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1,778 results

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Page 1
Andrographolide: A review of its pharmacology, pharmacokinetics, toxicity and clinical trials and pharmaceutical researches.
Zeng B, Wei A, Zhou Q, Yuan M, Lei K, Liu Y, Song J, Guo L, Ye Q. Zeng B, et al. Phytother Res. 2022 Jan;36(1):336-364. doi: 10.1002/ptr.7324. Epub 2021 Nov 24. Phytother Res. 2022. PMID: 34818697 Review.
Besides, the relationship between the efficacy and security issues of andrographolide should be investigated and evaluated scientifically. In this review, special emphasis is given to andrographolide, a multifunctional natural terpenoids, including its pharmacology, …
Besides, the relationship between the efficacy and security issues of andrographolide should be investigated and evaluated scientific …
Andrographolide alleviates Parkinsonism in MPTP-PD mice via targeting mitochondrial fission mediated by dynamin-related protein 1.
Geng J, Liu W, Gao J, Jiang C, Fan T, Sun Y, Qin ZH, Xu Q, Guo W, Gao J. Geng J, et al. Br J Pharmacol. 2019 Dec;176(23):4574-4591. doi: 10.1111/bph.14823. Epub 2019 Nov 14. Br J Pharmacol. 2019. PMID: 31389613 Free PMC article.
However, the mechanism of how andrographolide protects neurons in Parkinson's disease (PD) remains not fully understood. ...Western blotting, co-immunoprecipitation and immunofluorescence were performed. The target protein of andrographolide was identified by biotin …
However, the mechanism of how andrographolide protects neurons in Parkinson's disease (PD) remains not fully understood. ...Western b …
Andrographolide: Synthetic Methods and Biological Activities.
Hao M, Lv M, Xu H. Hao M, et al. Mini Rev Med Chem. 2020;20(16):1633-1652. doi: 10.2174/1389557520666200429100326. Mini Rev Med Chem. 2020. PMID: 32348215 Review.
Andrographolide, a labdane diterpenoid, is extracted and isolated from the plants of Andrographis paniculata. ...As a continuation, this review aims at giving an overview of the recent advances (from 2015 to 2018) of andrographolide and its derivatives with regard t …
Andrographolide, a labdane diterpenoid, is extracted and isolated from the plants of Andrographis paniculata. ...As a continuation, t …
Andrographolide: A Review of Analytical Methods.
Patil R, Jain V. Patil R, et al. J Chromatogr Sci. 2021 Jan 14;59(2):191-203. doi: 10.1093/chromsci/bmaa091. J Chromatogr Sci. 2021. PMID: 33221827 Review.
Bicyclic diterpenoid lactone andrographolide is regarded as a "natural antibiotic" as it is known to exhibit a range of bioactivities including anti-inflammatory, antibacterial, antipyretic, antineoplastic, cardioprotective, hepatoprotective and hypoglycaemic, and is prese …
Bicyclic diterpenoid lactone andrographolide is regarded as a "natural antibiotic" as it is known to exhibit a range of bioactivities …
Andrographolide: Chemical modification and its effect on biological activities.
Kumar G, Singh D, Tali JA, Dheer D, Shankar R. Kumar G, et al. Bioorg Chem. 2020 Jan;95:103511. doi: 10.1016/j.bioorg.2019.103511. Epub 2019 Dec 17. Bioorg Chem. 2020. PMID: 31884143 Review.
Many reports are available related to Andrographolide (1) but a consolidated review on the chemical modification of andrographolide with special emphasis on its different functional groups with respect to their biological activities is still missing from the previou …
Many reports are available related to Andrographolide (1) but a consolidated review on the chemical modification of andrographolid …
Overview of pharmacological activities of Andrographis paniculata and its major compound andrographolide.
Dai Y, Chen SR, Chai L, Zhao J, Wang Y, Wang Y. Dai Y, et al. Crit Rev Food Sci Nutr. 2019;59(sup1):S17-S29. doi: 10.1080/10408398.2018.1501657. Epub 2018 Sep 10. Crit Rev Food Sci Nutr. 2019. PMID: 30040451
In this article, we comprehensively review the therapeutic potential of A. paniculata and andrographolide focusing on the mechanisms of action and clinical application. We systemically discuss the structure-activity relationship of andrographolide and derivatives. D …
In this article, we comprehensively review the therapeutic potential of A. paniculata and andrographolide focusing on the mechanisms …
Andrographolide and its derivatives: Current achievements and future perspectives.
Zhang H, Li S, Si Y, Xu H. Zhang H, et al. Eur J Med Chem. 2021 Nov 15;224:113710. doi: 10.1016/j.ejmech.2021.113710. Epub 2021 Jul 20. Eur J Med Chem. 2021. PMID: 34315039 Review.
Based on extensive chemical structural modifications, a series of andrographolide derivatives with improved bioavailability and druggability has been developed. ...We believe that this review paper will benefit drug discovery where andrographolide was used as a temp …
Based on extensive chemical structural modifications, a series of andrographolide derivatives with improved bioavailability and drugg …
Andrographolide as a potent and promising antiviral agent.
Latif R, Wang CY. Latif R, et al. Chin J Nat Med. 2020 Oct;18(10):760-769. doi: 10.1016/S1875-5364(20)60016-4. Chin J Nat Med. 2020. PMID: 33039055 Review.
Andrographolide is a labdane diterpenoid extracted and purified from the aerial parts of plants belonging to genus Andrographis (Acanthaceae). ...This paper aims to highlight the antiviral role of Andrographolide that can made significant contributions toward the im …
Andrographolide is a labdane diterpenoid extracted and purified from the aerial parts of plants belonging to genus Andrographis (Acan …
Andrographolide and its derivatives are effective compounds for gastrointestinal protection: a review.
Wang DW, Xiang YJ, Wei ZL, Yao H, Shen T. Wang DW, et al. Eur Rev Med Pharmacol Sci. 2021 Mar;25(5):2367-2382. doi: 10.26355/eurrev_202103_25276. Eur Rev Med Pharmacol Sci. 2021. PMID: 33755974 Free article. Review.
MATERIALS AND METHODS: The data in this review are searched and selected from PubMed with the keywords: Andrographolide and Andrographolide derivatives, and relevant data with gastrointestinal protection are extracted and discussed. ...CONCLUSIONS: Andrographolid …
MATERIALS AND METHODS: The data in this review are searched and selected from PubMed with the keywords: Andrographolide and Androg …
Andrographolide and its Derivatives in Cardiovascular Disease: A Comprehensive Review.
Zhang S, Xie X, Zhao J, Jiang Y, Huang C, Li Q, Xia B, Yin L, Yuan X, You Q. Zhang S, et al. Planta Med. 2025 Apr;91(5):259-270. doi: 10.1055/a-2542-0756. Epub 2025 Mar 7. Planta Med. 2025. PMID: 40054492 Free article. Review.
This review provides a comprehensive overview of the effects of andrographolide on cardiovascular disease and examines its essential roles and mechanisms in cardiovascular disease and other vascular dysfunctions. The data collected in this review serve as a comprehensive r …
This review provides a comprehensive overview of the effects of andrographolide on cardiovascular disease and examines its essential …
1,778 results