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New Hybrid Compounds Combining Fragments of Usnic Acid and Thioether Are Inhibitors of Human Enzymes TDP1, TDP2 and PARP1.
Dyrkheeva NS, Filimonov AS, Luzina OA, Orlova KA, Chernyshova IA, Kornienko TE, Malakhova AA, Medvedev SP, Zakharenko AL, Ilina ES, Anarbaev RO, Naumenko KN, Klabenkova KV, Burakova EA, Stetsenko DA, Zakian SM, Salakhutdinov NF, Lavrik OI. Dyrkheeva NS, et al. Among authors: anarbaev ro. Int J Mol Sci. 2021 Oct 20;22(21):11336. doi: 10.3390/ijms222111336. Int J Mol Sci. 2021. PMID: 34768766 Free PMC article.
Deoxycholic acid as a molecular scaffold for tyrosyl-DNA phosphodiesterase 1 inhibition: A synthesis, structure-activity relationship and molecular modeling study.
Salomatina OV, Popadyuk II, Zakharenko AL, Zakharova OD, Chepanova AA, Dyrkheeva NS, Komarova NI, Reynisson J, Anarbaev RO, Salakhutdinov NF, Lavrik OI, Volcho KP. Salomatina OV, et al. Among authors: anarbaev ro. Steroids. 2021 Jan;165:108771. doi: 10.1016/j.steroids.2020.108771. Epub 2020 Nov 19. Steroids. 2021. PMID: 33221302
The First Berberine-Based Inhibitors of Tyrosyl-DNA Phosphodiesterase 1 (Tdp1), an Important DNA Repair Enzyme.
Gladkova ED, Nechepurenko IV, Bredikhin RA, Chepanova AA, Zakharenko AL, Luzina OA, Ilina ES, Dyrkheeva NS, Mamontova EM, Anarbaev RO, Reynisson J, Volcho KP, Salakhutdinov NF, Lavrik OI. Gladkova ED, et al. Among authors: anarbaev ro. Int J Mol Sci. 2020 Sep 28;21(19):7162. doi: 10.3390/ijms21197162. Int J Mol Sci. 2020. PMID: 32998385 Free PMC article.
25 results