Aoyama N - Search Results

1

Effect of the mutation (C3435T) at exon 26 of the MDR1 gene on expression level of MDR1 messenger ribonucleic acid in duodenal enterocytes of healthy Japanese subjects.

Nakamura T, Sakaeda T, Horinouchi M, Tamura T, Aoyama N, Shirakawa T, Matsuo M, Kasuga M, Okumura K. Nakamura T, et al. Among authors: aoyama n. Clin Pharmacol Ther. 2002 Apr;71(4):297-303. doi: 10.1067/mcp.2002.122055. Clin Pharmacol Ther. 2002. PMID: 11956513

2

Real-time quantitative polymerase chain reaction for MDR1, MRP1, MRP2, and CYP3A-mRNA levels in Caco-2 cell lines, human duodenal enterocytes, normal colorectal tissues, and colorectal adenocarcinomas.

Nakamura T, Sakaeda T, Ohmoto N, Tamura T, Aoyama N, Shirakawa T, Kamigaki T, Nakamura T, Kim KI, Kim SR, Kuroda Y, Matsuo M, Kasuga M, Okumura K. Nakamura T, et al. Among authors: aoyama n. Drug Metab Dispos. 2002 Jan;30(1):4-6. doi: 10.1124/dmd.30.1.4. Drug Metab Dispos. 2002. PMID: 11744604

3

Effects of polymorphisms of MDR1, MRP1, and MRP2 genes on their mRNA expression levels in duodenal enterocytes of healthy Japanese subjects.

Moriya Y, Nakamura T, Horinouchi M, Sakaeda T, Tamura T, Aoyama N, Shirakawa T, Gotoh A, Fujimoto S, Matsuo M, Kasuga M, Okumura K. Moriya Y, et al. Among authors: aoyama n. Biol Pharm Bull. 2002 Oct;25(10):1356-9. doi: 10.1248/bpb.25.1356. Biol Pharm Bull. 2002. PMID: 12392094 Free article.

4

Significant genetic linkage of MDR1 polymorphisms at positions 3435 and 2677: functional relevance to pharmacokinetics of digoxin.

Horinouchi M, Sakaeda T, Nakamura T, Morita Y, Tamura T, Aoyama N, Kasuga M, Okumura K. Horinouchi M, et al. Among authors: aoyama n. Pharm Res. 2002 Oct;19(10):1581-5. doi: 10.1023/a:1020433422259. Pharm Res. 2002. PMID: 12425480 No abstract available.

5

MDR1 genotype-related duodenal absorption rate of digoxin in healthy Japanese subjects.

Morita Y, Sakaeda T, Horinouchi M, Nakamura T, Kuroda K, Miki I, Yoshimura K, Sakai T, Shirasaka D, Tamura T, Aoyama N, Kasuga M, Okumura K. Morita Y, et al. Among authors: aoyama n. Pharm Res. 2003 Apr;20(4):552-6. doi: 10.1023/a:1023282312757. Pharm Res. 2003. PMID: 12739761

6

Chemosensitivity assessed by collagen gel droplet embedded culture drug sensitivity test, and MDR1, MRP1, and MRP2 mRNA expression in human colorectal adenocarcinomas.

Nakahara T, Sakaeda T, Nakamura T, Tamura T, Nishioka C, Aoyama N, Okamura N, Shirakawa T, Gotoh A, Kamigaki T, Ohno M, Kuroda Y, Matsuo M, Kasuga M, Okumura K. Nakahara T, et al. Among authors: aoyama n. Pharm Res. 2004 Mar;21(3):406-12. doi: 10.1023/B:PHAM.0000019292.03875.3e. Pharm Res. 2004. PMID: 15070089

7

MDR1, MRP1 and MRP2 genotypes and in vitro chemosensitivity in Japanese patients with colorectal adenocarcinomas.

Nishioka C, Sakaeda T, Nakamura T, Moriya Y, Okamura N, Tamura T, Nakahara T, Aoyama N, Kamigaki T, Ohno M, Kuroda Y, Kasuga M, Okumura K. Nishioka C, et al. Among authors: aoyama n. Kobe J Med Sci. 2004;50(5-6):181-8. Kobe J Med Sci. 2004. PMID: 16107775 Free article.

8

MDR1 C3435T polymorphism is predictive of later onset of ulcerative colitis in Japanese.

Osuga T, Sakaeda T, Nakamura T, Yamada T, Koyama T, Tamura T, Aoyama N, Okamura N, Kasuga M, Okumura K. Osuga T, et al. Among authors: aoyama n. Biol Pharm Bull. 2006 Feb;29(2):324-9. doi: 10.1248/bpb.29.324. Biol Pharm Bull. 2006. PMID: 16462040 Free article.

9

MDR1 T-129C polymorphism can be predictive of differentiation, and thereby prognosis of colorectal adenocarcinomas in Japanese.

Koyama T, Nakamura T, Komoto C, Sakaeda T, Taniguchi M, Okamura N, Tamura T, Aoyama N, Kamigaki T, Kuroda Y, Kasuga M, Kadoyama K, Okumura K. Koyama T, et al. Among authors: aoyama n. Biol Pharm Bull. 2006 Jul;29(7):1449-53. doi: 10.1248/bpb.29.1449. Biol Pharm Bull. 2006. PMID: 16819187 Free article.

10

MDR1 genotype-related pharmacokinetics of digoxin after single oral administration in healthy Japanese subjects.

Sakaeda T, Nakamura T, Horinouchi M, Kakumoto M, Ohmoto N, Sakai T, Morita Y, Tamura T, Aoyama N, Hirai M, Kasuga M, Okumura K. Sakaeda T, et al. Among authors: aoyama n. Pharm Res. 2001 Oct;18(10):1400-4. doi: 10.1023/a:1012244520615. Pharm Res. 2001. PMID: 11697464

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