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Pharmacodynamic evaluation of plasma and epithelial lining fluid exposures of amikacin against Pseudomonas aeruginosa in a dynamic in vitro hollow-fibre infection model.
Heffernan AJ, Sime FB, Sarovich DS, Neely M, Guerra-Valero Y, Naicker S, Cottrell K, Harris P, Andrews KT, Ellwood D, Wallis SC, Lipman J, Grimwood K, Roberts JA. Heffernan AJ, et al. Among authors: Andrews KT. Antimicrob Agents Chemother. 2020 Jul 13:AAC.00879-20. doi: 10.1128/AAC.00879-20. Online ahead of print. Antimicrob Agents Chemother. 2020. PMID: 32660986
The science of contemporary street protest: New efforts in the United States.
Fisher DR, Andrews KT, Caren N, Chenoweth E, Heaney MT, Leung T, Perkins LN, Pressman J. Fisher DR, et al. Among authors: Andrews KT. Sci Adv. 2019 Oct 23;5(10):eaaw5461. doi: 10.1126/sciadv.aaw5461. eCollection 2019 Oct. Sci Adv. 2019. PMID: 31681837 Free PMC article. Review.
Cyclization-blocked proguanil as a strategy to improve the antimalarial activity of atovaquone.
Skinner-Adams TS, Fisher GM, Riches AG, Hutt OE, Jarvis KE, Wilson T, von Itzstein M, Chopra P, Antonova-Koch Y, Meister S, Winzeler EA, Clarke M, Fidock DA, Burrows JN, Ryan JH, Andrews KT. Skinner-Adams TS, et al. Among authors: Andrews KT. Commun Biol. 2019 May 3;2:166. doi: 10.1038/s42003-019-0397-3. eCollection 2019. Commun Biol. 2019. PMID: 31069275 Free PMC article.
Proteomic analysis of Plasmodium falciparum histone deacetylase 1 complex proteins.
Engel JA, Norris EL, Gilson P, Przyborski J, Shonhai A, Blatch GL, Skinner-Adams TS, Gorman J, Headlam M, Andrews KT. Engel JA, et al. Among authors: Andrews KT. Exp Parasitol. 2019 Mar;198:7-16. doi: 10.1016/j.exppara.2019.01.008. Epub 2019 Jan 22. Exp Parasitol. 2019. PMID: 30682336
Structure-Activity and Structure-Toxicity Relationships of Peptoid-Based Histone Deacetylase Inhibitors with Dual-Stage Antiplasmodial Activity.
Mackwitz MKW, Hesping E, Antonova-Koch Y, Diedrich D, Woldearegai TG, Skinner-Adams T, Clarke M, Schöler A, Limbach L, Kurz T, Winzeler EA, Held J, Andrews KT, Hansen FK. Mackwitz MKW, et al. Among authors: Andrews KT. ChemMedChem. 2019 May 6;14(9):912-926. doi: 10.1002/cmdc.201800808. Epub 2019 Feb 19. ChemMedChem. 2019. PMID: 30664827 Free PMC article.
Identification of novel quinazoline derivatives as potent antiplasmodial agents.
Bouchut A, Rotili D, Pierrot C, Valente S, Lafitte S, Schultz J, Hoglund U, Mazzone R, Lucidi A, Fabrizi G, Pechalrieu D, Arimondo PB, Skinner-Adams TS, Chua MJ, Andrews KT, Mai A, Khalife J. Bouchut A, et al. Among authors: Andrews KT. Eur J Med Chem. 2019 Jan 1;161:277-291. doi: 10.1016/j.ejmech.2018.10.041. Epub 2018 Oct 17. Eur J Med Chem. 2019. PMID: 30366254
One-pot, multi-component synthesis and structure-activity relationships of peptoid-based histone deacetylase (HDAC) inhibitors targeting malaria parasites.
Diedrich D, Stenzel K, Hesping E, Antonova-Koch Y, Gebru T, Duffy S, Fisher G, Schöler A, Meister S, Kurz T, Avery VM, Winzeler EA, Held J, Andrews KT, Hansen FK. Diedrich D, et al. Among authors: Andrews KT. Eur J Med Chem. 2018 Oct 5;158:801-813. doi: 10.1016/j.ejmech.2018.09.018. Epub 2018 Sep 7. Eur J Med Chem. 2018. PMID: 30245402 Free PMC article.
Correction to Catalyst-Controlled Stereoselective Synthesis Secures the Structure of the Antimalarial Isocyanoterpene Pustulosaisonitrile-1.
White AM, Dao K, Vrubliauskas D, Konst ZA, Pierens GK, Mándi A, Andrews KT, Skinner-Adams TS, Clarke ME, Narbutas PT, Sim DC, Cheney KL, Kurtán T, Garson MJ, Vanderwal CD. White AM, et al. Among authors: Andrews KT. J Org Chem. 2018 Aug 17;83(16):9571-9572. doi: 10.1021/acs.joc.8b01819. Epub 2018 Jul 31. J Org Chem. 2018. PMID: 30062886 No abstract available.
Activity of bromodomain protein inhibitors/binders against asexual-stage Plasmodium falciparum parasites.
Chua MJ, Robaa D, Skinner-Adams TS, Sippl W, Andrews KT. Chua MJ, et al. Among authors: Andrews KT. Int J Parasitol Drugs Drug Resist. 2018 Aug;8(2):189-193. doi: 10.1016/j.ijpddr.2018.03.001. Epub 2018 Mar 26. Int J Parasitol Drugs Drug Resist. 2018. PMID: 29631126 Free PMC article.
Rapid loss of group 1 innate lymphoid cells during blood stage Plasmodium infection.
Ng SS, Souza-Fonseca-Guimaraes F, Rivera FL, Amante FH, Kumar R, Gao Y, Sheel M, Beattie L, Montes de Oca M, Guillerey C, Edwards CL, Faleiro RJ, Frame T, Bunn PT, Vivier E, Godfrey DI, Pellicci DG, Lopez JA, Andrews KT, Huntington ND, Smyth MJ, McCarthy J, Engwerda CR. Ng SS, et al. Among authors: Andrews KT. Clin Transl Immunology. 2018 Jan 12;7(1):e1003. doi: 10.1002/cti2.1003. eCollection 2018. Clin Transl Immunology. 2018. PMID: 29484181 Free PMC article.
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