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The tyrosine kinase FRK/RAK participates in cytokine-induced islet cell cytotoxicity.
Welsh M, Welsh C, Ekman M, Dixelius J, Hägerkvist R, Annerén C, Akerblom B, Mahboobi S, Chandrasekharan S, Liu ET. Welsh M, et al. Biochem J. 2004 Aug 15;382(Pt 1):261-8. doi: 10.1042/BJ20040285. Biochem J. 2004. PMID: 15186217 Free PMC article.
No evidence for in vitro phosphorylation of the C-terminal regulatory sites Tyr-497 and Tyr-504 was obtained, nor was there any indication of in vitro regulation of FRK/RAK kinase activity. ...
No evidence for in vitro phosphorylation of the C-terminal regulatory sites Tyr-497 and Tyr-504 was obtained, nor was there any indic …
Tyrosine kinase signalling in embryonic stem cells.
Annerén C. Annerén C. Clin Sci (Lond). 2008 Jul;115(2):43-55. doi: 10.1042/CS20070388. Clin Sci (Lond). 2008. PMID: 18547167 Review.
A role of FRK in regulation of embryonal pancreatic beta cell formation.
Akerblom B, Annerén C, Welsh M. Akerblom B, et al. Mol Cell Endocrinol. 2007 May 30;270(1-2):73-8. doi: 10.1016/j.mce.2007.02.009. Epub 2007 Feb 25. Mol Cell Endocrinol. 2007. PMID: 17416457
Glucose intolerance and reduced islet blood flow in transgenic mice expressing the FRK tyrosine kinase under the control of the rat insulin promoter.
Annerén C, Welsh M, Jansson L. Annerén C, et al. Am J Physiol Endocrinol Metab. 2007 Apr;292(4):E1183-90. doi: 10.1152/ajpendo.00168.2006. Epub 2006 Dec 19. Am J Physiol Endocrinol Metab. 2007. PMID: 17179392
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