014. PMID: 24683506 Free PMC article. Review.
Herein, we discuss NAC molecular, intracellular, and systemic effects, focusing on its potential applications in neurodegenerative diseases including spinocerebellar ataxia, Parkinson's disease, tardive dyskinesia, myoclonus epilepsy of the Unverricht-Lundbor type as well …
Herein, we discuss NAC molecular, intracellular, and systemic effects, focusing on its potential applications in neurodegenerative diseases …
Rate of familial amyotrophic lateral sclerosis: a systematic review and meta-analysis.
Byrne S, Walsh C, Lynch C, Bede P, Elamin M, Kenna K, McLaughlin R, Hardiman O. Byrne S, et al. J Neurol Neurosurg Psychiatry. 2011 Jun;82(6):623-7. doi: 10.1136/jnnp.2010.224501. Epub 2010 Nov 3. J Neurol Neurosurg Psychiatry. 2011. PMID: 21047878 Review.
BACKGROUND: The population rate of familial amyotrophic lateral sclerosis (FALS) is frequently reported as 10%. ...Thirty-three papers were included in analysis and the rate of FALS for all studies was 4.6% (95% CI 3.9% to 5.5%). Restricting the analys …
BACKGROUND: The population rate of familial amyotrophic lateral sclerosis (FALS) is frequently reported as 10%. ...Thir …
Palliative care in amyotrophic lateral sclerosis: a review of current international guidelines and initiatives.
Bede P, Oliver D, Stodart J, van den Berg L, Simmons Z, O Brannagáin D, Borasio GD, Hardiman O. Bede P, et al. J Neurol Neurosurg Psychiatry. 2011 Apr;82(4):413-8. doi: 10.1136/jnnp.2010.232637. Epub 2011 Feb 5. J Neurol Neurosurg Psychiatry. 2011. PMID: 21297150 Review.
BACKGROUND: Amyotrophic lateral sclerosis (ALS) is a relentlessly progressive neurodegenerative condition. Optimal management requires a palliative approach from diagnosis with emphasis on patient autonomy, dignity and quality of life. OBJECTIVE: To conduct a …
BACKGROUND: Amyotrophic lateral sclerosis (ALS) is a relentlessly progressive neurodegenerative condition. Optimal mana …
Molecular and pharmacological chaperones for SOD1.
Wright GSA. Wright GSA. Biochem Soc Trans. 2020 Aug 28;48(4):1795-1806. doi: 10.1042/BST20200318. Biochem Soc Trans. 2020. PMID: 32794552 Free PMC article. Review.
Mutations can prevent SOD1 post-translational processing leading to misfolding and cytoplasmic aggregation in familial amyotrophic lateral sclerosis (ALS). Evidence of immature, wild-type SOD1 misfolding has also been observed in sporadic ALS, non-SOD1 …
Mutations can prevent SOD1 post-translational processing leading to misfolding and cytoplasmic aggregation in familial amyotrophic
Decoding the relationship between ageing and amyotrophic lateral sclerosis: a cellular perspective.
Pandya VA, Patani R. Pandya VA, et al. Brain. 2020 Apr 1;143(4):1057-1072. doi: 10.1093/brain/awz360. Brain. 2020. PMID: 31851317 Free PMC article. Review.
With an ageing population comes an inevitable increase in the prevalence of age-associated neurodegenerative diseases, such as amyotrophic lateral sclerosis (ALS), a relentlessly progressive and universally fatal disease characterized by the degeneration of u …
With an ageing population comes an inevitable increase in the prevalence of age-associated neurodegenerative diseases, such as amyotrophi
103 results