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Prostaglandin E2 stimulates p53 transactivational activity through specific serine 15 phosphorylation in human synovial fibroblasts. Role in suppression of c/EBP/NF-kappaB-mediated MEKK1-induced MMP-1 expression.
Faour WH, He Q, Mancini A, Jovanovic D, Antoniou J, Di Battista JA. Faour WH, et al. Among authors: antoniou j. J Biol Chem. 2006 Jul 21;281(29):19849-60. doi: 10.1074/jbc.M601293200. Epub 2006 May 19. J Biol Chem. 2006. PMID: 16714289 Free article.
Prostaglandin PGE2 at very low concentrations suppresses collagen cleavage in cultured human osteoarthritic articular cartilage: this involves a decrease in expression of proinflammatory genes, collagenases and COL10A1, a gene linked to chondrocyte hypertrophy.
Tchetina EV, Di Battista JA, Zukor DJ, Antoniou J, Poole AR. Tchetina EV, et al. Among authors: antoniou j. Arthritis Res Ther. 2007;9(4):R75. doi: 10.1186/ar2273. Arthritis Res Ther. 2007. PMID: 17683641 Free PMC article.
Endoglin differentially regulates TGF-β-induced Smad2/3 and Smad1/5 signalling and its expression correlates with extracellular matrix production and cellular differentiation state in human chondrocytes.
Finnson KW, Parker WL, Chi Y, Hoemann CD, Goldring MB, Antoniou J, Philip A. Finnson KW, et al. Among authors: antoniou j. Osteoarthritis Cartilage. 2010 Nov;18(11):1518-27. doi: 10.1016/j.joca.2010.09.002. Epub 2010 Sep 15. Osteoarthritis Cartilage. 2010. PMID: 20833252 Free article.
219 results