Anonymising and sharing individual patient data.
BMJ. 2015.
PMID: 25794882
Free PMC article.
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anonymizing and sharing individual patient data
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Anonymising and sharing individual patient data.
BMJ. 2015 Mar 20;350:h1139. doi: 10.1136/bmj.h1139.
BMJ. 2015.
PMID: 25794882
Free PMC article.
There is a strong movement to share individual patient data for secondary purposes, particularly for research. A major obstacle to broad data sharing has been the concern for patient privacy. One of the methods for protecting the p …
There is a strong movement to share individual patient data for secondary purposes, particularly for research. A …
Preparing individual patient data from clinical trials for sharing: the GlaxoSmithKline approach.
Pharm Stat. 2014 May-Jun;13(3):179-83. doi: 10.1002/pst.1615. Epub 2014 Mar 25.
Pharm Stat. 2014.
PMID: 24668938
In May 2013, GlaxoSmithKline (980 Great West Road, Brentford, Middlesex, TW8 9GS, UK) established a new online system to enable scientific researchers to request access to anonymised patient level clinical trial data. Providing access to individual …
In May 2013, GlaxoSmithKline (980 Great West Road, Brentford, Middlesex, TW8 9GS, UK) established a new online system to enable scientific r …
Phase III, multicentre, randomised, double-blind, placebo-controlled, 104-week study of subcutaneous belimumab administered in combination with rituximab in adults with systemic lupus erythematosus (SLE): BLISS-BELIEVE study protocol.
BMJ Open. 2019 Mar 20;9(3):e025687. doi: 10.1136/bmjopen-2018-025687.
BMJ Open. 2019.
PMID: 30898822
Free PMC article.
Major secondary efficacy endpoints are the proportion of patients in clinical remission (defined as SLEDAI-2K=0, without immunosuppressants and corticosteroids) at week 64, and the proportion of patients with disease control at week 104. Safety endpoints include the …
Major secondary efficacy endpoints are the proportion of patients in clinical remission (defined as SLEDAI-2K=0, without immunosuppre …
Response to physical rehabilitation and recovery trajectories following critical illness: individual participant data meta-analysis protocol.
BMJ Open. 2020 May 4;10(5):e035613. doi: 10.1136/bmjopen-2019-035613.
BMJ Open. 2020.
PMID: 32371516
Free PMC article.
Principal investigators of eligible trials were invited to contribute their data to this individual participant data meta-analysis. Risk of bias will be assessed (Cochrane risk of bias tool for randomised trials). ...Multiple imputation using chained equation …
Principal investigators of eligible trials were invited to contribute their data to this individual participant data me …
Sharing individual participant data from clinical trials: an opinion survey regarding the establishment of a central repository.
PLoS One. 2014 May 29;9(5):e97886. doi: 10.1371/journal.pone.0097886. eCollection 2014.
PLoS One. 2014.
PMID: 24874700
Free PMC article.
BACKGROUND: Calls have been made for increased access to individual participant data (IPD) from clinical trials, to ensure that complete evidence is available. ...Restricted access requiring approval, data security, anonymisation of data, and ov …
BACKGROUND: Calls have been made for increased access to individual participant data (IPD) from clinical trials, to ensure tha …
Ibuprofen versus fosfomycin for uncomplicated urinary tract infection in women: randomised controlled trial.
BMJ. 2015 Dec 23;351:h6544. doi: 10.1136/bmj.h6544.
BMJ. 2015.
PMID: 26698878
Free PMC article.
Clinical Trial.
Initial symptomatic treatment is a possible approach to be discussed with women willing to avoid immediate antibiotics and to accept a somewhat higher burden of symptoms. FUNDING, COMPETING INTERESTS, DATA SHARING: German Federal Ministry of Education and Research ( …
Initial symptomatic treatment is a possible approach to be discussed with women willing to avoid immediate antibiotics and to accept a somew …
The prognostic profile of subfertile couples and treatment outcome after expectant management, intrauterine insemination and in vitro fertilisation: a study protocol for the meta-analysis of individual patient data.
BJOG. 2012 Jul;119(8):953-7. doi: 10.1111/j.1471-0528.2012.03343.x. Epub 2012 May 18.
BJOG. 2012.
PMID: 22607482
Free article.
Review.
Individual patient data analyses allow us to take these prognostic factors into account, and to evaluate their effect on treatment outcome. This study aims to use anonymised data from relevant published trials to perform an individual …
Individual patient data analyses allow us to take these prognostic factors into account, and to evaluate their effect o …
Data protection and ethics requirements for multisite research with health data: a comparative examination of legislative governance frameworks and the role of data protection technologies.
J Law Biosci. 2020 May 6;7(1):lsaa010. doi: 10.1093/jlb/lsaa010. eCollection 2020 Jan-Jun.
J Law Biosci. 2020.
PMID: 32733683
Free PMC article.
However, patient health data must be shared between institutions and across jurisdictions for the benefits of personalised medicine to be realised. Whilst data protection, privacy, and research ethics laws protect patient confidentiality and saf …
However, patient health data must be shared between institutions and across jurisdictions for the benefits of personali …
Health Data Linkage for UK Public Interest Research: Key Obstacles and Solutions.
Int J Popul Data Sci. 2019 Apr 2;4(1):1093. doi: 10.23889/ijpds.v4i1.1093.
Int J Popul Data Sci. 2019.
PMID: 32935027
Free PMC article.
APPROACH: We focus on three UK infrastructures set up to link and share data for research: the Administrative Data Research Network, NHS Digital, and the Secure Anonymised Information Linkage Databank. Bringing an interdisciplinary perspective, we iden …
APPROACH: We focus on three UK infrastructures set up to link and share data for research: the Administrative Data Rese …
Arthroscopic meniscectomy versus non-surgical or sham treatment in patients with MRI confirmed degenerative meniscus lesions: a protocol for an individual participant data meta-analysis.
BMJ Open. 2020 Mar 8;10(3):e031864. doi: 10.1136/bmjopen-2019-031864.
BMJ Open. 2020.
PMID: 32152157
Free PMC article.
All individual participant data will be validated for missing data, internal data consistency, randomisation integrity and censoring patterns. ...Other outcomes of interest will include the difference in adverse events and mental health. ETHICS AND DIS …
All individual participant data will be validated for missing data, internal data consistency, randomisation int …