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Bone turnover markers are differentially affected by pre-analytical handling.
Christensen GL, Halgreen JR, Milenkovski M, Köse A, Quardon N, Jørgensen NR. Christensen GL, et al. Osteoporos Int. 2019 May;30(5):1137-1141. doi: 10.1007/s00198-019-04837-7. Epub 2019 Jan 24. Osteoporos Int. 2019. PMID: 30680430
We have evaluated how sample type, time before separation of blood samples, and time between separation and analysis affect the stability of four bone turnover markers. ...The aim of the current study was to evaluate how time before separation o …
We have evaluated how sample type, time before separation of blood samples, and time between separation and analysis affect th …
Thalassemic osteopathy: a new marker of bone deposition.
Baldini M, Forti S, Orsatti A, Marcon A, Ulivieri FM, Airaghi L, Zanaboni L, Cappellini MD. Baldini M, et al. Blood Cells Mol Dis. 2014 Feb-Mar;52(2-3):91-4. doi: 10.1016/j.bcmd.2013.09.008. Epub 2013 Oct 3. Blood Cells Mol Dis. 2014. PMID: 24091145
The amino-terminal pro-peptide of type I procollagen (P1NP) is a recently introduced marker that is considered the most sensitive index of bone formation. ...P1NP and CTX assays show good precision and low analytical CV, and, compared to …
The amino-terminal pro-peptide of type I procollagen (P1NP) is a recently introduced marker that is considered the most sensit …
Algorithm for the Use of Biochemical Markers of Bone Turnover in the Diagnosis, Assessment and Follow-Up of Treatment for Osteoporosis.
Lorentzon M, Branco J, Brandi ML, Bruyère O, Chapurlat R, Cooper C, Cortet B, Diez-Perez A, Ferrari S, Gasparik A, Herrmann M, Jorgensen NR, Kanis J, Kaufman JM, Laslop A, Locquet M, Matijevic R, McCloskey E, Minisola S, Pikner R, Reginster JY, Rizzoli R, Szulc P, Vlaskovska M, Cavalier E. Lorentzon M, et al. Adv Ther. 2019 Oct;36(10):2811-2824. doi: 10.1007/s12325-019-01063-9. Epub 2019 Aug 22. Adv Ther. 2019. PMID: 31440982 Free PMC article.
INTRODUCTION: Increased biochemical bone turnover markers (BTMs) measured in serum are associated with bone loss, increased fracture risk and poor treatment adherence, but their role in clinical practice is presently unclear. ...METHODS: A working grou …
INTRODUCTION: Increased biochemical bone turnover markers (BTMs) measured in serum are associated with bone loss …
Evaluation of different bone markers in hemodialyzed patients.
Cavalier E, Delanaye P, Collette J, Krzesinski JM, Chapelle JP. Cavalier E, et al. Clin Chim Acta. 2006 Sep;371(1-2):107-11. doi: 10.1016/j.cca.2006.02.029. Epub 2006 Mar 2. Clin Chim Acta. 2006. PMID: 16600202 Free article.
This ratio was significantly (p<0.05) higher in low and high bone turnover patients than in normal patients according to the K/DOQI. We found a correlation between low levels of 25VTD and high levels of HCY. CONCLUSIONS: BALP offers the best clinical and analy
This ratio was significantly (p<0.05) higher in low and high bone turnover patients than in normal patients according to th …
Greater change in bone turnover markers for efavirenz/emtricitabine/tenofovir disoproxil fumarate versus dolutegravir + abacavir/lamivudine in antiretroviral therapy-naive adults over 144 weeks.
Tebas P, Kumar P, Hicks C, Granier C, Wynne B, Min S, Pappa K. Tebas P, et al. AIDS. 2015 Nov 28;29(18):2459-64. doi: 10.1097/QAD.0000000000000863. AIDS. 2015. PMID: 26355674 Free PMC article. Clinical Trial.
OBJECTIVE: Antiretroviral therapy initiation has been linked to bone mineral density and bone biomarker changes. We assessed long-term bone turnover biomarker effects over 144 weeks in patients initiating dolutegravir (DTG) + abacavir/lamivudine (ABC/3 …
OBJECTIVE: Antiretroviral therapy initiation has been linked to bone mineral density and bone biomarker changes. We assessed l …