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The DUX4 gene at the FSHD1A locus encodes a pro-apoptotic protein.
Kowaljow V, Marcowycz A, Ansseau E, Conde CB, Sauvage S, Mattéotti C, Arias C, Corona ED, Nuñez NG, Leo O, Wattiez R, Figlewicz D, Laoudj-Chenivesse D, Belayew A, Coppée F, Rosa AL. Kowaljow V, et al. Among authors: ansseau e. Neuromuscul Disord. 2007 Aug;17(8):611-23. doi: 10.1016/j.nmd.2007.04.002. Epub 2007 Jun 27. Neuromuscul Disord. 2007. PMID: 17588759
DUX4, a candidate gene of facioscapulohumeral muscular dystrophy, encodes a transcriptional activator of PITX1.
Dixit M, Ansseau E, Tassin A, Winokur S, Shi R, Qian H, Sauvage S, Mattéotti C, van Acker AM, Leo O, Figlewicz D, Barro M, Laoudj-Chenivesse D, Belayew A, Coppée F, Chen YW. Dixit M, et al. Among authors: ansseau e. Proc Natl Acad Sci U S A. 2007 Nov 13;104(46):18157-62. doi: 10.1073/pnas.0708659104. Epub 2007 Nov 5. Proc Natl Acad Sci U S A. 2007. PMID: 17984056 Free PMC article.
The Krüppel-like factor 15 as a molecular link between myogenic factors and a chromosome 4q transcriptional enhancer implicated in facioscapulohumeral dystrophy.
Dmitriev P, Petrov A, Ansseau E, Stankevicins L, Charron S, Kim E, Bos TJ, Robert T, Turki A, Coppée F, Belayew A, Lazar V, Carnac G, Laoudj D, Lipinski M, Vassetzky YS. Dmitriev P, et al. Among authors: ansseau e. J Biol Chem. 2011 Dec 30;286(52):44620-31. doi: 10.1074/jbc.M111.254052. Epub 2011 Sep 21. J Biol Chem. 2011. PMID: 21937448 Free PMC article.
The FSHD atrophic myotube phenotype is caused by DUX4 expression.
Vanderplanck C, Ansseau E, Charron S, Stricwant N, Tassin A, Laoudj-Chenivesse D, Wilton SD, Coppée F, Belayew A. Vanderplanck C, et al. Among authors: ansseau e. PLoS One. 2011;6(10):e26820. doi: 10.1371/journal.pone.0026820. Epub 2011 Oct 28. PLoS One. 2011. PMID: 22053214 Free PMC article.
DUX4 expression in FSHD muscle cells: how could such a rare protein cause a myopathy?
Tassin A, Laoudj-Chenivesse D, Vanderplanck C, Barro M, Charron S, Ansseau E, Chen YW, Mercier J, Coppée F, Belayew A. Tassin A, et al. Among authors: ansseau e. J Cell Mol Med. 2013 Jan;17(1):76-89. doi: 10.1111/j.1582-4934.2012.01647.x. Epub 2012 Dec 4. J Cell Mol Med. 2013. PMID: 23206257 Free PMC article.
Defective regulation of microRNA target genes in myoblasts from facioscapulohumeral dystrophy patients.
Dmitriev P, Stankevicins L, Ansseau E, Petrov A, Barat A, Dessen P, Robert T, Turki A, Lazar V, Labourer E, Belayew A, Carnac G, Laoudj-Chenivesse D, Lipinski M, Vassetzky YS. Dmitriev P, et al. Among authors: ansseau e. J Biol Chem. 2013 Dec 6;288(49):34989-5002. doi: 10.1074/jbc.M113.504522. Epub 2013 Oct 20. J Biol Chem. 2013. PMID: 24145033 Free PMC article.
Homologous Transcription Factors DUX4 and DUX4c Associate with Cytoplasmic Proteins during Muscle Differentiation.
Ansseau E, Eidahl JO, Lancelot C, Tassin A, Matteotti C, Yip C, Liu J, Leroy B, Hubeau C, Gerbaux C, Cloet S, Wauters A, Zorbo S, Meyer P, Pirson I, Laoudj-Chenivesse D, Wattiez R, Harper SQ, Belayew A, Coppée F. Ansseau E, et al. PLoS One. 2016 Jan 27;11(1):e0146893. doi: 10.1371/journal.pone.0146893. eCollection 2016. PLoS One. 2016. PMID: 26816005 Free PMC article.
18 results