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Bone marrow cells regenerate infarcted myocardium.
Orlic D, Kajstura J, Chimenti S, Jakoniuk I, Anderson SM, Li B, Pickel J, McKay R, Nadal-Ginard B, Bodine DM, Leri A, Anversa P. Orlic D, et al. Among authors: anversa p. Nature. 2001 Apr 5;410(6829):701-5. doi: 10.1038/35070587. Nature. 2001. PMID: 11287958
Morphometric analysis of the infarcted heart.
Anversa P, Capasso JM, Puntillo E, Sonnenblick EH, Olivetti G. Anversa P, et al. Pathol Res Pract. 1989 Nov;185(5):544-50. doi: 10.1016/S0344-0338(89)80190-6. Pathol Res Pract. 1989. PMID: 2533977
Mobilized bone marrow cells repair the infarcted heart, improving function and survival.
Orlic D, Kajstura J, Chimenti S, Limana F, Jakoniuk I, Quaini F, Nadal-Ginard B, Bodine DM, Leri A, Anversa P. Orlic D, et al. Among authors: anversa p. Proc Natl Acad Sci U S A. 2001 Aug 28;98(18):10344-9. doi: 10.1073/pnas.181177898. Epub 2001 Aug 14. Proc Natl Acad Sci U S A. 2001. PMID: 11504914 Free PMC article.
Regeneration of the infarcted heart with stem cells derived by nuclear transplantation.
Lanza R, Moore MA, Wakayama T, Perry AC, Shieh JH, Hendrikx J, Leri A, Chimenti S, Monsen A, Nurzynska D, West MD, Kajstura J, Anversa P. Lanza R, et al. Among authors: anversa p. Circ Res. 2004 Apr 2;94(6):820-7. doi: 10.1161/01.RES.0000120863.53562.DF. Epub 2004 Feb 5. Circ Res. 2004. PMID: 14764454
Bone marrow stem cells regenerate infarcted myocardium.
Orlic D, Kajstura J, Chimenti S, Bodine DM, Leri A, Anversa P. Orlic D, et al. Among authors: anversa p. Pediatr Transplant. 2003;7 Suppl 3:86-8. doi: 10.1034/j.1399-3046.7.s3.13.x. Pediatr Transplant. 2003. PMID: 12603699 Review.
Stem cells: bone-marrow-derived cells and heart failure--the debate goes on.
Leri A, Anversa P. Leri A, et al. Among authors: anversa p. Nat Rev Cardiol. 2013 Jul;10(7):372-3. doi: 10.1038/nrcardio.2013.81. Epub 2013 May 28. Nat Rev Cardiol. 2013. PMID: 23712104 Free PMC article.
Bone marrow cells adopt the cardiomyogenic fate in vivo.
Rota M, Kajstura J, Hosoda T, Bearzi C, Vitale S, Esposito G, Iaffaldano G, Padin-Iruegas ME, Gonzalez A, Rizzi R, Small N, Muraski J, Alvarez R, Chen X, Urbanek K, Bolli R, Houser SR, Leri A, Sussman MA, Anversa P. Rota M, et al. Among authors: anversa p. Proc Natl Acad Sci U S A. 2007 Nov 6;104(45):17783-8. doi: 10.1073/pnas.0706406104. Epub 2007 Oct 26. Proc Natl Acad Sci U S A. 2007. PMID: 17965233 Free PMC article.
Cardiac stem cells delivered intravascularly traverse the vessel barrier, regenerate infarcted myocardium, and improve cardiac function.
Dawn B, Stein AB, Urbanek K, Rota M, Whang B, Rastaldo R, Torella D, Tang XL, Rezazadeh A, Kajstura J, Leri A, Hunt G, Varma J, Prabhu SD, Anversa P, Bolli R. Dawn B, et al. Among authors: anversa p. Proc Natl Acad Sci U S A. 2005 Mar 8;102(10):3766-71. doi: 10.1073/pnas.0405957102. Epub 2005 Feb 25. Proc Natl Acad Sci U S A. 2005. PMID: 15734798 Free PMC article.
Cardiac stem cells possess growth factor-receptor systems that after activation regenerate the infarcted myocardium, improving ventricular function and long-term survival.
Urbanek K, Rota M, Cascapera S, Bearzi C, Nascimbene A, De Angelis A, Hosoda T, Chimenti S, Baker M, Limana F, Nurzynska D, Torella D, Rotatori F, Rastaldo R, Musso E, Quaini F, Leri A, Kajstura J, Anversa P. Urbanek K, et al. Among authors: anversa p. Circ Res. 2005 Sep 30;97(7):663-73. doi: 10.1161/01.RES.0000183733.53101.11. Epub 2005 Sep 1. Circ Res. 2005. PMID: 16141414
Stem cells in the dog heart are self-renewing, clonogenic, and multipotent and regenerate infarcted myocardium, improving cardiac function.
Linke A, Müller P, Nurzynska D, Casarsa C, Torella D, Nascimbene A, Castaldo C, Cascapera S, Böhm M, Quaini F, Urbanek K, Leri A, Hintze TH, Kajstura J, Anversa P. Linke A, et al. Among authors: anversa p. Proc Natl Acad Sci U S A. 2005 Jun 21;102(25):8966-71. doi: 10.1073/pnas.0502678102. Epub 2005 Jun 10. Proc Natl Acad Sci U S A. 2005. PMID: 15951423 Free PMC article.
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