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Ventilator settings as a risk factor for acute respiratory distress syndrome in mechanically ventilated patients.
Gajic O, Frutos-Vivar F, Esteban A, Hubmayr RD, Anzueto A. Gajic O, et al. Intensive Care Med. 2005 Jul;31(7):922-6. doi: 10.1007/s00134-005-2625-1. Epub 2005 Apr 26. Intensive Care Med. 2005. PMID: 15856172
We tested this hypothesis in a larger sample of patients prospectively enrolled in a multicenter study on mechanical ventilation. ...This hypothesis needs to be tested in a prospective study....
We tested this hypothesis in a larger sample of patients prospectively enrolled in a multicenter study on mechanical ventilati …
Effects of guideline-concordant antimicrobial therapy on mortality among patients with community-acquired pneumonia.
Mortensen EM, Restrepo M, Anzueto A, Pugh J. Mortensen EM, et al. Am J Med. 2004 Nov 15;117(10):726-31. doi: 10.1016/j.amjmed.2004.06.028. Am J Med. 2004. PMID: 15541321
METHODS: We conducted a retrospective cohort study at two tertiary teaching hospitals. Eligible patients were admitted with a diagnosis of community-acquired pneumonia, had a chest radiograph consistent with pneumonia, and had a discharge diagnosis of …
METHODS: We conducted a retrospective cohort study at two tertiary teaching hospitals. Eligible patients were admitted with a
Antibiotics for acute and chronic respiratory infection in patients with chronic obstructive pulmonary disease.
Miravitlles M, Anzueto A. Miravitlles M, et al. Am J Respir Crit Care Med. 2013 Nov 1;188(9):1052-7. doi: 10.1164/rccm.201302-0289PP. Am J Respir Crit Care Med. 2013. PMID: 23924286
These aspects have led to recommendations for a stratified approach to antibiotic therapy based on patient characteristics associated with increased risk factors for failure. ...Although systemic antibiotics are likely to remain the core treatment for patients with moderat …
These aspects have led to recommendations for a stratified approach to antibiotic therapy based on patient characteristics associated …
Association between a silver-coated endotracheal tube and reduced mortality in patients with ventilator-associated pneumonia.
Afessa B, Shorr AF, Anzueto AR, Craven DE, Schinner R, Kollef MH. Afessa B, et al. Chest. 2010 May;137(5):1015-21. doi: 10.1378/chest.09-0391. Epub 2009 Dec 28. Chest. 2010. PMID: 20038737
In multivariate analysis, the treatment group was a predictor of mortality (odds ratio, silver vs control, 0.28; 95% CI, 0.09-0.89; P = .03). ...CONCLUSIONS: These findings suggest that a silver-coated ETT was associated with reduced mortality in patients who develo …
In multivariate analysis, the treatment group was a predictor of mortality (odds ratio, silver vs control, 0.28; 95% CI, 0.09-0.89; P …
Bronchopulmonary segmental lavage with Surfaxin (KL(4)-surfactant) for acute respiratory distress syndrome.
Wiswell TE, Smith RM, Katz LB, Mastroianni L, Wong DY, Willms D, Heard S, Wilson M, Hite RD, Anzueto A, Revak SD, Cochrane CG. Wiswell TE, et al. Am J Respir Crit Care Med. 1999 Oct;160(4):1188-95. doi: 10.1164/ajrccm.160.4.9808118. Am J Respir Crit Care Med. 1999. PMID: 10508806 Clinical Trial.
Group 1 patients (n = 3) received one 30-ml aliquot of a 2.5-mg/ml concentration of Surfaxin in each segment, followed by a second 30-ml aliquot with a 10-mg/ml concentration. ...Wiswell TE, Smith RM, Katz LB, Mastroianni L, Wong DY, Willms D, Heard S, Wilson …
Group 1 patients (n = 3) received one 30-ml aliquot of a 2.5-mg/ml concentration of Surfaxin in each segment, followed by a se …
The relation of pneumothorax and other air leaks to mortality in the acute respiratory distress syndrome.
Weg JG, Anzueto A, Balk RA, Wiedemann HP, Pattishall EN, Schork MA, Wagner LA. Weg JG, et al. N Engl J Med. 1998 Feb 5;338(6):341-6. doi: 10.1056/NEJM199802053380601. N Engl J Med. 1998. PMID: 9449726 Clinical Trial.
METHODS: We analyzed data from a prospective trial of aerosolized synthetic surfactant in 725 patients with the acute respiratory distress syndrome induced by sepsis. ...Pneumothorax or other air leaks were not associated with a significantly increased mortality rat …
METHODS: We analyzed data from a prospective trial of aerosolized synthetic surfactant in 725 patients with the acute respiratory dis …
Acute respiratory distress syndrome. Liquid ventilation.
Anzueto A, Melo J. Anzueto A, et al. Respir Care Clin N Am. 1998 Dec;4(4):679-94. Respir Care Clin N Am. 1998. PMID: 9881399 Review.
[Prognosis for acute exacerbation of chronic obstructive pulmonary disease in mechanically ventilated patients].
Frutos-Vivar F, Esteban A, Anzueto A, Apezteguia C, González M, Bugedo G, D'Empaire G, Palizas F, Elizalde J, Soto L, David CM, Rodrigo C; International Study Mechanical Ventilation Group. Frutos-Vivar F, et al. Med Intensiva. 2006 Mar;30(2):52-61. doi: 10.1016/s0210-5691(06)74469-2. Med Intensiva. 2006. PMID: 16706329 Clinical Trial. Spanish.
In order to determine those variables associated with mortality, there was performed a recursive partition analysis in which the following variables were included: demographics, arterial blood gas prior to intubation, complications arising during mechanical ventilation (ba …
In order to determine those variables associated with mortality, there was performed a recursive partition analysis in which the foll …
Understanding international differences in terminology for delirium and other types of acute brain dysfunction in critically ill patients.
Morandi A, Pandharipande P, Trabucchi M, Rozzini R, Mistraletti G, Trompeo AC, Gregoretti C, Gattinoni L, Ranieri MV, Brochard L, Annane D, Putensen C, Guenther U, Fuentes P, Tobar E, Anzueto AR, Esteban A, Skrobik Y, Salluh JI, Soares M, Granja C, Stubhaug A, de Rooij SE, Ely EW. Morandi A, et al. Intensive Care Med. 2008 Oct;34(10):1907-15. doi: 10.1007/s00134-008-1177-6. Epub 2008 Jun 18. Intensive Care Med. 2008. PMID: 18563387
BACKGROUND: Delirium (acute brain dysfunction) is a potentially life threatening disturbance in brain function that frequently occurs in critically ill patients. ...
BACKGROUND: Delirium (acute brain dysfunction) is a potentially life threatening disturbance in brain function that frequently occurs …
Acute Kidney Injury in Mechanically Ventilated Patients: The Risk Factor Profile Depends on the Timing of Aki Onset.
Lombardi R, Nin N, Peñuelas O, Ferreiro A, Rios F, Marin MC, Raymondos K, Lorente JA, Koh Y, Hurtado J, Gonzalez M, Abroug F, Jibaja M, Arabi Y, Moreno R, Matamis D, Anzueto A, Esteban A; VENTILA Group. Lombardi R, et al. Shock. 2017 Oct;48(4):411-417. doi: 10.1097/SHK.0000000000000871. Shock. 2017. PMID: 28379920 Clinical Trial.
STUDY DESIGN, SETTING, AND PARTICIPANTS: Retrospective analysis of a large, multinational database of MV patients with >24 h of MV and normal renal function at admission. ...Subsequently, emergent events like sepsis and organ dysfunction appear to be predictive factors …
STUDY DESIGN, SETTING, AND PARTICIPANTS: Retrospective analysis of a large, multinational database of MV patients with >24 h of MV …
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