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Single-nucleotide polymorphism rs7754840 of CDKAL1 is associated with impaired insulin secretion in nondiabetic offspring of type 2 diabetic subjects and in a large sample of men with normal glucose tolerance.
Stancáková A, Pihlajamäki J, Kuusisto J, Stefan N, Fritsche A, Häring H, Andreozzi F, Succurro E, Sesti G, Boesgaard TW, Hansen T, Pedersen O, Jansson PA, Hammarstedt A, Smith U, Laakso M; EUGENE2 Consortium. Stancáková A, et al. Among authors: andreozzi f. J Clin Endocrinol Metab. 2008 May;93(5):1924-30. doi: 10.1210/jc.2007-2218. Epub 2008 Feb 19. J Clin Endocrinol Metab. 2008. PMID: 18285412
Activation of the hexosamine pathway leads to phosphorylation of insulin receptor substrate-1 on Ser307 and Ser612 and impairs the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin insulin biosynthetic pathway in RIN pancreatic beta-cells.
Andreozzi F, D'Alessandris C, Federici M, Laratta E, Del Guerra S, Del Prato S, Marchetti P, Lauro R, Perticone F, Sesti G. Andreozzi F, et al. Endocrinology. 2004 Jun;145(6):2845-57. doi: 10.1210/en.2003-0939. Epub 2004 Mar 4. Endocrinology. 2004. PMID: 15001544
Impact of common polymorphisms in candidate genes for insulin resistance and obesity on weight loss of morbidly obese subjects after laparoscopic adjustable gastric banding and hypocaloric diet.
Sesti G, Perego L, Cardellini M, Andreozzi F, Ricasoli C, Vedani P, Guzzi V, Marchi M, Paganelli M, Ferla G, Pontiroli AE, Hribal ML, Folli F. Sesti G, et al. Among authors: andreozzi f. J Clin Endocrinol Metab. 2005 Sep;90(9):5064-9. doi: 10.1210/jc.2005-0404. Epub 2005 Jun 28. J Clin Endocrinol Metab. 2005. PMID: 15985484
The E23K variant of KCNJ11 encoding the pancreatic beta-cell adenosine 5'-triphosphate-sensitive potassium channel subunit Kir6.2 is associated with an increased risk of secondary failure to sulfonylurea in patients with type 2 diabetes.
Sesti G, Laratta E, Cardellini M, Andreozzi F, Del Guerra S, Irace C, Gnasso A, Grupillo M, Lauro R, Hribal ML, Perticone F, Marchetti P. Sesti G, et al. Among authors: andreozzi f. J Clin Endocrinol Metab. 2006 Jun;91(6):2334-9. doi: 10.1210/jc.2005-2323. Epub 2006 Apr 4. J Clin Endocrinol Metab. 2006. PMID: 16595597
Carotid artery intima-media thickness is associated with insulin-mediated glucose disposal in nondiabetic normotensive offspring of type 2 diabetic patients.
Cardellini M, Marini MA, Frontoni S, Hribal ML, Andreozzi F, Perticone F, Federici M, Lauro D, Sesti G. Cardellini M, et al. Among authors: andreozzi f. Am J Physiol Endocrinol Metab. 2007 Jan;292(1):E347-52. doi: 10.1152/ajpendo.00291.2006. Epub 2006 Sep 12. Am J Physiol Endocrinol Metab. 2007. PMID: 16968812 Free article.
242 results