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Ancillary subunits associated with voltage-dependent K+ channels.
Pongs O, Schwarz JR. Pongs O, et al. Physiol Rev. 2010 Apr;90(2):755-96. doi: 10.1152/physrev.00020.2009. Physiol Rev. 2010. PMID: 20393197 Free article. Review.
The ancillary subunits are often integral parts of native Kv channels, which, therefore, are mostly multiprotein complexes composed of voltage-sensing and pore-forming Kvalpha-subunits and of ancillary or beta-subunits. ...Ancil …
The ancillary subunits are often integral parts of native Kv channels, which, therefore, are mostly multiprotein comple …
KCNE4-dependent functional consequences of Kv1.3-related leukocyte physiology.
Vallejo-Gracia A, Sastre D, Colomer-Molera M, Solé L, Navarro-Pérez M, Capera J, Roig SR, Pedrós-Gámez O, Estadella I, Szilágyi O, Panyi G, Hajdú P, Felipe A. Vallejo-Gracia A, et al. Sci Rep. 2021 Jul 16;11(1):14632. doi: 10.1038/s41598-021-94015-9. Sci Rep. 2021. PMID: 34272451 Free PMC article.
The voltage-dependent potassium channel Kv1.3 plays essential roles in the immune system, participating in leukocyte activation, proliferation and apoptosis. The regulatory subunit KCNE4 acts as an ancillary peptide of Kv1.3, modulates K( …
The voltage-dependent potassium channel Kv1.3 plays essential roles in the immune system, participating in leukocyte ac …
KCNE gene expression is dependent on the proliferation and mode of activation of leukocytes.
Solé L, Vallejo-Gracia A, Roig SR, Serrano-Albarrás A, Marruecos L, Manils J, Gómez D, Soler C, Felipe A. Solé L, et al. Channels (Austin). 2013 Mar-Apr;7(2):85-96. doi: 10.4161/chan.23258. Epub 2013 Jan 17. Channels (Austin). 2013. PMID: 23327879 Free PMC article.
Voltage-dependent K (+) (Kv) channels are tightly regulated during the immune system response. ...A functional Kv channel is an oligomeric complex composed of pore-forming and ancillary subunits. ...
Voltage-dependent K (+) (Kv) channels are tightly regulated during the immune system response. ...A functional K …
Impaired Kv7 channel function in cerebral arteries of a tauopathy mouse model (rTg4510).
de Jong IEM, Jepps TA. de Jong IEM, et al. Physiol Rep. 2018 Dec;6(23):e13920. doi: 10.14814/phy2.13920. Physiol Rep. 2018. PMID: 30548427 Free PMC article.
The precise mechanisms that underlie this vascular dysfunction remain unclear. Kv7 voltage-dependent K(+) channels contribute to the development of myogenic tone in rat cerebral arteries. ...The quantitative PCR analysis of the cerebral arteries found …
The precise mechanisms that underlie this vascular dysfunction remain unclear. Kv7 voltage-dependent K(+) channels …
Structural determinants of fast inactivation of high voltage-activated Ca(2+) channels.
Stotz SC, Zamponi GW. Stotz SC, et al. Trends Neurosci. 2001 Mar;24(3):176-81. doi: 10.1016/s0166-2236(00)01738-0. Trends Neurosci. 2001. PMID: 11182458 Review.
The fast inactivation of voltage-dependent Ca(2+) channels is a key mechanism that contributes to the precise control of Ca(2+) entry into excitable cells. Recent advances have revealed that multiple structural elements contribute to the intrinsic inactivatio …
The fast inactivation of voltage-dependent Ca(2+) channels is a key mechanism that contributes to the precise control o …
A role for DPPX modulating external TEA sensitivity of Kv4 channels.
Colinas O, Pérez-Carretero FD, López-López JR, Pérez-García MT. Colinas O, et al. J Gen Physiol. 2008 May;131(5):455-71. doi: 10.1085/jgp.200709912. Epub 2008 Apr 14. J Gen Physiol. 2008. PMID: 18411327 Free PMC article.
Shal-type (Kv4) channels are expressed in a large variety of tissues, where they contribute to transient voltage-dependent K+ currents. ...Our data suggest that DPPX proteins are integral components of K(O2) currents, and that their associati …
Shal-type (Kv4) channels are expressed in a large variety of tissues, where they contribute to transient voltage-dependent …
Sexual dimorphism and oestrogen regulation of KCNE3 expression modulates the functional properties of KCNQ1 K⁺ channels.
Alzamora R, O'Mahony F, Bustos V, Rapetti-Mauss R, Urbach V, Cid LP, Sepúlveda FV, Harvey BJ. Alzamora R, et al. J Physiol. 2011 Nov 1;589(Pt 21):5091-107. doi: 10.1113/jphysiol.2011.215772. Epub 2011 Sep 12. J Physiol. 2011. PMID: 21911611 Free PMC article.
The KCNQ1 potassium channel associates with various KCNE ancillary subunits that drastically affect channel gating and pharmacology. ...Whole-cell K(+) currents showed a linear current-voltage relationship in male crypts, while …
The KCNQ1 potassium channel associates with various KCNE ancillary subunits that drastically affect channel …