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Global genetic interaction network of a human cell maps conserved principles and informs functional interpretation of gene co-essentiality profiles.
Billmann M, Costanzo M, Zhang X, Hassan AZ, Rahman M, Brown KR, Chan KS, Tong AHY, Pons C, Ward HN, Ross C, van Leeuwen J, Aregger M, Lawson KA, Mair B, Roth AF, Sen NE, Forster DT, Tan G, Mero P, Masud SN, Lee Y, Aguilera-Uribe M, Ušaj M, Almeida SMT, Aulakh K, Bhojoo U, Birkadze S, Budijono N, Cai X, Caumanns JJ, Chalmers JJ, Chandrashekhar M, Chang D, Climie R, Dasgupta K, Drazic A, Echenique JIR, Gacesa R, Farias AG, Habsid A, Horecka I, Kantautas K, Ji F, Kim DK, Lee SY, Liang W, Lim HJ, Lin K, Lu X, Maier M, Nami B, Nixon A, Mikolajewicz N, Mokhtaridoost M, Nedyalkova L, Rohde T, Rodrigues MS, Soste M, Schultz E, Wang W, Seetharaman A, Shuteriqi E, Sizova O, Taylor DT, Tereshchenko M, Tieu D, Turowec J, Ubhi T, Varland S, Wang KE, Wang ZY, Wei J, Xiao YX, Maass PG, Reversade B, Brown GW, Cravatt BF, Dixon SJ, Wyatt HDM, Röst HL, Roth FP, Xia T, Bader GD, Loewith R, Davis NG, Andrews B, Myers CL, Moffat J, Boone C. Billmann M, et al. Among authors: andrews b. Cell. 2026 Apr 27:S0092-8674(26)00345-4. doi: 10.1016/j.cell.2026.03.044. Online ahead of print. Cell. 2026. PMID: 42049019 Free article.
Charting the genetic interaction map of a cell.
Costanzo M, Baryshnikova A, Myers CL, Andrews B, Boone C. Costanzo M, et al. Among authors: andrews b. Curr Opin Biotechnol. 2011 Feb;22(1):66-74. doi: 10.1016/j.copbio.2010.11.001. Epub 2010 Nov 24. Curr Opin Biotechnol. 2011. PMID: 21111604 Review.
Protein complexes are central in the yeast genetic landscape.
Michaut M, Baryshnikova A, Costanzo M, Myers CL, Andrews BJ, Boone C, Bader GD. Michaut M, et al. PLoS Comput Biol. 2011 Feb;7(2):e1001092. doi: 10.1371/journal.pcbi.1001092. Epub 2011 Feb 24. PLoS Comput Biol. 2011. PMID: 21390331 Free PMC article.
Synthetic Genetic Array Analysis.
Kuzmin E, Costanzo M, Andrews B, Boone C. Kuzmin E, et al. Among authors: andrews b. Cold Spring Harb Protoc. 2016 Apr 1;2016(4):pdb.prot088807. doi: 10.1101/pdb.prot088807. Cold Spring Harb Protoc. 2016. PMID: 27037072
1,168 results