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Akt is upstream and MAPKs are downstream of NF-κB in paclitaxel-induced survival signaling events, which are down-regulated by curcumin contributing to their synergism.
Bava SV, Sreekanth CN, Thulasidasan AK, Anto NP, Cheriyan VT, Puliyappadamba VT, Menon SG, Ravichandran SD, Anto RJ. Bava SV, et al. Among authors: anto rj, anto np. Int J Biochem Cell Biol. 2011 Mar;43(3):331-41. doi: 10.1016/j.biocel.2010.09.011. Epub 2010 Sep 29. Int J Biochem Cell Biol. 2011. PMID: 20883815
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