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1999 1
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2014 7
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116 results

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Knockdown of ANXA10 induces ferroptosis by inhibiting autophagy-mediated TFRC degradation in colorectal cancer.
Wang X, Zhou Y, Ning L, Chen J, Chen H, Li X. Wang X, et al. Cell Death Dis. 2023 Sep 4;14(9):588. doi: 10.1038/s41419-023-06114-2. Cell Death Dis. 2023. PMID: 37666806 Free PMC article.
The effect of ANXA10 on lung metastasis of xenograft tumor cells in nude mice was also assessed. ...ANXA10 knockdown reduced the survival, proliferation, and migration ability of CRC cells. ...
The effect of ANXA10 on lung metastasis of xenograft tumor cells in nude mice was also assessed. ...ANXA10 knockdown reduced t …
ANXA10 promotes melanoma metastasis by suppressing E3 ligase TRIM41-directed PKD1 degradation.
Zhang X, Hu Z, Wang X, Li L, Zhu B, Lin X, Zhang J, Hua Z. Zhang X, et al. Cancer Lett. 2021 Oct 28;519:237-249. doi: 10.1016/j.canlet.2021.07.033. Epub 2021 Jul 26. Cancer Lett. 2021. PMID: 34324862 Free article.
ANXA10 knockout profoundly reduces cell migration and the metastatic activity of melanoma. ...The negative regulation of SMAD6 by ANXA10 is dependent on PKD1. ANXA10 interacts with PKD1 and inhibits E3 ligase TRIM41-targeted PKD1 degradation. ...
ANXA10 knockout profoundly reduces cell migration and the metastatic activity of melanoma. ...The negative regulation of SMAD6 by …
ANXA10 is a prognostic biomarker and suppressor of hepatocellular carcinoma: a bioinformatics analysis and experimental validation.
Zhang C, Peng L, Gu H, Wang J, Wang Y, Xu Z. Zhang C, et al. Sci Rep. 2023 Jan 28;13(1):1583. doi: 10.1038/s41598-023-28527-x. Sci Rep. 2023. PMID: 36709331 Free PMC article.
Liver hepatocellular carcinoma (LIHC) is one of the main cancers worldwide and has high morbidity and mortality rates. Although previous studies have shown that ANXA10 is expressed at low levels in LIHC tumor tissues, the biological function of ANXA10 in LIHC is sti …
Liver hepatocellular carcinoma (LIHC) is one of the main cancers worldwide and has high morbidity and mortality rates. Although previous stu …
ANXA10 Expression Is Inversely Associated with Tumor Stage, Grade, and TP53 Expression in Upper and Lower Urothelial Carcinoma.
Kobayashi G, Hayashi T, Sentani K, Ikeda K, Babasaki T, Shigematsu Y, Sekino Y, Uraoka N, Teishima J, Matsubara A, Hinata N, Oue N. Kobayashi G, et al. Pathobiology. 2023;90(2):94-103. doi: 10.1159/000524989. Epub 2022 Jul 1. Pathobiology. 2023. PMID: 35780773
The association between ANXA10 expression and representative cancer-related molecules was also evaluated. ...ANXA10-positive patients showed better cancer-specific survival and progression-free survival than ANXA10-negative patients (p < 0.05). ...
The association between ANXA10 expression and representative cancer-related molecules was also evaluated. ...ANXA10-positive p …
Mouse Models of Human Gastric Cancer Subtypes With Stomach-Specific CreERT2-Mediated Pathway Alterations.
Seidlitz T, Chen YT, Uhlemann H, Schölch S, Kochall S, Merker SR, Klimova A, Hennig A, Schweitzer C, Pape K, Baretton GB, Welsch T, Aust DE, Weitz J, Koo BK, Stange DE. Seidlitz T, et al. Gastroenterology. 2019 Dec;157(6):1599-1614.e2. doi: 10.1053/j.gastro.2019.09.026. Epub 2019 Oct 1. Gastroenterology. 2019. PMID: 31585123 Free PMC article.
METHODS: We searched databases to identify genes with unique expression in the stomach epithelium, resulting in the identification of Anxa10. We generated mice with tamoxifen-inducible Cre recombinase (CreERT2) in the Anxa10 gene locus. We created 3 mouse models wit …
METHODS: We searched databases to identify genes with unique expression in the stomach epithelium, resulting in the identification of Anx …
Knockdown of ANXA10 inhibits proliferation and promotes apoptosis of papillary thyroid carcinoma cells by down-regulating TSG101 thereby inactivating the MAPK/ERK signaling pathway.
Wei T, Zhu X. Wei T, et al. J Bioenerg Biomembr. 2021 Aug;53(4):429-440. doi: 10.1007/s10863-021-09902-7. Epub 2021 May 25. J Bioenerg Biomembr. 2021. PMID: 34032966
Tumor susceptibility gene 101 (TSG101) also plays a role in PTC and is predicted to bind to ANXA10. This study intended to investigate whether ANXA10 could regulate PTC via binding to ANXA10. ...ANXA10 and TSG101 expressions were up-regulated in PTC ce …
Tumor susceptibility gene 101 (TSG101) also plays a role in PTC and is predicted to bind to ANXA10. This study intended to investigat …
Low ANXA10 expression is associated with disease aggressiveness in bladder cancer.
Munksgaard PP, Mansilla F, Brems Eskildsen AS, Fristrup N, Birkenkamp-Demtröder K, Ulhøi BP, Borre M, Agerbæk M, Hermann GG, Orntoft TF, Dyrskjøt L. Munksgaard PP, et al. Br J Cancer. 2011 Oct 25;105(9):1379-87. doi: 10.1038/bjc.2011.404. Epub 2011 Oct 6. Br J Cancer. 2011. PMID: 21979422 Free PMC article.
The expression of ANXA10 was also investigated in an additional set of 97 more advanced tumours. The functional role of ANXA10 in cell lines was investigated by siRNA-mediated ANXA10 knockdown using wound-healing assays, proliferation assays, and ingenuity pa …
The expression of ANXA10 was also investigated in an additional set of 97 more advanced tumours. The functional role of ANXA10 …
ANXA10 induction by interaction with tumor-associated macrophages promotes the growth of esophageal squamous cell carcinoma.
Kodaira H, Koma YI, Hosono M, Higashino N, Suemune K, Nishio M, Shigeoka M, Yokozaki H. Kodaira H, et al. Pathol Int. 2019 Mar;69(3):135-147. doi: 10.1111/pin.12771. Epub 2019 Feb 13. Pathol Int. 2019. PMID: 30758105 Free PMC article.
Our qRT-PCR confirmed that in the co-cultured ESCC cell lines, CYP1A1, DHRS3, ANXA10, KLK6 and CYP1B1 mRNA were highly up-regulated; AMTN and IGFL1 mRNA were down-regulated. ...We also found ANXA10 promoted the cell growth of ESCC cell lines via the phosphorylation …
Our qRT-PCR confirmed that in the co-cultured ESCC cell lines, CYP1A1, DHRS3, ANXA10, KLK6 and CYP1B1 mRNA were highly up-regulated; …
Single-Cell Transcriptome Profiling of Pancreatic Islets From Early Diabetic Mice Identifies Anxa10 for Ca2+ Allostasis Toward beta-Cell Failure.
Motomura K, Matsuzaka T, Shichino S, Ogawa T, Pan H, Nakajima T, Asano Y, Okayama T, Takeuchi T, Ohno H, Han SI, Miyamoto T, Takeuchi Y, Sekiya M, Sone H, Yahagi N, Nakagawa Y, Oda T, Ueha S, Ikeo K, Ogura A, Matsushima K, Shimano H. Motomura K, et al. Diabetes. 2024 Jan 1;73(1):75-92. doi: 10.2337/db23-0212. Diabetes. 2024. PMID: 37871012 Free PMC article.
We discovered a diabetes-specific transcriptome landscape of endocrine and nonendocrine cell types with subpopulations of beta- and alpha-cells. We recognized a new prediabetic gene, Anxa10, that was induced by and regulated Ca2+ influx from metabolic stresses. Anxa10 …
We discovered a diabetes-specific transcriptome landscape of endocrine and nonendocrine cell types with subpopulations of beta- and alpha-ce …
116 results