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Anti-MMP-9 Antibody: A Promising Therapeutic Strategy for Treatment of Inflammatory Bowel Disease Complications with Fibrosis.
Goffin L, Fagagnini S, Vicari A, Mamie C, Melhem H, Weder B, Lutz C, Lang S, Scharl M, Rogler G, Chvatchko Y, Hausmann M. Goffin L, et al. Inflamm Bowel Dis. 2016 Sep;22(9):2041-57. doi: 10.1097/MIB.0000000000000863. Inflamm Bowel Dis. 2016. PMID: 27542125
Therapeutic efficacy of anti-MMP-9 monoclonal antibodies was assessed in a heterotopic xenograft model of intestinal fibrosis. ...Anti-MMP-9 treatments reduced collagen deposition and hydroxyproline content in
Therapeutic efficacy of anti-MMP-9 monoclonal antibodies was assessed in a heterotopic xenograft model of