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Analysis of cluster randomised stepped wedge trials with repeated cross-sectional samples.
Hemming K, Taljaard M, Forbes A. Hemming K, et al. Trials. 2017 Mar 4;18(1):101. doi: 10.1186/s13063-017-1833-7. Trials. 2017. PMID: 28259174 Free PMC article.
BACKGROUND: The stepped wedge cluster randomised trial (SW-CRT) is increasingly being used to evaluate policy or service delivery interventions. However, there is a dearth of trials literature addressing analytical approaches to the SW-CR …
BACKGROUND: The stepped wedge cluster randomised trial (SW-CRT) is increasingly being used to evaluate po …
Power analysis for stepped wedge trials with multiple interventions.
Sundin P, Crespi CM. Sundin P, et al. Stat Med. 2022 Apr 15;41(8):1498-1512. doi: 10.1002/sim.9301. Epub 2022 Jan 11. Stat Med. 2022. PMID: 35014710
Stepped wedge design (SWD) trials are cluster randomized trials that feature staggered, unidirectional cross-over between treatment conditions. ...We derive standard errors of the intervention effect coefficients, and present power calcul …
Stepped wedge design (SWD) trials are cluster randomized trials that feature staggered, unidirecti …
Impact of unequal cluster sizes for GEE analyses of stepped wedge cluster randomized trials with binary outcomes.
Tian Z, Preisser JS, Esserman D, Turner EL, Rathouz PJ, Li F. Tian Z, et al. Biom J. 2022 Mar;64(3):419-439. doi: 10.1002/bimj.202100112. Epub 2021 Oct 1. Biom J. 2022. PMID: 34596912 Free PMC article.
The stepped wedge (SW) design is a type of unidirectional crossover design where cluster units switch from control to intervention condition at different prespecified time points. While a convention in study planning is to assume the cluster-period siz …
The stepped wedge (SW) design is a type of unidirectional crossover design where cluster units switch from control to i …
Systematic review finds major deficiencies in sample size methodology and reporting for stepped-wedge cluster randomised trials.
Martin J, Taljaard M, Girling A, Hemming K. Martin J, et al. BMJ Open. 2016 Feb 4;6(2):e010166. doi: 10.1136/bmjopen-2015-010166. BMJ Open. 2016. PMID: 26846897 Free PMC article. Review.
BACKGROUND: Stepped-wedge cluster randomised trials (SW-CRT) are increasingly being used in health policy and services research, but unless they are conducted and reported to the highest methodological standards, they are unlikely to be useful t …
BACKGROUND: Stepped-wedge cluster randomised trials (SW-CRT) are increasingly being used in health policy …
Sample size determination for stepped wedge cluster randomized trials in pragmatic settings.
Wang J, Cao J, Zhang S, Ahn C. Wang J, et al. Stat Methods Med Res. 2021 Jul;30(7):1609-1623. doi: 10.1177/09622802211022392. Epub 2021 Jun 17. Stat Methods Med Res. 2021. PMID: 34139916
The stepped-wedge cluster randomized design has been increasingly employed by pragmatic trials in health services research. In this study, based on the GEE approach, we present closed-form sample size calculation that is applicable to bot …
The stepped-wedge cluster randomized design has been increasingly employed by pragmatic trials in health …
Adherence to key recommendations for design and analysis of stepped-wedge cluster randomized trials: A review of trials published 2016-2022.
Nevins P, Ryan M, Davis-Plourde K, Ouyang Y, Pereira Macedo JA, Meng C, Tong G, Wang X, Ortiz-Reyes L, Caille A, Li F, Taljaard M. Nevins P, et al. Clin Trials. 2024 Apr;21(2):199-210. doi: 10.1177/17407745231208397. Epub 2023 Nov 21. Clin Trials. 2024. PMID: 37990575 Free PMC article. Review.
BACKGROUND/AIMS: The stepped-wedge cluster randomized trial (SW-CRT), in which clusters are randomized to a time at which they will transition to the intervention condition - rather than a trial arm - is a relatively new des …
BACKGROUND/AIMS: The stepped-wedge cluster randomized trial (SW-CRT), in which clusters are ran …
Efficacy and cost-effectiveness of a community-based model of care for older patients with complex needs: a study protocol for a multicentre randomised controlled trial using a stepped wedge cluster design.
Kinchin I, Jacups S, Mann J, Quigley R, Harvey D, Doran CM, Strivens E. Kinchin I, et al. Trials. 2018 Dec 4;19(1):668. doi: 10.1186/s13063-018-3038-0. Trials. 2018. PMID: 30514378 Free PMC article.
An economic evaluation will determine whether OPEN ARCH is cost-effective when compared to the standard care. METHODS/DESIGN: This multicentre randomised controlled trial uses a stepped wedge cluster design with repeated cross-s …
An economic evaluation will determine whether OPEN ARCH is cost-effective when compared to the standard care. METHODS/DESIGN: This multicent …
Optimal designs using generalized estimating equations in cluster randomized crossover and stepped wedge trials.
Liu J, Li F. Liu J, et al. Stat Methods Med Res. 2024 Aug;33(8):1299-1330. doi: 10.1177/09622802241247717. Epub 2024 May 30. Stat Methods Med Res. 2024. PMID: 38813761
Cluster randomized crossover and stepped wedge cluster randomized trials are two types of longitudinal cluster randomized trials that leverage both the within- and between-cluster comparisons to estimate …
Cluster randomized crossover and stepped wedge cluster randomized trials are two types of l …
Proceedings of the First International Conference on Stepped Wedge Trial Design : York, UK, 10 March 2016.
Kanaan M, Mdege ND, Keding A, Parker RA, Mills N, Shah A, Strachan F, Keerie C, Weir CJ, Forbes A, Hemming K, Lawton SA, Healey E, Lewis M, Nicholls E, Jinks C, Tan V, Finney A, Mallen CD; on behalf of the ENHANCE Study Team; Lenguerrand E, MacLennan G, Norrie J, Bhattacharya S, Draycott T; on behalf of the Thistle group; Hooper R, Teerenstra S, de Hoop E, Eldridge S, Girling A, Taljaard M, Di Tanna GL, Gasparrini A, Casula A, Caskey F, Lenguerrand E, Methven S, MacNeill S, May M, Selby N, Danon L, Christensen H, Finn A, May M, Takanashi F, Keding A, Crouch S, Kanaan M, Kristunas CA, Smith KL, Gray LJ, Matthews JNS, Salman RAS, Parker RA, Maxwell A, Dennis M, Rudd A, Weir CJ, Thompson JA, Fielding KL, Davey C, Aiken AM, Hargreaves JR, Hayes RJ, Lyons VH, Li L, Hughes J, Rowhani-Rahbar A, Hemming K, Taljaard M, Forbes A. Kanaan M, et al. Trials. 2016 Jul 18;17 Suppl 1(Suppl 1):311. doi: 10.1186/s13063-016-1436-8. Trials. 2016. PMID: 27454562 Free PMC article.
I1 Introduction Mona Kanaan, Noreen Dadirai Mdege, Ada Keding O1 The HiSTORIC trial: a hybrid before-and-after and stepped wedge design RA Parker, N Mills, A Shah, F Strachan, C Keerie, CJ Weir O2 Stepped wedge trials with non-uniform cor …
I1 Introduction Mona Kanaan, Noreen Dadirai Mdege, Ada Keding O1 The HiSTORIC trial: a hybrid before-and-after and stepped …
Impact of non-uniform correlation structure on sample size and power in multiple-period cluster randomised trials.
Kasza J, Hemming K, Hooper R, Matthews J, Forbes AB. Kasza J, et al. Stat Methods Med Res. 2019 Mar;28(3):703-716. doi: 10.1177/0962280217734981. Epub 2017 Oct 13. Stat Methods Med Res. 2019. PMID: 29027505
Stepped wedge and cluster randomised crossover trials are examples of cluster randomised designs conducted over multiple time periods that are being used with increasing frequency in health research. ...Motivated by a proposed inte …
Stepped wedge and cluster randomised crossover trials are examples of cluster randomised de …