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Coinhibition of topoisomerase 1 and BRD4-mediated pause release selectively kills pancreatic cancer via readthrough transcription.
Cameron DP, Grosser J, Ladigan S, Kuzin V, Iliopoulou E, Wiegard A, Benredjem H, Jackson K, Liffers ST, Lueong S, Cheung PF, Vangala D, Pohl M, Viebahn R, Teschendorf C, Wolters H, Usta S, Geng K, Kutter C, Arsenian-Henriksson M, Siveke JT, Tannapfel A, Schmiegel W, Hahn SA, Baranello L. Cameron DP, et al. Among authors: wiegard a. Sci Adv. 2023 Oct 13;9(41):eadg5109. doi: 10.1126/sciadv.adg5109. Epub 2023 Oct 13. Sci Adv. 2023. PMID: 37831776 Free PMC article.
Diversity of KaiC-based timing systems in marine Cyanobacteria.
Axmann IM, Hertel S, Wiegard A, Dörrich AK, Wilde A. Axmann IM, et al. Among authors: wiegard a. Mar Genomics. 2014 Apr;14:3-16. doi: 10.1016/j.margen.2013.12.006. Epub 2014 Jan 3. Mar Genomics. 2014. PMID: 24388874 Free article. Review.
Two KaiABC systems control circadian oscillations in one cyanobacterium.
Köbler C, Schmelling NM, Wiegard A, Pawlowski A, Pattanayak GK, Spät P, Scheurer NM, Sebastian KN, Stirba FP, Berwanger LC, Kolkhof P, Maček B, Rust MJ, Axmann IM, Wilde A. Köbler C, et al. Among authors: wiegard a. Nat Commun. 2024 Sep 3;15(1):7674. doi: 10.1038/s41467-024-51914-5. Nat Commun. 2024. PMID: 39227593 Free PMC article.
Minimal tool set for a prokaryotic circadian clock.
Schmelling NM, Lehmann R, Chaudhury P, Beck C, Albers SV, Axmann IM, Wiegard A. Schmelling NM, et al. Among authors: wiegard a. BMC Evol Biol. 2017 Jul 21;17(1):169. doi: 10.1186/s12862-017-0999-7. BMC Evol Biol. 2017. PMID: 28732467 Free PMC article.
12 results