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ESAT-6 proteins: protective antigens and virulence factors?
Brodin P, Rosenkrands I, Andersen P, Cole ST, Brosch R. Brodin P, et al. Among authors: andersen p. Trends Microbiol. 2004 Nov;12(11):500-8. doi: 10.1016/j.tim.2004.09.007. Trends Microbiol. 2004. PMID: 15488391 Review.
A multistage tuberculosis vaccine that confers efficient protection before and after exposure.
Aagaard C, Hoang T, Dietrich J, Cardona PJ, Izzo A, Dolganov G, Schoolnik GK, Cassidy JP, Billeskov R, Andersen P. Aagaard C, et al. Among authors: andersen p. Nat Med. 2011 Feb;17(2):189-94. doi: 10.1038/nm.2285. Epub 2011 Jan 23. Nat Med. 2011. PMID: 21258338
Adult-like anti-mycobacterial T cell and in vivo dendritic cell responses following neonatal immunization with Ag85B-ESAT-6 in the IC31 adjuvant.
Kamath AT, Rochat AF, Valenti MP, Agger EM, Lingnau K, Andersen P, Lambert PH, Siegrist CA. Kamath AT, et al. Among authors: andersen p. PLoS One. 2008;3(11):e3683. doi: 10.1371/journal.pone.0003683. Epub 2008 Nov 10. PLoS One. 2008. PMID: 18997860 Free PMC article.
ESAT-6 (EsxA) and TB10.4 (EsxH) based vaccines for pre- and post-exposure tuberculosis vaccination.
Hoang T, Aagaard C, Dietrich J, Cassidy JP, Dolganov G, Schoolnik GK, Lundberg CV, Agger EM, Andersen P. Hoang T, et al. Among authors: andersen p. PLoS One. 2013 Dec 12;8(12):e80579. doi: 10.1371/journal.pone.0080579. eCollection 2013. PLoS One. 2013. PMID: 24349004 Free PMC article.
Introducing the ESAT-6 free IGRA, a companion diagnostic for TB vaccines based on ESAT-6.
Ruhwald M, de Thurah L, Kuchaka D, Zaher MR, Salman AM, Abdel-Ghaffar AR, Shoukry FA, Michelsen SW, Soborg B, Blauenfeldt T, Mpagama S, Hoff ST, Agger EM, Rosenkrands I, Aagard C, Kibiki G, El-Sheikh N, Andersen P. Ruhwald M, et al. Among authors: andersen p. Sci Rep. 2017 Apr 7;7:45969. doi: 10.1038/srep45969. Sci Rep. 2017. PMID: 28387329 Free PMC article.
Immune responses to ESAT-6 and CFP-10 by FASCIA and multiplex technology for diagnosis of M. tuberculosis infection; IP-10 is a promising marker.
Borgström E, Andersen P, Atterfelt F, Julander I, Källenius G, Maeurer M, Rosenkrands I, Widfeldt M, Bruchfeld J, Gaines H. Borgström E, et al. Among authors: andersen p. PLoS One. 2012;7(11):e43438. doi: 10.1371/journal.pone.0043438. Epub 2012 Nov 8. PLoS One. 2012. PMID: 23144772 Free PMC article.
Cytokine levels for IFN-γ, IP-10, MIP-1β, IL-2, TNF-α, IL-6, IL-10, IL-13 and GM-CSF were significantly higher after stimulation with the Mtb specific antigens ESAT-6 and CFP-10 in patients with active TB compared to healthy controls (p<0.05) and correlated with prolife …
Cytokine levels for IFN-γ, IP-10, MIP-1β, IL-2, TNF-α, IL-6, IL-10, IL-13 and GM-CSF were significantly higher after stimulation with the Mt …
ESAT-6 and CFP-10 in clinical versus environmental isolates of Mycobacterium kansasii.
Arend SM, de Haas P, Leyten E, Rosenkrands I, Rigouts L, Andersen P, Mijs W, van Dissel JT, van Soolingen D. Arend SM, et al. Among authors: andersen p. J Infect Dis. 2005 Apr 15;191(8):1301-10. doi: 10.1086/428950. Epub 2005 Mar 15. J Infect Dis. 2005. PMID: 15776377
CFP10 discriminates between nonacetylated and acetylated ESAT-6 of Mycobacterium tuberculosis by differential interaction.
Okkels LM, Müller EC, Schmid M, Rosenkrands I, Kaufmann SH, Andersen P, Jungblut PR. Okkels LM, et al. Among authors: andersen p. Proteomics. 2004 Oct;4(10):2954-60. doi: 10.1002/pmic.200400906. Proteomics. 2004. PMID: 15378760
Signal regulatory protein alpha (SIRPalpha) cells in the adaptive response to ESAT-6/CFP-10 protein of tuberculous mycobacteria.
Waters WR, Palmer MV, Nonnecke BJ, Thacker TC, Estes DM, Larsen MH, Jacobs WR Jr, Andersen P, McNair J, Minion FC, Lyashchenko KP, Hewinson RG, Vordermeier HM, Sacco RE. Waters WR, et al. Among authors: andersen p. PLoS One. 2009 Jul 29;4(7):e6414. doi: 10.1371/journal.pone.0006414. PLoS One. 2009. PMID: 19641628 Free PMC article.
Use of enzyme-linked immunospot assay with Mycobacterium tuberculosis-specific peptides for diagnosis of recent infection with M. tuberculosis after accidental laboratory exposure.
Leyten EM, Mulder B, Prins C, Weldingh K, Andersen P, Ottenhoff TH, van Dissel JT, Arend SM. Leyten EM, et al. Among authors: andersen p. J Clin Microbiol. 2006 Mar;44(3):1197-201. doi: 10.1128/JCM.44.3.1197-1201.2006. J Clin Microbiol. 2006. PMID: 16517931 Free PMC article.
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