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Editor's Highlight: Mechanistic Toxicity Tests Based on an Adverse Outcome Pathway Network for Hepatic Steatosis.
Angrish MM, McQueen CA, Cohen-Hubal E, Bruno M, Ge Y, Chorley BN. Angrish MM, et al. Toxicol Sci. 2017 Sep 1;159(1):159-169. doi: 10.1093/toxsci/kfx121. Toxicol Sci. 2017. PMID: 28903485
Aryl hydrocarbon receptor-mediated induction of Stearoyl-CoA desaturase 1 alters hepatic fatty acid composition in TCDD-elicited steatosis.
Angrish MM, Jones AD, Harkema JR, Zacharewski TR. Angrish MM, et al. Toxicol Sci. 2011 Dec;124(2):299-310. doi: 10.1093/toxsci/kfr226. Epub 2011 Sep 2. Toxicol Sci. 2011. PMID: 21890736 Free PMC article.
Dietary fat is a lipid source in 2,3,7,8-tetrachlorodibenzo-ρ-dioxin (TCDD)-elicited hepatic steatosis in C57BL/6 mice.
Angrish MM, Mets BD, Jones AD, Zacharewski TR. Angrish MM, et al. Toxicol Sci. 2012 Aug;128(2):377-86. doi: 10.1093/toxsci/kfs155. Epub 2012 Apr 26. Toxicol Sci. 2012. PMID: 22539624 Free PMC article.
TCDD-elicited effects on liver, serum, and adipose lipid composition in C57BL/6 mice.
Angrish MM, Dominici CY, Zacharewski TR. Angrish MM, et al. Toxicol Sci. 2013 Jan;131(1):108-15. doi: 10.1093/toxsci/kfs277. Epub 2012 Sep 13. Toxicol Sci. 2013. PMID: 22977169 Free PMC article.
Comparative analysis of temporal and dose-dependent TCDD-elicited gene expression in human, mouse, and rat primary hepatocytes.
Forgacs AL, Dere E, Angrish MM, Zacharewski TR. Forgacs AL, et al. Among authors: angrish mm. Toxicol Sci. 2013 May;133(1):54-66. doi: 10.1093/toxsci/kft028. Epub 2013 Feb 15. Toxicol Sci. 2013. PMID: 23418086 Free PMC article.
Probe molecule (PrM) approach in adverse outcome pathway (AOP) based high-throughput screening (HTS): in vivo discovery for developing in vitro target methods.
Angrish MM, Madden MC, Pleil JD. Angrish MM, et al. Chem Res Toxicol. 2015 Apr 20;28(4):551-9. doi: 10.1021/acs.chemrestox.5b00024. Epub 2015 Mar 4. Chem Res Toxicol. 2015. PMID: 25692543
Integrating Publicly Available Data to Generate Computationally Predicted Adverse Outcome Pathways for Fatty Liver.
Bell SM, Angrish MM, Wood CE, Edwards SW. Bell SM, et al. Among authors: angrish mm. Toxicol Sci. 2016 Apr;150(2):510-20. doi: 10.1093/toxsci/kfw017. Epub 2016 Feb 19. Toxicol Sci. 2016. PMID: 26895641
Taxonomic applicability of inflammatory cytokines in adverse outcome pathway (AOP) development.
Angrish MM, Pleil JD, Stiegel MA, Madden MC, Moser VC, Herr DW. Angrish MM, et al. J Toxicol Environ Health A. 2016;79(4):184-96. doi: 10.1080/15287394.2016.1138923. Epub 2016 Feb 25. J Toxicol Environ Health A. 2016. PMID: 26914248
Tipping the Balance: Hepatotoxicity and the 4 Apical Key Events of Hepatic Steatosis.
Angrish MM, Kaiser JP, McQueen CA, Chorley BN. Angrish MM, et al. Toxicol Sci. 2016 Apr;150(2):261-8. doi: 10.1093/toxsci/kfw018. Epub 2016 Mar 15. Toxicol Sci. 2016. PMID: 26980302 Review.
Adverse outcome pathways: a concise introduction for toxicologists.
Vinken M, Knapen D, Vergauwen L, Hengstler JG, Angrish M, Whelan M. Vinken M, et al. Arch Toxicol. 2017 Nov;91(11):3697-3707. doi: 10.1007/s00204-017-2020-z. Epub 2017 Jun 28. Arch Toxicol. 2017. PMID: 28660287 Free PMC article. Review.
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