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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1965 1
1970 1
1975 1
1976 1
1977 4
1978 1
1979 1
1980 1
1981 2
1982 1
1983 2
1984 6
1985 2
1986 1
1987 3
1988 4
1989 7
1990 5
1991 6
1992 3
1993 6
1994 3
1995 2
1996 3
1997 9
1998 4
1999 5
2000 5
2001 4
2002 7
2003 15
2004 10
2005 8
2006 17
2007 19
2008 14
2009 19
2010 11
2011 29
2012 41
2013 35
2014 44
2015 50
2016 48
2017 52
2018 39
2019 47
2020 41
2021 39
2022 53
2023 63
2024 52
2025 74
2026 26

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880 results

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The following term was not found in PubMed: straanded
Page 1
Archival single-cell genomics reveals persistent subclones during DCIS progression.
Wang K, Kumar T, Wang J, Minussi DC, Sei E, Li J, Tran TM, Thennavan A, Hu M, Casasent AK, Xiao Z, Bai S, Yang L, King LM, Shah V, Kristel P, van der Borden CL, Marks JR, Zhao Y, Zurita AJ, Aparicio A, Chapin B, Ye J, Zhang J, Gibbons DL; Grand Challenge PRECISION Consortium; Sawyer E, Thompson AM, Futreal A, Hwang ES, Wesseling J, Lips EH, Navin NE. Wang K, et al. Cell. 2023 Aug 31;186(18):3968-3982.e15. doi: 10.1016/j.cell.2023.07.024. Epub 2023 Aug 15. Cell. 2023. PMID: 37586362 Free PMC article.
Here, we developed Arc-well, a high-throughput single-cell DNA-sequencing method that is compatible with FFPE materials. We validated our method by profiling 40,330 single cells from cell lines, a frozen tissue, and 27 FFPE samples from breast, lung, and pros …
Here, we developed Arc-well, a high-throughput single-cell DNA-sequencing method that is compatible with FFPE materials. We va …
Diabetic autonomic neuropathy.
Vinik AI, Maser RE, Mitchell BD, Freeman R. Vinik AI, et al. Diabetes Care. 2003 May;26(5):1553-79. doi: 10.2337/diacare.26.5.1553. Diabetes Care. 2003. PMID: 12716821 Review.
Diabetic autonomic neuropathy (DAN) is a serious and common complication of diabetes. Despite its relationship to an increased risk of cardiovascular mortality and its association with multiple symptoms and impairments, the significance of DAN has not been fully app …
Diabetic autonomic neuropathy (DAN) is a serious and common complication of diabetes. Despite its relationship to an increased risk o …
Targeting LYPLAL1-mediated cGAS depalmitoylation enhances the response to anti-tumor immunotherapy.
Fan Y, Gao Y, Nie L, Hou T, Dan W, Wang Z, Liu T, Wei Y, Wang Y, Liu B, Que T, Lei Y, Zeng J, Ma J, Wei W, Li L. Fan Y, et al. Mol Cell. 2023 Oct 5;83(19):3520-3532.e7. doi: 10.1016/j.molcel.2023.09.007. Mol Cell. 2023. PMID: 37802025 Free article.
Cyclic GMP-AMP synthase (cGAS) binds pathogenic and other cytoplasmic double-stranded DNA (dsDNA) to catalyze the synthesis of cyclic GMP-AMP (cGAMP), which serves as the secondary messenger to activate the STING pathway and innate immune responses. .. …
Cyclic GMP-AMP synthase (cGAS) binds pathogenic and other cytoplasmic double-stranded DNA (dsDNA) to catalyze th …
AI-MARRVEL - A Knowledge-Driven AI System for Diagnosing Mendelian Disorders.
Mao D, Liu C, Wang L, Ai-Ouran R, Deisseroth C, Pasupuleti S, Kim SY, Li L, Rosenfeld JA, Meng L, Burrage LC, Wangler MF, Yamamoto S; Undiagnosed Diseases Network; Santana M, Perez V, Shukla P, Eng CM, Lee B, Yuan B, Xia F, Bellen HJ, Liu P, Liu Z. Mao D, et al. NEJM AI. 2024 May;1(5):10.1056/aioa2300009. doi: 10.1056/aioa2300009. Epub 2024 Apr 25. NEJM AI. 2024. PMID: 38962029 Free PMC article.
RESULTS: AIM improved the rate of accurate genetic diagnosis, doubling the number of solved cases as compared with benchmarked methods, across three distinct real-world cohorts. ...
RESULTS: AIM improved the rate of accurate genetic diagnosis, doubling the number of solved cases as compared with benchmarked method …
A randomized, double-blind, placebo-controlled study of daily cannabidiol for the treatment of canine osteoarthritis pain.
Verrico CD, Wesson S, Konduri V, Hofferek CJ, Vazquez-Perez J, Blair E, Dunner K Jr, Salimpour P, Decker WK, Halpert MM. Verrico CD, et al. Pain. 2020 Sep 1;161(9):2191-2202. doi: 10.1097/j.pain.0000000000001896. Pain. 2020. PMID: 32345916 Free PMC article.
Subsequently, the therapeutic potential of both naked and liposomally encapsulated CBD was explored in a 4-week, randomized placebo-controlled, double-blinded study in a spontaneous canine model of OA. In vitro and in mouse models, CBD significantly attenuated the producti …
Subsequently, the therapeutic potential of both naked and liposomally encapsulated CBD was explored in a 4-week, randomized placebo-controll …
Parallel stranded DNA.
van de Sande JH, Ramsing NB, Germann MW, Elhorst W, Kalisch BW, von Kitzing E, Pon RT, Clegg RC, Jovin TM. van de Sande JH, et al. Science. 1988 Jul 29;241(4865):551-7. doi: 10.1126/science.3399890. Science. 1988. PMID: 3399890
(iv) The ultraviolet absorption and circular dichroism spectra are indicative of a base-paired duplex in the stems of the ps hairpins but differ systematically from those of the aps counterparts. (v) The bis-benzimidazole drug Hoechst-33258, which binds in the minor …
(iv) The ultraviolet absorption and circular dichroism spectra are indicative of a base-paired duplex in the stems of the ps hairpins but …
Anti-DNA antibodies exhibit different binding motif preferences for single stranded or double stranded DNA.
Wang Y, Mi J, Cao X. Wang Y, et al. Immunol Lett. 2000 Jul 3;73(1):29-34. doi: 10.1016/s0165-2478(00)00194-2. Immunol Lett. 2000. PMID: 10963808
A common feature for most anti-DNA antibodies (Abs) is their induction in an antigen (Ag)-driven specific clonal expansion pattern though crossreactivity. ...We show that the fragments of ss- or ds- form bound by a same stock of antibodies were diff …
A common feature for most anti-DNA antibodies (Abs) is their induction in an antigen (Ag)-driven specific clonal expans …
Epilepsy in autism.
Tuchman R, Rapin I. Tuchman R, et al. Lancet Neurol. 2002 Oct;1(6):352-8. doi: 10.1016/s1474-4422(02)00160-6. Lancet Neurol. 2002. PMID: 12849396 Review.
There is no evidence-based treatment recommendation for individuals with autism, regression, and subclinical epilepsy. Double-blind studies with sufficient power to resolve this issue are urgently needed....
There is no evidence-based treatment recommendation for individuals with autism, regression, and subclinical epilepsy. Double-blind s …
Dihydrotanshinone I targets ESR1 to induce DNA double-strand breaks and proliferation inhibition in hepatocellular carcinoma.
Nie Y, Yan J, Huang X, Jiang T, Zhang S, Zhang G. Nie Y, et al. Phytomedicine. 2024 Jul 25;130:155767. doi: 10.1016/j.phymed.2024.155767. Epub 2024 May 24. Phytomedicine. 2024. PMID: 38833789
Multiple in vitro and in vivo experiments were used to identify whether i) ESR1 is a crucial gene that promotes DNA double-strand breaks (DSBs) and proliferation inhibition in HCC, ii) Dihydrotanshinone I (DHT), a quinonoid monomeric constituent derived from …
Multiple in vitro and in vivo experiments were used to identify whether i) ESR1 is a crucial gene that promotes DNA double- …
Discovery of novel DNA-damaging agents through phenotypic screening for DNA double-strand break.
Zhang D, Shimokawa T, Guo Q, Dan S, Miki Y, Sunada S. Zhang D, et al. Cancer Sci. 2023 Mar;114(3):1108-1117. doi: 10.1111/cas.15659. Epub 2022 Nov 30. Cancer Sci. 2023. PMID: 36385507 Free PMC article.
DNA double-strand breaks (DSBs) seriously damage DNA and promote genomic instability that can lead to cell death. ...We screened a chemical library containing 9600 compounds and detected multiple DNA-damaging compounds, although we could not ide …
DNA double-strand breaks (DSBs) seriously damage DNA and promote genomic instability that can lead to cell death …
880 results