Antoniw P - Search Results

1

Prolonged in vivo residence times of antibody fragments associated with albumin.

Smith BJ, Popplewell A, Athwal D, Chapman AP, Heywood S, West SM, Carrington B, Nesbitt A, Lawson AD, Antoniw P, Eddelston A, Suitters A. Smith BJ, et al. Among authors: antoniw p. Bioconjug Chem. 2001 Sep-Oct;12(5):750-6. doi: 10.1021/bc010003g. Bioconjug Chem. 2001. PMID: 11562193

2

Therapeutic antibody fragments with prolonged in vivo half-lives.

Chapman AP, Antoniw P, Spitali M, West S, Stephens S, King DJ. Chapman AP, et al. Among authors: antoniw p. Nat Biotechnol. 1999 Aug;17(8):780-3. doi: 10.1038/11717. Nat Biotechnol. 1999. PMID: 10429243

3

Formatting antibody fragments to mediate specific therapeutic functions.

Weir AN, Nesbitt A, Chapman AP, Popplewell AG, Antoniw P, Lawson AD. Weir AN, et al. Among authors: antoniw p. Biochem Soc Trans. 2002 Aug;30(4):512-6. doi: 10.1042/bst0300512. Biochem Soc Trans. 2002. PMID: 12196125 Review.

4

F(ab')2 molecules made from Escherichia coli produced Fab' with hinge sequences conferring increased serum survival in an animal model.

Humphreys DP, Vetterlein OM, Chapman AP, King DJ, Antoniw P, Suitters AJ, Reeks DG, Parton TA, King LM, Smith BJ, Lang V, Stephens PE. Humphreys DP, et al. Among authors: antoniw p. J Immunol Methods. 1998 Aug 1;217(1-2):1-10. doi: 10.1016/s0022-1759(98)00061-1. J Immunol Methods. 1998. PMID: 9776570

5

Alternative antibody Fab' fragment PEGylation strategies: combination of strong reducing agents, disruption of the interchain disulphide bond and disulphide engineering.

Humphreys DP, Heywood SP, Henry A, Ait-Lhadj L, Antoniw P, Palframan R, Greenslade KJ, Carrington B, Reeks DG, Bowering LC, West S, Brand HA. Humphreys DP, et al. Among authors: antoniw p. Protein Eng Des Sel. 2007 May;20(5):227-34. doi: 10.1093/protein/gzm015. Epub 2007 Apr 23. Protein Eng Des Sel. 2007. PMID: 17452434

6

Preparation and preclinical evaluation of humanised A33 immunoconjugates for radioimmunotherapy.

King DJ, Antoniw P, Owens RJ, Adair JR, Haines AM, Farnsworth AP, Finney H, Lawson AD, Lyons A, Baker TS, et al. King DJ, et al. Among authors: antoniw p. Br J Cancer. 1995 Dec;72(6):1364-72. doi: 10.1038/bjc.1995.516. Br J Cancer. 1995. PMID: 8519646 Free PMC article.

7

Radioimmunotherapy of colorectal carcinoma xenografts in nude mice with yttrium-90 A33 IgG and Tri-Fab (TFM).

Antoniw P, Farnsworth AP, Turner A, Haines AM, Mountain A, Mackintosh J, Shochat D, Humm J, Welt S, Old LJ, Yarranton GT, King DJ. Antoniw P, et al. Br J Cancer. 1996 Aug;74(4):513-24. doi: 10.1038/bjc.1996.395. Br J Cancer. 1996. PMID: 8761364 Free PMC article.

8

An in vivo model for screening peptidomimetic inhibitors of gelatinase A.

Chander SK, Antoniw P, Beeley NR, Boyce B, Crabbe T, Docherty AJ, Leonard J, Mason B, Millar K, Millican AT, et al. Chander SK, et al. Among authors: antoniw p. J Pharm Sci. 1995 Apr;84(4):404-9. doi: 10.1002/jps.2600840405. J Pharm Sci. 1995. PMID: 7629728

9

Disposition of the prodrug 4-(bis (2-chloroethyl) amino) benzoyl-L-glutamic acid and its active parent drug in mice.

Antoniw P, Springer CJ, Bagshawe KD, Searle F, Melton RG, Rogers GT, Burke PJ, Sherwood RF. Antoniw P, et al. Br J Cancer. 1990 Dec;62(6):909-14. doi: 10.1038/bjc.1990.407. Br J Cancer. 1990. PMID: 2257218 Free PMC article.

10

A cytotoxic agent can be generated selectively at cancer sites.

Bagshawe KD, Springer CJ, Searle F, Antoniw P, Sharma SK, Melton RG, Sherwood RF. Bagshawe KD, et al. Among authors: antoniw p. Br J Cancer. 1988 Dec;58(6):700-3. doi: 10.1038/bjc.1988.293. Br J Cancer. 1988. PMID: 3265633 Free PMC article.

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