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Impaired pressor sensitivity to noradrenaline in septic shock patients with and without impaired adrenal function reserve
Annane D, et al. Br J Clin Pharmacol 1998 - Clinical Trial. PMID 9862249 Free PMC article.
RESULTS: As compared with controls, patients with septic shock had increased basal cortisol levels (mean+/-s.d.: 1564+/-818 vs 378+/-104 nmol l(-1) , P=0.002, 95% confidence interval for difference in means: [452, 1920]) and a blunted cortisol response to corticotrophin (403+/-461 vs 1132+/-195 nmol l(-1), P=0.008, [-1163, -2951). ...
RESULTS: As compared with controls, patients with septic shock had increased basal cortisol levels (mean+/-s.d.: 1564+/-818 vs 378+/- …
Corticosteroids for septic shock
Annane D. Crit Care Med 2001 - Review. PMID 11445745
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