Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Edit custom filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1951 1
1952 1
1955 1
1956 2
1958 1
1960 1
1961 1
1965 5
1966 3
1967 2
1968 4
1969 6
1970 5
1971 13
1972 10
1973 8
1974 9
1975 16
1976 14
1977 19
1978 13
1979 17
1980 13
1981 22
1982 23
1983 38
1984 34
1985 68
1986 49
1987 41
1988 64
1989 84
1990 67
1991 82
1992 79
1993 91
1994 93
1995 93
1996 111
1997 133
1998 128
1999 127
2000 165
2001 183
2002 245
2003 274
2004 282
2005 249
2006 317
2007 367
2008 362
2009 360
2010 375
2011 447
2012 425
2013 522
2014 539
2015 551
2016 574
2017 548
2018 637
2019 679
2020 741
2021 724
2022 695
2023 601
2024 755
2025 920
2026 501

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

13,069 results

Results by year

Filters applied: . Clear all
Page 1
Targeting ferroptosis as a prospective therapeutic approach for diabetic nephropathy.
Wu Q, Huang F. Wu Q, et al. Ann Med. 2024 Dec;56(1):2346543. doi: 10.1080/07853890.2024.2346543. Epub 2024 Apr 24. Ann Med. 2024. PMID: 38657163 Free PMC article. Review.
However, there are limited drugs targeting the treatment of DN. Owing to this, it is highly crucial to investigate the pathogenesis and potential therapeutic targets of DN. ...A primary mechanism of ferroptosis is associated with iron metabolism, lipid met …
However, there are limited drugs targeting the treatment of DN. Owing to this, it is highly crucial to investigate the pathogenesis a …
NAC alleviative ferroptosis in diabetic nephropathy via maintaining mitochondrial redox homeostasis through activating SIRT3-SOD2/Gpx4 pathway.
Li Q, Liao J, Chen W, Zhang K, Li H, Ma F, Zhang H, Han Q, Guo J, Li Y, Hu L, Pan J, Tang Z. Li Q, et al. Free Radic Biol Med. 2022 Jul;187:158-170. doi: 10.1016/j.freeradbiomed.2022.05.024. Epub 2022 May 31. Free Radic Biol Med. 2022. PMID: 35660452
Diabetic nephropathy (DN) is known as a major microvascular complication in type 1 diabetes. The effect of insulin treatment alone on controlling blood glucose is unsatisfactory. ...However, whether NAC combined with insulin treatment can further enhance the therapeutic ef …
Diabetic nephropathy (DN) is known as a major microvascular complication in type 1 diabetes. The effect of insulin treatment alone on …
Altered translation elongation contributes to key hallmarks of aging in the killifish brain.
Di Fraia D, Marino A, Lee JH, Kelmer Sacramento E, Baumgart M, Bagnoli S, Balla T, Schalk F, Kamrad S, Guan R, Caterino C, Giannuzzi C, Tomaz da Silva P, Sahu AK, Gut H, Siano G, Tiessen M, Terzibasi-Tozzini E, Fornasiero EF, Gagneur J, Englert C, Patil KR, Correia-Melo C, Nedialkova DD, Frydman J, Cellerino A, Ori A. Di Fraia D, et al. Science. 2025 Jul 31;389(6759):eadk3079. doi: 10.1126/science.adk3079. Epub 2025 Jul 31. Science. 2025. PMID: 40743332 Free PMC article.
This vulnerability may represent a unifying principle that connects various aging hallmarks, encompassing genome integrity, proteostasis, and the biosynthesis of macromolecules....
This vulnerability may represent a unifying principle that connects various aging hallmarks, encompassing genome integrity, proteostasis, an …
Rewiring of cortical glucose metabolism fuels human brain cancer growth.
Scott AJ, Mittal A, Meghdadi B, O'Brien A, Bailleul J, Sravya P, Achreja A, Zhou W, Xu J, Lin A, Wilder-Romans K, Liang N, Kothari AU, Korimerla N, Edwards DM, Wu Z, Feng J, Su S, Zhang L, Sajjakulnukit P, Andren AC, Park JO, Ten Hoeve J, Tarnal V, Redic KA, Qi NR, Fischer JL, Yang E, Regan MS, Stopka SA, Baquer G, Suresh K, Sarkaria JN, Lawrence TS, Venneti S, Agar NYR, Vlashi E, Lyssiotis CA, Al-Holou WN, Nagrath D, Wahl DR. Scott AJ, et al. Nature. 2025 Oct;646(8084):413-422. doi: 10.1038/s41586-025-09460-7. Epub 2025 Sep 3. Nature. 2025. PMID: 40903569 Free PMC article.
Targeting this metabolic rewiring in mice through dietary amino acid modulation selectively alters glioblastoma metabolism, slows tumour growth and augments the efficacy of standard-of-care treatments. ...
Targeting this metabolic rewiring in mice through dietary amino acid modulation selectively alters glioblastoma metabolism, slows tum …
PI3Kβ functions as a protein kinase to promote cellular protein O-GlcNAcylation and acetyl-CoA production for tumor growth.
He X, Chen D, Liu G, Wu Q, Zhao H, Guo D, Jiang X, Li M, Meng Y, Yin Y, Ye X, Luo S, Xia Y, Hunter T, Lu Z. He X, et al. Mol Cell. 2025 Apr 3;85(7):1411-1425.e8. doi: 10.1016/j.molcel.2025.02.024. Epub 2025 Mar 24. Mol Cell. 2025. PMID: 40132583
These findings underscore the critical role of PI3Kbeta in governing protein O-GlcNAcylation, fatty acid metabolism, and chromatin modification through its protein kinase activity and provide instrumental insight into the roles of PI3K in tumor progression....
These findings underscore the critical role of PI3Kbeta in governing protein O-GlcNAcylation, fatty acid metabolism, and chromatin mo …
PEX11B palmitoylation couples peroxisomal dysfunction with Schwann cells fail in diabetic neuropathy.
Yang YM, Ma HB, Xiong Y, Wu Q, Gao XK. Yang YM, et al. J Biomed Sci. 2025 Feb 12;32(1):20. doi: 10.1186/s12929-024-01115-5. J Biomed Sci. 2025. PMID: 39934809 Free PMC article.
Lastly, MR analysis indicates a notable causal influence of DN on MS, with its onset and progression intricately linked to peroxisomal dysfunction. CONCLUSIONS: Targeting the peroxisomal biogenesis pathway may be an effective strategy for preventing and treating DN, …
Lastly, MR analysis indicates a notable causal influence of DN on MS, with its onset and progression intricately linked to peroxisoma …
Trained Immunity and Reactivity of Macrophages and Endothelial Cells.
Drummer C 4th, Saaoud F, Shao (邵颖) Y, Sun (孙宇) Y, Xu (徐克曼) K, Lu (路一凡) Y, Ni (倪栋) D, Atar D, Jiang (蒋晓华) X, Wang (王虹) H, Yang X. Drummer C 4th, et al. Arterioscler Thromb Vasc Biol. 2021 Mar;41(3):1032-1046. doi: 10.1161/ATVBAHA.120.315452. Epub 2020 Dec 31. Arterioscler Thromb Vasc Biol. 2021. PMID: 33380171 Free PMC article. Review.
Furthermore, TI in ECs is functional for inflammation effectiveness and transition to chronic inflammation. Rewiring of cellular metabolism of the trained cells takes place during induction of TI, including increased glycolysis, glutaminolysis, increased accumulation of tr …
Furthermore, TI in ECs is functional for inflammation effectiveness and transition to chronic inflammation. Rewiring of cellular metaboli …
Epigenetic Regulations in Diabetic Nephropathy.
Lu Z, Liu N, Wang F. Lu Z, et al. J Diabetes Res. 2017;2017:7805058. doi: 10.1155/2017/7805058. Epub 2017 Mar 19. J Diabetes Res. 2017. PMID: 28401169 Free PMC article. Review.
Diabetic nephropathy (DN) is a chronic complication of diabetes and the most common cause of end-stage kidney disease. ...All these findings can contribute to developing novel therapies for DN....
Diabetic nephropathy (DN) is a chronic complication of diabetes and the most common cause of end-stage kidney disease. ...All these f …
Role of sex hormones in diabetic nephropathy.
Liu J, Liu Z, Sun W, Luo L, An X, Yu D, Wang W. Liu J, et al. Front Endocrinol (Lausanne). 2023 Apr 18;14:1135530. doi: 10.3389/fendo.2023.1135530. eCollection 2023. Front Endocrinol (Lausanne). 2023. PMID: 37143724 Free PMC article. Review.
A growing number of epidemiological and clinical studies suggest that sex hormones play an important role in the onset and progression of DN. Testosterone is the main sex hormone in males and is thought to accelerate the occurrence and progression of DN. ...H …
A growing number of epidemiological and clinical studies suggest that sex hormones play an important role in the onset and progression of …
[Pathogenic Mechanisms of Diabetic Neuropathy].
Sango K, Yako H, Takaku S, Niimi N. Sango K, et al. Brain Nerve. 2024 May;76(5):671-680. doi: 10.11477/mf.1416202658. Brain Nerve. 2024. PMID: 38741511 Review. Japanese.
Diabetes stands as the predominant cause of peripheral neuropathy, and diabetic neuropathy (DN) is an early-onset and most frequent complication of diabetes. Distal symmetric polyneuropathy is the major form of DN; however, various patterns of nerve injury can manif …
Diabetes stands as the predominant cause of peripheral neuropathy, and diabetic neuropathy (DN) is an early-onset and most frequent c …
13,069 results
You have reached the last available page of results. Please see the User Guide for more information.