Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2016 1
2017 1
2019 1
2020 2
2021 4
2022 3
2023 5
2024 4
2025 10
2026 0

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

28 results

Results by year

Filters applied: . Clear all
Page 1
Deep Red Blood Cell Proteome Defines the Band 3 N-Terminus Interactome as a Regulator of Hypoxic Adaptation via BLVRB-Dependent S -Nitroso Transfer.
Issaian AV, Dzieciatkowska M, Bevers S, Zohreh S, Hay A, Saviola A, Redzic JS, Reisz JA, Keele GR, Cendali FI, Haiman ZB, Nemkov T, Stephenson D, Lisk C, Vallese F, Palsson BO, King SB, Page GP, Doctor A, Hudson K, Hansen KC, Irwin DC, Mohandas N, Zimring JC, Eisenmesser EZ, D'Alessandro A. Issaian AV, et al. Among authors: d alessandro a. bioRxiv [Preprint]. 2025 Nov 30:2025.11.29.691178. doi: 10.1101/2025.11.29.691178. bioRxiv. 2025. PMID: 41394639 Free PMC article. Preprint.
In humanized mice, truncation of the Band 3 N-terminus disrupted glycolytic activation, reduced 2,3-bisphosphoglycerate synthesis, and impaired exercise tolerance despite preserved cardiopulmonary function, establishing the physiological relevance of this module. ...HIGHLI …
In humanized mice, truncation of the Band 3 N-terminus disrupted glycolytic activation, reduced 2,3-bisphosphoglycerate synthesis, and impai …
Age-related decline of chaperone-mediated autophagy in skeletal muscle leads to progressive myopathy.
Santiago-Fernández O, Coletto L, Tasset I, Kaushik S, Concepcion AR, Qaisar R, Macho-González A, Lindenau K, Diaz A, Khawaja RR, Donega S, Banskota N, Ubaida-Mohien C, Pharaoh G, Ahn B, Hartnell LM, Ramírez-Pardo I, Chavda B, Gazteluiturri A, Kinter M, Ferrucci L, Reisz JA, D'Alessandro A, Van Remmen H, Muñoz-Cánoves P, Feske S, Cuervo AM. Santiago-Fernández O, et al. Among authors: d alessandro a. Nat Metab. 2025 Dec;7(12):2589-2611. doi: 10.1038/s42255-025-01412-9. Epub 2025 Dec 3. Nat Metab. 2025. PMID: 41339969 Free PMC article.
We show that CMA is upregulated in skeletal muscle in response to starvation, exercise and tissue repair, but declines in ageing and obesity. Using a muscle-specific CMA-deficient mouse model, we show that CMA loss leads to progressive myopathy, including reduced muscle fo …
We show that CMA is upregulated in skeletal muscle in response to starvation, exercise and tissue repair, but declines in ageing and …
Increased Exercise Tolerance in G6PD African Variant Mice Driven by Metabolic Adaptations and Erythrophagocytosis.
Cendali FI, Grier AL, Lisk C, Dzieciatkowska M, Haiman Z, Reisz JA, Harral J, Stephenson D, Hay AM, Wartchow EP, Buehler PW, Hansen KC, Nemkov T, Zimring JC, Irwin DC, D'Alessandro A. Cendali FI, et al. Among authors: d alessandro a. Antioxidants (Basel). 2025 Jul 29;14(8):927. doi: 10.3390/antiox14080927. Antioxidants (Basel). 2025. PMID: 40867824 Free PMC article.
Glucose-6-phosphate dehydrogenase (G6PD) deficiency, the most common enzymatic disorder, affects over 500 million people worldwide and is often linked to exercise intolerance due to oxidative stress, but its true impact on physical performance remains unclear. ...Given tha …
Glucose-6-phosphate dehydrogenase (G6PD) deficiency, the most common enzymatic disorder, affects over 500 million people worldwide and is of …
Erythrocyte Glycolytic and Redox Metabolism Affects Muscle Oxygenation and Exercise Performance: A Randomized Double-Blind Crossover Study in Men.
Chatzinikolaou PN, Margaritelis NV, Paschalis V, Theodorou AA, Moushi E, Vrabas IS, Kyparos A, Fatouros IG, D'Alessandro A, Nikolaidis MG. Chatzinikolaou PN, et al. Among authors: d alessandro a. Sports Med. 2025 Dec;55(12):3157-3181. doi: 10.1007/s40279-025-02279-2. Epub 2025 Jul 28. Sports Med. 2025. PMID: 40719977 Free PMC article. Clinical Trial.
Oxidative stress increased erythrocyte glycolytic flux by + 53%, while arm exercise further increased glycolytic flux in both control (+ 200%) and oxidative stress (+ 86%) conditions. ...Oxidative stress decreased arm deoxygenated hemoglobin by - 7.4% during arm exercis …
Oxidative stress increased erythrocyte glycolytic flux by + 53%, while arm exercise further increased glycolytic flux in both control …
Metabolic insights into hypoxia adaptation in adolescent athletes at different altitudes: a cross-sectional study.
Sánchez CAR, Pardo-Rodriguez D, Mancera-Soto E, León L, Paulucio D, D'Alessandro A, Santos CGM, Cristancho E, Monnerat G, Ramos-Caballero DM, Cala MP, Pompeu F. Sánchez CAR, et al. Among authors: d alessandro a. Front Mol Biosci. 2025 May 9;12:1571103. doi: 10.3389/fmolb.2025.1571103. eCollection 2025. Front Mol Biosci. 2025. PMID: 40417063 Free PMC article.
Physiologic relevance of the transpulmonary metabolome in connective tissue disease-associated pulmonary vascular disease.
Lee MH, Menezes TCF, Reisz JA, Cendali FI, Ferreira EVM, Ota-Arakaki JS, Sperandio PA, Kumar R, Mickael C, Ieong MM, Santos JL, Duarte ACB, Fonseca Balladares DC, Nolan K, Tuder RM, Hassoun PM, D'Alessandro A, Oliveira RKF, Graham BB. Lee MH, et al. Among authors: d alessandro a. JCI Insight. 2025 May 8;10(9):e187911. doi: 10.1172/jci.insight.187911. eCollection 2025 May 8. JCI Insight. 2025. PMID: 40337861 Free PMC article.
We hypothesized that metabolite quantification across the pulmonary vascular bed in connective tissue disease-associated (CTD-associated) PAH would identify transpulmonary gradients of pathobiologically relevant metabolites, in an exercise stage-specific manner. Sixty-thre …
We hypothesized that metabolite quantification across the pulmonary vascular bed in connective tissue disease-associated (CTD-associated) PA …
Long-Distance Trail Running Induces Inflammatory-Associated Protein, Lipid, and Purine Oxidation in Red Blood Cells.
Nemkov T, Stauffer E, Cendali F, Stephenson D, Nader E, Robert M, Skinner S, Dzieciatkowska M, Hansen KC, Robach P, Millet GY, Connes P, D'Alessandro A. Nemkov T, et al. Among authors: d alessandro a. bioRxiv [Preprint]. 2025 May 19:2025.04.09.648006. doi: 10.1101/2025.04.09.648006. bioRxiv. 2025. PMID: 40291720 Free PMC article. Preprint.
Ultra-endurance exercise places extreme physiological demands on oxygen transport, yet its impact on red blood cells (RBCs) remains underexplored. ...These findings challenge the assumption that RBC damage in endurance exercise is primarily mechanical, revealing sys …
Ultra-endurance exercise places extreme physiological demands on oxygen transport, yet its impact on red blood cells (RBCs) remains u …
Red Blood Cell Metabolic Responses during Acute Hypoxic Exercise in Healthy Adults.
Forbes LM, Cendali FI, Nemkov T, Bull TM, D'Alessandro A, Rawlinson KE, Roach RC, Subudhi AW, Lahm T, Cornwell WK 3rd. Forbes LM, et al. Among authors: d alessandro a. Am J Respir Cell Mol Biol. 2025 Apr;72(4):456-459. doi: 10.1165/rcmb.2024-0178LE. Am J Respir Cell Mol Biol. 2025. PMID: 40167309 No abstract available.
Targeting lung heme iron by aerosol hemopexin adminstration in sickle cell disease pulmonary hypertension.
Lucero MJ, Lisk C, Cendali F, Swindle D, Setua S, Thangaraju K, Pak DI, O'Boyle Q, Lu S, Tolson R, Zaeske S, Rana N, Khan S, Westover N, DavizonCastillo P, George G, Hassell K, Nuss R, Brinkman N, Gentinetta T, Palmer AF, D'Alessandro A, Buehler PW, Irwin DC. Lucero MJ, et al. Among authors: d alessandro a. Free Radic Biol Med. 2025 Mar 1;229:458-473. doi: 10.1016/j.freeradbiomed.2025.01.045. Epub 2025 Jan 23. Free Radic Biol Med. 2025. PMID: 39862998 Free article.
Herein, we evaluated in a murine model of hemolysis driven SCD-PH, if intrapulmonary Hpx administration bi-weekly for 10 weeks improves lung iron deposition, exercise tolerance, cardiovascular function, and multi-omic indices associated with SCD-PH. ...Hpx extravasates int …
Herein, we evaluated in a murine model of hemolysis driven SCD-PH, if intrapulmonary Hpx administration bi-weekly for 10 weeks improves lung …
Identification of candidate biomarkers and molecular networks associated with Pulmonary Arterial Hypertension using machine learning and plasma multi-Omics analysis.
Kheyfets VO, Sweatt AJ, Zhang H, Nemkov T, Heerdt P, Dzieciatkowska M, Stephenson D, LaCroix IS, D'Alessandro A, Oldham WM, Hansen K, Zamanian RT, Stenmark KR. Kheyfets VO, et al. Among authors: d alessandro a. medRxiv [Preprint]. 2024 Dec 20:2024.12.17.24319117. doi: 10.1101/2024.12.17.24319117. medRxiv. 2024. PMID: 39763543 Free PMC article. Preprint.
This model stratified patients into risk categories consistent with established markers of cardiac function, exercise tolerance, and the REVEAL 2.0 risk score. CONCLUSION: This study underscores the utility of integrated omics in unraveling PAH pathobiology in human subjec …
This model stratified patients into risk categories consistent with established markers of cardiac function, exercise tolerance, and …
28 results