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Vascular endothelial growth factor-B acts as a coronary growth factor in transgenic rats without inducing angiogenesis, vascular leak, or inflammation.
Bry M, Kivelä R, Holopainen T, Anisimov A, Tammela T, Soronen J, Silvola J, Saraste A, Jeltsch M, Korpisalo P, Carmeliet P, Lemström KB, Shibuya M, Ylä-Herttuala S, Alhonen L, Mervaala E, Andersson LC, Knuuti J, Alitalo K. Bry M, et al. Among authors: anisimov a. Circulation. 2010 Oct 26;122(17):1725-33. doi: 10.1161/CIRCULATIONAHA.110.957332. Epub 2010 Oct 11. Circulation. 2010. PMID: 20937974
VEGF-B-induced vascular growth leads to metabolic reprogramming and ischemia resistance in the heart.
Kivelä R, Bry M, Robciuc MR, Räsänen M, Taavitsainen M, Silvola JM, Saraste A, Hulmi JJ, Anisimov A, Mäyränpää MI, Lindeman JH, Eklund L, Hellberg S, Hlushchuk R, Zhuang ZW, Simons M, Djonov V, Knuuti J, Mervaala E, Alitalo K. Kivelä R, et al. Among authors: anisimov a. EMBO Mol Med. 2014 Mar;6(3):307-21. doi: 10.1002/emmm.201303147. Epub 2014 Jan 21. EMBO Mol Med. 2014. PMID: 24448490 Free PMC article.
Endothelial Bmx tyrosine kinase activity is essential for myocardial hypertrophy and remodeling.
Holopainen T, Räsänen M, Anisimov A, Tuomainen T, Zheng W, Tvorogov D, Hulmi JJ, Andersson LC, Cenni B, Tavi P, Mervaala E, Kivelä R, Alitalo K. Holopainen T, et al. Among authors: anisimov a. Proc Natl Acad Sci U S A. 2015 Oct 20;112(42):13063-8. doi: 10.1073/pnas.1517810112. Epub 2015 Oct 1. Proc Natl Acad Sci U S A. 2015. PMID: 26430242 Free PMC article.
Vascular Endothelial Growth Factor-B Overexpressing Hearts Are Not Protected From Transplant-Associated Ischemia-Reperfusion Injury.
Raissadati A, Tuuminen R, Dashkevich A, Bry M, Kivelä R, Anisimov A, Syrjälä S, Arnaudova R, Rouvinen E, Keränen MA, Krebs R, Nykänen AI, Lemström KB. Raissadati A, et al. Among authors: anisimov a. Exp Clin Transplant. 2017 Apr;15(2):203-212. doi: 10.6002/ect.2016.0181. Epub 2016 Sep 1. Exp Clin Transplant. 2017. PMID: 27588416 Free article.
The SARS-CoV-2 receptor ACE2 is expressed in mouse pericytes but not endothelial cells: Implications for COVID-19 vascular research.
Muhl L, He L, Sun Y, Andaloussi Mäe M, Pietilä R, Liu J, Genové G, Zhang L, Xie Y, Leptidis S, Mocci G, Stritt S, Osman A, Anisimov A, Hemanthakumar KA, Räsänen M, Hansson EM, Björkegren J, Vanlandewijck M, Blomgren K, Mäkinen T, Peng XR, Hu Y, Ernfors P, Arnold TD, Alitalo K, Lendahl U, Betsholtz C. Muhl L, et al. Among authors: anisimov a. Stem Cell Reports. 2022 May 10;17(5):1089-1104. doi: 10.1016/j.stemcr.2022.03.016. Epub 2022 Apr 21. Stem Cell Reports. 2022. PMID: 35452595 Free PMC article.
The angiopoietin receptor Tie2 is atheroprotective in arterial endothelium.
Anisimov A, Fang S, Hemanthakumar KA, Örd T, van Avondt K, Chevre R, Toropainen A, Singha P, Gilani H, Nguyen SD, Karaman S, Korhonen EA, Adams RH, Augustin HG, Öörni K, Soehnlein O, Kaikkonen MU, Alitalo K. Anisimov A, et al. Nat Cardiovasc Res. 2023 Mar 13;2(3):307-321. doi: 10.1038/s44161-023-00224-y. Nat Cardiovasc Res. 2023. PMID: 37476204 Free PMC article.
Vascular endothelial growth factor-angiopoietin chimera with improved properties for therapeutic angiogenesis.
Anisimov A, Tvorogov D, Alitalo A, Leppänen VM, An Y, Han EC, Orsenigo F, Gaál EI, Holopainen T, Koh YJ, Tammela T, Korpisalo P, Keskitalo S, Jeltsch M, Ylä-Herttuala S, Dejana E, Koh GY, Choi C, Saharinen P, Alitalo K. Anisimov A, et al. Circulation. 2013 Jan 29;127(4):424-34. doi: 10.1161/CIRCULATIONAHA.112.127472. Circulation. 2013. PMID: 23357661
330 results