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In nondiabetic, human immunodeficiency virus-infected patients with lipodystrophy, hepatic insulin extraction and posthepatic insulin clearance rate are decreased in proportion to insulin resistance.
Haugaard SB, Andersen O, Hansen BR, Andersen UB, Vølund A, Iversen J, Nielsen JO, Madsbad S. Haugaard SB, et al. Among authors: andersen o, andersen ub. Metabolism. 2005 Feb;54(2):171-9. doi: 10.1016/j.metabol.2004.08.009. Metabolism. 2005. PMID: 15690310 Clinical Trial.
Insulin secretion in lipodystrophic HIV-infected patients is associated with high levels of nonglucose secretagogues and insulin resistance of beta-cells.
Haugaard SB, Andersen O, Storgaard H, Dela F, Holst JJ, Iversen J, Nielsen JO, Madsbad S. Haugaard SB, et al. Among authors: andersen o. Am J Physiol Endocrinol Metab. 2004 Oct;287(4):E677-85. doi: 10.1152/ajpendo.00009.2004. Epub 2004 May 18. Am J Physiol Endocrinol Metab. 2004. PMID: 15149949 Clinical Trial.
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